For many people, a diet with an "inverted pyramid" focused on vegetables, fruits and whole grains is de rigueur. I'm not sure this book will push these people far from that "inverted pyramid". However, for certain classes of these healthy eaters, this book seems to have some well-documented items to think about. High triglycerides and low HDL cholesterol are one class of people the author singles out as potentially having to make dietary changes. Sugar is named as the driving factor behind the triglycerides. The key for the author is the inflammatory effects of weight and sugar on the body. The author cites multiple studies that describe high triglycerides and low HDL as a dangerous condition. His recipe is cut the sugar and preprocessed foods, monitor progress with a number of specific tests, and consider the potential of specific supplements. The author considers this condition more dangerous than high LDL cholesterol yet many doctors would view this type of patient with ambivalence all else being equal. If this describes you and your doctor is not concerned, you may want to read the book and consider making some changes. Another group of folks are folks who consume an imbalance of Omega 6s versus Omega 3 fats. Lots of folks with an under control LDL have some degree of ambivalence with regard to fats. This book tells those folks to pay more attention to the type of fats they consume and considers Omega6 versus Omega 3 to be pretty highly inflammatory. Again this class of person should read the book, read the citations, and think about taking action (which is spelled out in dietary recommendations, tests, and potential supplements).
For healthy eaters who try to manage their health by understanding the impact of diet on the body this book is highly recommended. This book will challenge many preconceptions you might have about the importance of cholesterol and will challenge you to think more deeply about the impact of sugar and inflammation on health. It will also recommend that you study different types of cholesterol than is customary right now. It will give you a list of specific tests that will help you gauge inflammation in your body. It will also recommend a list of supplements that may be effective depending upon your particular situation.
For unhealthy eaters, this book is also highly recommended as it puts a focus on sugar (and processed foods) not so much on fats and cholesterol. While the book is somewhat controversial in that it worries far less on the impact of cholesterol on health, for most folks I know who have unhealthy diets... sugar is their real problem. I believe a focus on sugar... reducing the dependence that many have on sugar is a surer first step to a healthy life than a focus on cholesterol reduction. Not a doctor, not an unhealthy eater... but I believe this book is a must read for these folks.
Bad news is you have to be your own physician. Good news is there are movements like Functional Medicine which offer hope to many of us who have been failed by the system.
The human body is an amazing system. Surprisingly we have very few genes and even fewer genes that make meaningful distinctions among us. Functional medicine offers a way to begin to think about how our genes are interacting with our environment, broadly defined. That broadly defined means hazards as well as diet.
Too many of us have just accepted the "wisdom" of some doctor. Take this pill and you'll be fine. Hey you're an allergy freak, but my allergy shots will desensitize you. Ummm, yeah you're kinda close to metabolic disorder, but a statin will fix that right up. Run harder, longer, accept that your basal metabolic rate is 50-60% of what it should be. It would be comical if it weren't so tragic.
If you love someone whose health is not right or are someone who feels like something just isn't quite right with their health and you want to understand how to think about what might be wrong and how to begin taking healing steps, this book is a great place to start. There is a difficulty because there are so few skilled functional medicine practitioners, but perhaps a dialogue with a trusted open minded physician could enlist an ally. There are likely resources online as well, but caveat emptor. But a better informed patient is more capable of understanding the hazards of different courses of action and weather the blistering criticisms of the big pharma reps (formerly called doctors). This book will give you the tools to be a better informed patient. Some experimentation is also necessary because our genetic codes are all different... so what works for some may not work for you. But you'll be on a more hopeful, optimistic, and empowering journey to restore your health.
Functional Medicine is at a high level an engineering type of systems analysis of the human body. Terry Wahls while under assault from MS, took a functional medicine approach to helping her body fight back against MS. This is notable for many reasons not the least of which are her examples of tenacity, mental strength, and perseverance in extreme adversity. But it is also notable because she trusted her body that was failing her to fix her. Many practitioners, theoreticians, and laypeople are coming to a conclusion that many of today's most troubling diseases are caused by metabolic / mitochondrial dysfunction. Solving metabolic dysfunction was at the root of Dr. Wahl's approach and she initially designed a supplement program to help her mitochondrial become more powerful. As she began to feel better she designed a diet to replace much of her supplement regimen.
So what you are getting in this book is a diet that is aimed at restoration of your mitochondrial power. Many practitioners think this is a strategy that can be successful for diseases such as diabetes, MS, palsy, CFS, etc. Whether you are sick or healthy, you could likely benefit from comparing and contrasting this diet with your own. There is a ton of wisdom built into this diet. Our bodies are all different so dietary "hacking"/"tweaking" is almost always necessary, but this diet would make a great starting place for someone looking to change their current health trajectory.