It's 1945 and, as the troops begin to return home, the inhabitants of London attempt to put their lives back together. For 25-year-old Millie, a qualified nurse and midwife, the jubilation at the end of the war is short-lived as she tends to the needs of the East End community around her. But while Millie witnesses tragedy and brutality in her job, she also finds strength and kindness. And when misfortune befalls her own family, it is the enduring spirit of the community that shows Millie that even the toughest of circumstances can be overcome.
Nurse Connie Byrne has lived and worked through the Second World War, has celebrated its ending with friends and patients in the East End of London and is now enjoying a fresh new chapter in her life and looking forward to her wedding. But, as many a young bride-to-be has proved, the path of true love never runs smooth.... Connie's busy professional life and the characters who are her patients serve to give her a much-needed sense of perspective.
Connie Byrne, a nurse in London's East End working alongside Millie Sullivan from Call Nurse Millie, is planning her wedding to Charlie Ross, set to take place as soon as he returns from the war. But when she meets him off the train at London Bridge, she finds that his homecoming isn't going to go according to plan. Connie's busy professional life, and the larger-than-life patients in the district, offer a welcome distraction, but for how long?
Nurse Millie Sullivan is now Nurse Millie Smith, having married aspiring MP Jim Smith. The war has ended and the NHS has just come into action, so the nurses are busier than ever as the community realise that they no longer have to pay for the services. Minor ailments need attention, babies need to be helped into the world and some of the larger-than-life characters need keeping in line so Millie has enough drama to deal with without having to deal with more from home.