Before and since its official closure in 1985, historic US 66 became associated with the deserts, Indians, and cowboys of the Southwest; the "Okies" of the Great Depression; and the millions of vacationers who took to the highway in their streamlined automobiles and found adventure on the open road from the late 1940s to the 1970s.
"What? Rt. 66 is closed? *sniffle*"