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This Week in Virology

This Week in Virology

De: Vincent Racaniello
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TWiV is a podcast about viruses - the kind that make you sick.Vincent Racaniello 2022 Ciencia Ciencias Biológicas Historia Natural Naturaleza y Ecología
Episodios
  • TWiV 1267: A cancer vaccine and an mpox treatment
    Nov 2 2025

    TWiV discusses the impact of vaccinating with Gardasil-9 adult women who are human papillomavirus positive or with confirmed squamous intraepithelial lesions, and human monoclonal antibodies that target the monkeypox virus A35 protein which protect against lethal disease.

    Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode
    • Support science education at MicrobeTV
    • Immune 100 live at the Incubator
    • Long tailed macaques are now officially endangered (Science)
    • Iceland now has mosquitoes (npr)
    • Impact of Gardasil-9 on adult women who are HPV+ or SIL+ (Viruses)
    • Human mAbs that protect against mpox disease (Cell)
    • Timestamps by Jolene Ramsey. Thanks!
    Weekly Picks

    Brianne – Civet coffee: The real chemistry behind this bizarre luxury drink
    Kathy – Astronomy photographer of the year awards
    Rich – Katherine Swan Ginsburg Humanism in Medicine Program
    Alan – Parasitic worms can use static electricity to latch onto flies midair
    Vincent – How to get the best night's sleep: what the science says

    Listener Pick

    Bradon – Elevated Access

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    Content in this podcast should not be construed as medical advice.

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    2 h y 2 m
  • TWiV 1266: Clinical update with Dr. Daniel Griffin
    Nov 1 2025
    In his weekly clinical update, Dr. Griffin and Vincent Racaniello ponder the nomination of Casey Means for Surgeon General by President Trump, how mRNA vaccines may enhance effectiveness of check point inhibitor cancer therapies, if viral infection associates with cardiac disease, H5N1 isolation from backyard birds and turkey farms, and the effectiveness of the COVID-19, RSV and influenza vaccines before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, if revaccination with the mRNA RSV vaccine is effective, how effective today's COVID-19 vaccine is for protection against severe disease following infection with current viral variants, where to find PEMGARDA, how to access and pay for Paxlovid, can you be retreated with Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, and contacting your federal government representative to stop the assault on science and biomedical research. Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research)SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature)TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV: TWiV 1265)Viral Infections and Risk of Cardiovascular Disease (Journal of the American Heart Association)Confirmations of Highly Pathogenic Avian Influenza in Commercial and Backyard Flocks (USDA: Animal and Plant Health Inspection Service)Three large turkey farms in Minnesota hit with H5N1 avian flu (CIDRAP)Updated Evidence for Covid-19, RSV, and Influenza Vaccines for 2025–2026 (NEJM) Wastewater for measles (WasterWater Scan)Measles cases and outbreaks (CDC Rubeola)Tracking Measles Cases in the U.S. (Johns Hopkins)Weekly measles and rubella monitoring (Government of Canada)Measles (WHO)Get the FACTS about measles (NY State Department of Health) Measles (CDC Measles (Rubeola))Measles vaccine (CDC Measles (Rubeola)) Presumptive evidence of measles immunity (CDC) Contraindications and precautions to measles vaccination (CDC)Measles vaccine recommendations from NYP (jpg)Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)Deaths following vaccination: what does the evidence show (Vaccine)Influenza: Waste water scan for 11 pathogens (WastewaterSCan)US respiratory virus activity (CDC Respiratory Illnesses)Respiratory virus activity levels (CDC Respiratory Illnesses)Weekly surveillance report: Cliff notes (CDC FluView)ACIP Recommendations Summary (CDC: Influenza)Influenza Vaccine Composition for the 2025-2026 U.S. Influenza Season (FDA)RSV: Waste water scan for 11 pathogens (WastewaterSCan) Respiratory Diseases (Yale School of Public Health)US respiratory virus activity (CDC Respiratory Illnesses)RSV-Network (CDC Respiratory Syncytial virus Infection)Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV)) Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)Safety, Tolerability, and Immunogenicity of Revaccination With mRNA-1345, an mRNA Vaccine Against RSV, Administered 12 Months Following a Primary Dose in Adults Aged ≥50 Years (CID)Vaccine effectiveness of a bivalent respiratory syncytial virus (RSV) pre-F vaccine against RSV-associated hospital admission among adults aged 75–79 years in England (LANCET: Infectious Diseases)Waste water scan for 11 pathogens (WastewaterSCan)COVID-19 deaths (CDC)Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)COVID-19 national and regional trends (CDC)COVID-19 variant tracker (CDC)SARS-CoV-2 genomes galore (Nextstrain)Antigenic and Virological Characteristics of SARS-CoV-2 Variant BA.3.2, XFG, and NB.1.8.1 (bioRxiV)Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans (NEJM)Durability of 2024-2025 COVID-19 Vaccines Against JN.1 Subvariants (JAMA: Internal Medicine)Where to get pemgarda (Pemgarda) EUA for the pre-exposure prophylaxis of COVID-19 (INVIYD)Infusion center (Prime Fusions) CDC Quarantine guidelines (CDC)NIH COVID-19 treatment guidelines (NIH)Drug interaction checker (University of Liverpool)Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)Understanding Coverage Options (PAXCESS) Infectious Disease Society guidelines for treatment and management (ID Society)Molnupiravir safety and efficacy (JMV)Convalescent plasma recommendation for immunocompromised (ID Society)What to do when sick with a respiratory virus (CDC)Managing healthcare staffing shortages (CDC) Anticoagulation ...
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    50 m
  • TWiV 1265: mRNA vaccines make cancer treatment great again
    Oct 26 2025

    TWiV explains studies showing that SARS-CoV-2 mRNA vaccines improve life span of cancer patients on checkpoint immunotherapy, and broad immunity conferred by a vaccine central in A(H5) influenza antigenic space.

    Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

    Subscribe (free): Apple Podcasts, RSS, email

    Become a patron of TWiV!

    Links for this episode
    • Support science education at MicrobeTV
    • Immune 100 live at the Incubator
    • SARS-CoV-2 mRNA vaccines sensitize tumors to checkpoint immunotherapy (Nature)
    • People with some cancers live longer after mRNA vaccines (Nature)
    • Immune checkpoint inhibitors (NCI)
    • Broad immunity from influenza H5 vaccine (Nature)
    • Derek Smith on antigenic cartography (TWiV 99 at 2:53)
    • Letters read on TWiV 1265
    • Timestamps by Jolene Ramsey. Thanks!
    Weekly Picks

    Kathy – Permethrin-treated baby wraps for malaria prevention and Phil Sharp and the Biotech Revolution
    Rich – Lydia Fairchild; Tetragametic Chimerism (NEJM)
    Alan – Warning Signs
    Vincent – radio.garden thanks to Kim!

    Listener Pick

    Jamie – SkyCards by Flightradar24

    Intro music is by Ronald Jenkees

    Send your virology questions and comments to twiv@microbe.tv

    Content in this podcast should not be construed as medical advice.

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    1 h y 51 m
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Science first and yet entertaining.
Wonderful gang full of knowledge and joy for related topics.

Love it!

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I found TWiV through the recommendation of another podcast. Like many I am a post covid follower and I have really appreciated TWiV as a source of current and accurate information. The clinical updates with Dr. Griffin are so useful . Dr Gritting uses language that I, a custodian i.e. not a science professional am able to understand. I find the clinical updates really ease my anxieties because finally I understand what is going on around me. Sometimes the other episodes I struggle to totally follow along but I always finish having learned something I didn't know before listening. Turns out virology and immunology is quite fascinating!

Excellent Source

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You need a background in Bio to enjoy this podcast, but if you are on the in you should have a great time.

Fun team

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The content is really good and always interesting with many great guests. Good job guys!

Very good science podcast!

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I discovered TWiV during 2020 due to the desire for more accurate and unbiased information about the viruses and then stayed for the good and interesting science. I never liked biology before but have found the discussions to be reasons to get interested in not only virology but biology, microbiology, even medicine. Although I don’t understand all the science, to hear the unfamiliar multiple times made them less intimidating and I feel like I am sitting in the same room as the host and guest scientists week after week when different topics are being discussed. The weekly clinical updates are also keeping me well informed about the viruses that we should be aware of in a timely way. Love this podcast and many sister podcasts from microbe.tv

A good thing from the pandemic years

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