The Physiology of RFK Jr.'s Blue Dye

Collaborator: Dr Katherine JohnsIf you don't need to put it in your body, don't put it in your body.These cases are patients who I, or my colleagues have seen. They are de-identified and many instances have been presented in more depth in an academic setting. These videos are not individual medical advice and are for general educational purposes only. I do not give medical advice over the internet.References:A family cluster of nitrite poisoning, Suzhou City, 2013. Western Pac Surveill Response J. 2013 Jul 30;4(3):33-6. https://pmc.ncbi.nlm.nih.gov/articles/PMC3854094/Human safety controversies surrounding nitrate and nitrite in the diet. https://pubmed.ncbi.nlm.nih.gov/22487433/A mitochondrial superoxide theory for oxidative stress diseases and aging. https://pmc.ncbi.nlm.nih.gov/articles/PMC4306659/Proposed mechanism of nitrite-induced methemoglobinemia. https://pubmed.ncbi.nlm.nih.gov/15892615/Methylene Blue. https://www.ncbi.nlm.nih.gov/books/NBK557593/Methemoglobinemia. https://www.ncbi.nlm.nih.gov/books/NBK537317/Methylene Blue in Goldfrank's ToxicologyPriapism. https://www.ncbi.nlm.nih.gov/books/NBK459178/Methylene blue as a means of treatment for priapism caused by intracavernous injection to combat erectile dysfunction. https://pubmed.ncbi.nlm.nih.gov/15198160/Pharmacologically-induced Recreational Priapism: Case Report and Review. https://pmc.ncbi.nlm.nih.gov/articles/PMC7676772/PharmGKB summary very important pharmacogene information for G6PD. https://journals.lww.com/jpharmacogenetics/citation/2012/03000/pharmgkb_summary__very_important_pharmacogene.8.aspxThe Methylene Blue Baby. N Engl J Med 1989;320:1756-1757. Methylene blue as an antidote for poisoning. J Lab Clin Med. 1933;19:166–71.Methylene blue for distributive shock: a potential new use of an old antidote. J Med Toxicol. 2013;9:242–9.A review of methylene blue treatment for cardiovascular collapse. J Emerg Med. 2014;46:670–9.The role of monoamine oxidase inhibitors in depression treatment guidelines. https://pubmed.ncbi.nlm.nih.gov/22951237/FDA to Revoke Authorization for the Use of Red No. 3 in Food and Ingested Drugs. https://www.fda.gov/food/hfp-constituent-updates/fda-revoke-authorization-use-red-no-3-food-and-ingested-drugsMethylene Blue in the Treatment of Poisonings Associated with Methemoglobinemia. https://www.nejm.org/doi/abs/10.1056/NEJM193306012082205Lawmakers Press Amazon on Sales of Chemical. https://www.nytimes.com/2022/02/04/technology/amazon-suicide-poison-preservative.html