American Dementia

For decades, researchers have chased a pharmaceutical cure for memory loss. But despite the fact that no disease-modifying biotech treatments have emerged, new research suggests that dementia rates have actually declined in the United States and Western Europe over the last decade. Why is this happening? And what does it mean for brain health in the future?

Tabitha Knicely is overwhelmed with sorrow and exhaustion caring for her beloved great-aunt, whose dementia is getting worse. When her neighbor Marcus Whittington accuses Tabitha of elder neglect, he doesn't realize how his threats to have Aunt Tweet taken away add to Tabitha's pain. Then Marcus gets to know the exuberant elderly lady and sees up close how hard Tabitha is fighting to keep everything together. Tabitha finds herself leaning on Marcus more and more. And he's becoming more than happy to share her burdens.

Terry Pratchett has earned a place in the hearts of listeners the world over with his best-selling Discworld series - but in recent years he has become equally well-known and respected as an outspoken campaigner for causes including Alzheimer's research and animal rights. A Slip of the Keyboard brings together for the first time the finest examples of Pratchett's nonfiction writing, both serious and surreal: from musings on mushrooms to what it means to be a writer (and why banana daiquiris are so important).

Brain diseases such as Alzheimer’s and Parkinson’s affect an estimated one in six Americans and are increasing in incidence as the population ages. In this audiobook, we examine these and other conditions involving the damage and loss of neurons, including other forms of dementia, amyotrophic lateral sclerosis (ALS), chronic traumatic encephalopathy (CTE), and multiple sclerosis (MS).

Until recently, one idea has dominated research in treating Alzheimer’s disease: the amyloid hypothesis. Those therapies have repeatedly fallen short, and in this audiobook we take a look at where that hypothesis stands today. We examine recent research into the spectrum of disease causes, including inflammation and immune dysfunction; cutting-edge treatments, including deep-brain stimulation and magnetic resonance - guided focused ultrasound; as well as lifestyle interventions that can help protect from disease.