In this episode of Kidney Commute: Pitstop, we explore key insights from the upcoming KDOQI Commentary on the 2025 KDIGO Clinical Practice Guideline for autosomal dominant polycystic kidney disease (ADPKD). Host Anna Gaddy is joined by Dr. Neera Dahl and Dr. Terry Watnick to discuss how the updated recommendations differ from prior guidance and what they mean for real world practice in the United States. The conversation highlights advances in genetic testing, practical considerations for implementing tolvaptan therapy, and emerging therapies on the horizon. Tune in for actionable takeaways to support clinical decision making and improve care for patients with ADPKD.

Access the commentary here: https://www.ajkd.org/article/S0272-6386(26)00003-X/fulltext

Hosted by Dr. Sam Kant, this Kidney Commute: Pit Stop episode explores the Cerebronephrology region of NephMadness 2026 and the emerging concept of the brain–kidney axis. Drs. David Drew and Colton Jensen examine how chronic kidney disease and ESKD with dialysis contribute to cognitive impairment—an underrecognized complication affecting a large proportion of patients. From early microvascular injury, albuminuria, and hypertension in CKD to cerebral hypoperfusion, ischemia, and structural brain changes during dialysis, this discussion highlights the bidirectional relationship between kidney and brain health. Join us as we unpack where brain injury begins and what this means for earlier recognition and improved patient care.

This podcast explores the critical role of oral health in kidney transplant eligibility and outcomes. Through an interprofessional discussion, learners will examine how oral health impacts infection risk, transplant readiness, and long-term success. Notably, this episode features the valuable perspective of a dentist, highlighting the importance of integrating dental expertise into transplant care. Practical strategies for prevention, care coordination, and addressing access barriers will be highlighted to support patient-centered transplant care.