What Is Macrophage Activation Syndrome (MAS)?
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What Is Macrophage Activation Syndrome (MAS)?
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Adam Narloch speaks with Dr Randy Cron and Dr Daniella Schwartz about the pathology of macrophage activation syndrome (MAS), including its pathophysiology and relationship to hemophagocytic lymphohistiocytosis (HLH). This discussion addresses why MAS recognition can be clinically challenging and how clinicians may think about MAS in the context of hyperinflammation and rheumatologic disease.
This video features expert clinician discussion and is intended for US healthcare professionals.
Chapters
0:00 - What Is Macrophage Activation Syndrome (MAS)?
5:21 - MAS as a Form of Hemophagocytic Lymphohistiocytosis (HLH)
10:12 - Clinical Outcomes and Urgency in MAS
11:09 - Relationship Between MAS and HLH
18:02 - Diagnosing MAS: Criteria, Workup, and Differential Diagnosis
25:53 - Key Takeaways for MAS Recognition and Diagnosis
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