Why has America's health secretary RFK Jr fired the head of America's public health body? He says she was taking the Centres for Disease Control and Prevention in the wrong direction. She and her colleagues - who have resigned in protest - say they were uncomfortable following an anti-vax, anti-science direction of travel. Where will the MAHA project leave Americans? Will vaccines dry up? And does it even have Trump's support? We speak to Dr Mandy Cohen, who led the CDC until Trump's inauguration in January.

Later, federal troops are coming onto Chicago's streets - a city described as a "hellhole" by the President despite having a lower murder rate than several cities governed by Republicans. Is Trump trying to create a private army under his control?

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It's not the first time Donald Trump has overreached, but his latest assertion is that he has the right to do whatever he wants. Trump wants total control - of universities, the police and anyone he perceives to be a threat. He's 'fired' Lisa Cook, the first Black woman to serve on the Federal Reserve’s Board of Governors. The FBI have raided John Bolton's home. Are there any signs anywhere of any checks on Trump? Or is America sliding towards a dictatorship?

Later, we're joined by Patrick Gaspard - Obama’s 2008 national political director. He's the informal advisor to Zohran Mamdani, the Democratic Party’s nominee for New York mayor.

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We start with the fallout from the unorthodox, perhaps undignifying diplomatic spectacle at the White House earlier this week. We are a million miles away from any peace deal in Ukraine, let alone any concrete shape of the 'security guarantees' Donald Trump has suggested may hypothetically be offered by the US in the event that Europe puts boots on the ground in Ukraine. And yet, already, prominent MAGA voices are coming forward to sound the alarm about American involvement in another foreign war. What do those warnings mean for how Donald Trump confronts the most pressing global crisis?

Later, Gavin Newsom has clearly irritated the President - and Fox News - with his social media imitation of Donald Trump. He's started TWEETING IN ALL CAPS!! and thanking followers for their attention to this matter. It's a novel approach, and does appear to have boosted his personal ratings as speculation heightens that he's eyeing up the Democratic presidential nomination in 2028. Is it effective? Or is it just a bit cringey? And is he mocking Trump? Or imitating him?

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