The Architecture of Neural Repair with Dr. Pengzhe Lu

​​For decades, the diagnosis of a complete spinal cord injury came with a period at the end of the sentence: no regeneration possible. But Dr. Pengzhe Lu has spent his career challenging that finality. In this episode, we travel into the microscopic world of the Center for Neural Repair at UCSD, where Dr. Lu is engineering neural stem cell grafts to act as biological bridges across the lesion site. We explore the incredible complexity of convincing axons to grow through a hostile environment and the emerging role of 3D scaffolds in rebuilding the body’s architecture. This is a conversation about the persistence of science, the definition of the miracle year when viewed through a cellular lens, and the tangible steps being taken to translate laboratory breakthroughs into restored function for SCI families, including complete injuries, waiting for a cure.

#BeginAgain #HopeforEverything

Be part of supporting BLINK of an Eye nonprofit as we support SCI families in crisis and advance science. Give $25 today! www.BLINKofaneye.org

Resources

https://neurosciences.ucsd.edu/centers-programs/neural-repair/scientists-team/paul-lu.html

Stay Connected: Subscribe, leave a review, and share this episode with anyone interested in advocacy for SCI funding!

BLINK of an Eye® Podcast is sponsored by BLINK of an Eye® Non-Profit:

A non-profit which is an essential national resource for Spinal Cord Injury, originating the first SCI Navigator Program in the country for newly injured SCI Families by SCI Families as an essential national resource for Spinal Cord Injured families in the first days, weeks and months of SCI crisis when life turns upside down and few medical teams in the US have SCI expertise or lived experience. They bring essential support, connections, life expertise and resources. BLINK of an Eye non profit deploys a rapid response HEAL Team for ICU bedside support to create an Extraordinary Experience despite the devastation for SCI families and a personal SCI Navigator for 24/7 support in the first 90 days and throughout the Miracle Year. BLINK of an Eye non profit also provides a Multidisciplinary Wrap Around Team and SCI Expert Medical Panel. Stay tuned for their launch of a National Digital Resource Library, the SCI PLAYBOOK, chocked full of essential SCI information and trauma informed responses for the first hours, days and months after injury. To find out more, get involved, or make a donation, visit www.BLINKofaneye.org.

Blink of an Eye is sponsored by Baltimore Mediation:

To find out more about cutting edge conflict transformation skills courses to learn relational conflict theory and advocacy, mediation interventions and support for leaders and anyone navigating or facilitating difficult situations, conflict, or trauma, visit the website www.BaltimoreMediation.com and register for nationally certified 40 hour courses, including the Enneagram of personality for mediators to know themselves to stay neutral while offering opportunity for other’s empowerment.

To find out more about Louise visit: www.BlinkofanEye.org, www.BaltimoreMediation.com, www.BeingRelational.com

A Raw Look at Redefining Possibility

How do you rewrite your life's story when the plot twists become unbearable? Louise joins author Rebecca Faye Smith Galli to navigate the intersection of profound grief and the sudden onset of Transverse Myelitis. Unlike acute traumatic injury, this rare inflammatory condition presents a unique medical puzzle, attacking the spinal cord from within. Becky shares how she processed the paralysis that followed, a diagnosis that arrived amidst the heartbreaking loss of her brother and son. They explore the biology of resilience, the difference between surviving and healing, and how writing became a tool to document the intrigue of a body and life transformed. This conversation challenges the pressure to be positive, offering instead a raw look at redefining possibility when the unexpected happens.

#BeginAgain #HopeforEverything

Be part of supporting BLINK of an Eye nonprofit as we support SCI families in crisis and advance science. Give $25 today! www.BLINKofaneye.org

Resources

Rebecca Faye Smith Galli: rebeccafayesmithgalli.com

Stay Connected: Subscribe, leave a review, and share this episode with anyone interested in advocacy for SCI funding!

BLINK of an Eye® Podcast is sponsored by BLINK of an Eye® Non-Profit:

A non-profit which is an essential national resource for Spinal Cord Injury, originating the first SCI Navigator Program in the country for newly injured SCI Families by SCI Families as an essential national resource for Spinal Cord Injured families in the first days, weeks and months of SCI crisis when life turns upside down and few medical teams in the US have SCI expertise or lived experience. They bring essential support, connections, life expertise and resources. BLINK of an Eye non profit deploys a rapid response HEAL Team for ICU bedside support to create an Extraordinary Experience despite the devastation for SCI families and a personal SCI Navigator for 24/7 support in the first 90 days and throughout the Miracle Year. BLINK of an Eye non profit also provides a Multidisciplinary Wrap Around Team and SCI Expert Medical Panel. Stay tuned for their launch of a National Digital Resource Library, the SCI PLAYBOOK, chocked full of essential SCI information and trauma informed responses for the first hours, days and months after injury. To find out more, get involved, or make a donation, visit www.BLINKofaneye.org.

Blink of an Eye is sponsored by Baltimore Mediation:

To find out more about cutting edge conflict transformation skills courses to learn relational conflict theory and advocacy, mediation interventions and support for leaders and anyone navigating or facilitating difficult situations, conflict, or trauma, visit the website www.BaltimoreMediation.com and register for nationally certified 40 hour courses, including the Enneagram of personality for mediators to know themselves to stay neutral while offering opportunity for other’s empowerment.

To find out more about Louise visit: www.BlinkofanEye.org, www.BaltimoreMediation.com, www.BeingRelational.com

Macrophages and the Battle for SCI Repair with Dr. John Gensel

What happens when the cells sent to heal the body after a bodily trauma decide to stick around, becoming a permanent roadblock to recovery, as they do in acute SCI? Is it possible to reprogram the immune system to stop standing guard over the damage and instead open the pathway for repair?

Louise sits down with Dr. John Gensel, a neuroscientist and the Director of the Spinal Cord and Brain Injury Research Center at the University of Kentucky. John has dedicated his career to the microscopic world of macrophages—the body's internal healing cells—and the mystery of why they behave so differently in the spinal cord than anywhere else in the human body. He shares how his lab is working to flip the switch on chronic inflammation, looking for ways to turn a person's own biology from a roadblock back into a healing and repair agent, and an ally to recent NVG-291 breakthroughs. Stay tuned as they explore the cellular frontier of SCI science and what it means for the future of personalized recovery.

#BeginAgain #HopeforEverything

Be part of supporting BLINK of an Eye nonprofit as we support SCI families in crisis and advance science. Give $25 today! www.BLINKofaneye.org

Resources

John Gensel: https://medicine.uky.edu/users/jcge224

Stay Connected: Subscribe, leave a review, and share this episode with anyone interested in advocacy for SCI funding!

BLINK of an Eye® Podcast is sponsored by BLINK of an Eye® Non-Profit:

A non-profit which is an essential national resource for Spinal Cord Injury, originating the first SCI Navigator Program in the country for newly injured SCI Families by SCI Families as an essential national resource for Spinal Cord Injured families in the first days, weeks and months of SCI crisis when life turns upside down and few medical teams in the US have SCI expertise or lived experience. They bring essential support, connections, life expertise and resources. BLINK of an Eye non profit deploys a rapid response HEAL Team for ICU bedside support to create an Extraordinary Experience despite the devastation for SCI families and a personal SCI Navigator for 24/7 support in the first 90 days and throughout the Miracle Year. BLINK of an Eye non profit also provides a Multidisciplinary Wrap Around Team and SCI Expert Medical Panel. Stay tuned for their launch of a National Digital Resource Library, the SCI PLAYBOOK, chocked full of essential SCI information and trauma informed responses for the first hours, days and months after injury. To find out more, get involved, or make a donation, visit www.BLINKofaneye.org.

Blink of an Eye is sponsored by Baltimore Mediation:

To find out more about cutting edge conflict transformation skills courses to learn relational conflict theory and advocacy, mediation interventions and support for leaders and anyone navigating or facilitating difficult situations, conflict, or trauma, visit the website www.BaltimoreMediation.com and register for nationally certified 40 hour courses, including the Enneagram of personality for mediators to know themselves to stay neutral while offering opportunity for other’s empowerment.

To find out more about Louise visit: www.BlinkofanEye.org, www.BaltimoreMediation.com, www.BeingRelational.com