The novel's primary setting is Vatican City, the heart of the Roman Catholic Church. Robert Langdon and Vittoria Vetra navigate through iconic locations within this sovereign city-state, including St. Peter's Basilica, the Sistine Chapel, and the Vatican Museums. The narrative also extends into the broader cityscape of Rome, where the protagonists explore historic churches, piazzas, and monuments as they follow the “Path of Illumination."

Beyond Italy, the story begins at CERN (European Organization for Nuclear Research) in Geneva, Switzerland. This cutting-edge scientific facility serves as the starting point for the thriller, symbolizing the tension between faith and science that permeates the novel. The contrast between the ultramodern CERN and the centuries-old Vatican City underscores the book's themes of tradition versus progress.

Characters

• Robert Langdon: Harvard symbologist and the protagonist. He is called to CERN to investigate a murder and becomes embroiled in a plot against the Vatican.

• Vittoria Vetra: CERN scientist and daughter of the murdered Leonardo Vetra. She assists Langdon in his investigation and search for the antimatter in Rome.

• Camerlengo Carlo Ventresca: The late Pope's chamberlain. 

• Hassassin: The sadistic killer hired to murder the preferiti cardinals. 

• Maximilian Kohler: Director of CERN who initially calls Langdon for help and uncovers crucial evidence.

• Cardinal Saverio Mortati: Dean of the College of Cardinals who oversees the papal conclave. 

• Commander Olivetti: Head of the Swiss Guard who assists in the search for the antimatter. 

• Leonardo Vetra: CERN scientist and priest who creates the antimatter. 

• Gunther Glick and Chinita Macri: A BBC reporter and camerawoman who cover the events unfolding at the Vatican.

• Lieutenant Chartrand: A young Swiss Guard who plays a role in the final confrontation and resolution.

Quick facts

• Angels & Demons was published in 2000, three years before Dan Brown's more famous novel, The Da Vinci Code.

• Angels & Demons introduces the character of Robert Langdon, who becomes the protagonist of several subsequent Dan Brown novels.

• Angels & Demons spent 144 weeks on The New York Times bestseller list.

• The ambigrams featured in the book were created by real-life typographer John Langdon.

• The novel's plot takes place over a 24-hour period.

• CERN, the European Organization for Nuclear Research, is featured prominently in the story.

• Angels & Demons sparked controversy for its portrayal of the Catholic Church and the Illuminati.

• Angels & Demons mixes fact and fiction, leading CERN to publish a FAQ page addressing scientific inaccuracies. In 2009, A&E released a documentary, Angels and Demons Decoded. 

• A film adaptation directed by Ron Howard and starring Tom Hanks was released in 2009.

• Despite being the first book in the Robert Langdon series chronologically, Angels & Demons was adapted into a film after The Da Vinci Code.

About the Author

Dan Brown is a bestselling American author known for his thriller novels, particularly the Robert Langdon series. Born in 1964 in New Hampshire, Brown grew up on the campus of Phillips Exeter Academy where his father taught mathematics. After graduating from Amherst College, he initially pursued a career in music before turning to writing full-time in 1996.

Brown's breakthrough came with his fourth novel, The Da Vinci Code, published in 2003. The book became an international phenomenon, selling over 80 million copies worldwide and inspiring a successful film adaptation. His other popular works include Angels & Demons, The Lost Symbol, Inferno, and Origin—all part of the Robert Langdon series featuring the Harvard symbologist solving complex mysteries often involving history, art, religious icons, and conspiracy theories. His books have been translated into 57 languages and sold over 200 million copies.

Beyond his literary success, Brown has engaged in philanthropic efforts, including donations to his alma maters Phillips Exeter Academy and Amherst College. He has also faced legal challenges, successfully defending against multiple copyright infringement claims related to The Da Vinci Code. He continues to write and remains one of the world's most commercially successful authors.