The Blood Brain Barrier Conundrum

Until only recently, treating Glioblastoma brain cancer with chemotherapy has not been achievable due to the blood brain barrier. In today’s Bindwaves episode, Dr. Michael Canney walks us through how Carthera developed a revolutionary method to deliver therapeutics to the brain utilizing an ultrasound system. It is well known that the survival rate for Glioblastoma is 1 to 2 years. Surgery tends to be the primary means to combat this horrible disease. To improve these odds, an ultrasound implant is placed in the brain after the surgeon removes the tumor. This implant, or mesh, contains an ultrasound transducer, which when activated during chemo treatments, disrupts the blood brain barrier thus allowing therapeutics to attach to the cancer cells. Join us as Dr. Canney eloquently discusses the history of this treatment, Phase 1 and Phase 2 results, and their hopes for the Phase 3 trial.

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