Episodios

  • Slowing the Clock: Longevity Science Meets Alzheimer’s Prevention

    Slowing the Clock: Longevity Science Meets Alzheimer’s Prevention
    Mar 19 2026
    How fast are you really aging, and what could that mean for brain health? Aladdin H. Shadyab, Ph.D., explores the gap between chronological age and biological age, and why that difference matters for long-term health. Shadyab describes tools that use information from blood to estimate how quickly the body is aging, including approaches that look beyond the body as a whole to consider aging in specific systems. He connects faster biological aging with higher risk for age-related disease and declines in physical and cognitive function, and discusses how blood-based biomarkers may offer earlier signals of processes linked to Alzheimer’s disease. Shadyab also highlights lifestyle and treatment findings that may support healthier aging and longer survival. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41073]
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    51 m
  • Circadian Clocks - How To Optimize Your Health

    Circadian Clocks - How To Optimize Your Health
    Dec 29 2025
    How you time light, meals, and sleep can reset your internal clock. Satchidananda Panda, Ph.D. explains why morning light sharpens alertness, evening dimness protects melatonin, and consolidated sleep supports brain “detox.” Clear, practical takeaways you can use tonight and tomorrow morning. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41206]
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    14 m
  • An Ideal Circadian Day

    An Ideal Circadian Day
    Dec 29 2025
    Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, describes what the ideal circadian rhythms of a day look like. Dr. Panda explains that keeping daily light, meals, movement, and sleep in step with the body’s internal clock supports alertness, metabolism, and recovery. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41210]
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    9 m
  • How Much Light Is Healthy?

    How Much Light Is Healthy?
    Dec 22 2025
    How much exposure to daylight is recommended for optimal health? Satchidananda Panda, Ph.D., Salk Institute, answers this question and many more on the therapeutic nature of light. Dr. Panda also discusses indoor lighting considerations in order to simulate day/night cycles. Dr. Panda explains that the use of lighting isn't just for safety and convenience but also for one's health. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 41208]
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    8 m
  • Resilience and Healthy Longevity with Anthony Molina

    Resilience and Healthy Longevity with Anthony Molina
    Dec 12 2025
    Biological resilience underpins healthy aging, and Anthony Molina, Ph.D., investigates how people resist, adapt to, and recover from age-related stressors. Molina defines three domains of resilience linked to aging and studies “life course” resilience using the Rancho Bernardo Study, a longitudinal cohort that starts in 1972 and tracks cognitive, sensory, physical function and comorbidities. His group analyzes trajectory scores from tasks such as the trail-making test and examines thousands of blood molecules to identify patterns that distinguish exceptionally resilient participants. Laboratory experiments show how age-related molecular profiles relate to mitochondrial function and ATP production. Molina’s team also tests behavioral and nutritional interventions in rigorously designed clinical studies, combining molecular biomarkers of biological age with measures of physical performance, cognition, sensory abilities, and mental well-being. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40958]
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    22 m
  • Circadian Rhythm and Intermittent Fasting for Healthy Lifespan - LEE Tuh-Fuh and Ruby LEE Wang Zu-Ming Endowed Lecture

    Circadian Rhythm and Intermittent Fasting for Healthy Lifespan - LEE Tuh-Fuh and Ruby LEE Wang Zu-Ming Endowed Lecture
    Nov 7 2025
    Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, explains that keeping daily light, meals, movement, and sleep in step with the body’s internal clock supports alertness, metabolism, and recovery. Panda notes that evening light and late eating can make it harder to fall asleep and may work against healthy glucose control, while thoughtful timing of activity can improve energy and rest. He highlights that when we take medicines matters because the body’s response changes across the day. Travel and shift work challenge these rhythms, but simple habits with light exposure, meal timing, and sleep can ease the strain. Panda also describes ongoing efforts testing practical routines, including limited daily eating windows paired with light and activity strategies. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40733]
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    1 h y 28 m
  • Mental Health and Resilience

    Mental Health and Resilience
    Oct 24 2025
    Psychological resilience in later life examines how older adults adapt after adversity and cultivate everyday practices that sustain well-being and purpose. Elizabeth W. Twamley, Ph.D., introduces and guides a discussion on mental health and resilience among older adults. Ellen E. Lee, M.D., characterizes resilience as dynamic learning oriented toward flourishing and urges a low threshold for seeking help when symptoms overwhelm daily routines. Sidney Zisook, M.D., presents grief as adaptation to loss, distinguishes acute from integrated grief, and explains how intense waves of emotion gradually become less frequent and more manageable; he views psychedelic therapies as promising but not ready for routine treatment. Marti E. Kranzberg shares practical approaches that include mindfulness, journaling, gratitude, movement, sleep, pain management, creative arts, time in nature, community, and purpose. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40963]
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    43 m
  • Cognitive Health and Resilience

    Cognitive Health and Resilience
    Oct 18 2025
    Cognitive resilience grows from small, consistent habits that keep the brain adaptable. Fadel Zeidan, Ph.D., frames mindfulness as mental training that improves attention, processing, and the way people relate to pain. Erin E. Sundermann, Ph.D., underscores modifiable pathways to healthier aging, highlighting movement, social connection, hearing support, and lifelong learning as mutually reinforcing drivers of brain health. Raenne C. Moore, Ph.D., centers practical strategies that translate into daily life, including routines, planned breaks, reducing distractions, and attending to anxiety or depression. Carolyn Dunmore, an older adult community Mmmber, exemplifies resilience through steady activity, purposeful community roles, faith, self-compassion, and the “use it or lose it” mindset. Together, Zeidan, Sundermann, Moore, and Dunmore point to a clear theme: everyday practices accumulate to support memory, attention, and well-being as people age. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40962]
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    44 m