Our heroine Alice is catapulted, by a succession of terrifying events, on to an extraordinary journey to find the reincarnated soul of her lost and beloved brother. To aid her, she is given a magical box with six mysterious clues written in different languages, the answers to which will complete a crossword puzzle. Alice is hampered by suffering from a terrible and fatal disease, currently wiping out most of her generation in Britain, which gives her only a few months to live.
Three families are forever affected when their lives intertwine in unexpected ways, and they are forced to face their inner and outer demons. A detective is linked by his obsession with the killer he is searching for: a figure seemingly elusive but strangely present.