The Big Unlock Podcast Por Rohit Mahajan & Ritu M. Uberoy arte de portada

The Big Unlock

The Big Unlock

De: Rohit Mahajan & Ritu M. Uberoy
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THE BIG UNLOCK PODCAST is a Healthcare Digital Transformation Podcast. Stay Updated on Healthcare’s Digital Transformation Trends. Featuring C-suite Leaders and Insights on Digital Health Innovation. Explore Emerging Healthcare Technologies with Rohit Mahajan and Ritu M. Uberoy.© 2025 The Big Unlock Podcast
Episodios
  • AI Leadership Starts with a Simplified, Integrated Tech Stack
    Apr 14 2026
    The Big Unlock · Michael Hasselberg, PhD, RN, Chief Transformation and Digital Officer, Nebraska Medicine

    In this episode, Dr. Michael Hasselberg, Chief Transformation and Digital Officer at Nebraska Medicine, makes a compelling case that sustainable digital transformation in healthcare requires more than technology, it demands the right organizational structure. By unifying IT, innovation, and strategy under a single transformation office, health systems can move from isolated pilots to enterprise-wide impact.

    Drawing from his journey across telehealth, mobile apps, VR, and AI, Dr. Hasselberg emphasizes that true transformation is about redesigning systems to deliver the right care at the right time. Nebraska Medicine deploys nearly one new generative AI tool per month, automating capacity management, discharge workflows, and revenue cycle operations. He also highlights the value of real-world innovation units where new technologies are tested with live patients before system-wide deployment.

    Dr. Hasselberg’s most provocative insight: the next frontier of AI readiness isn’t a new technology, it’s application rationalization. He argues that to lead in AI and innovation, health systems must simplify their tech stack. Take a listen.

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    27 m
  • Healthcare Needs Real Disruption, Not Incremental Change
    Apr 7 2026
    The Big Unlock · Dr. Stephen K. Klasko, Executive in Residence, General Catalyst & Board Chair, DocGo, Teleflex

    In this episode, Dr. Stephen K. Klasko, former CEO of Jefferson Health, Executive in Residence at General Catalyst, Board Chair at DocGo, Teleflex, and one of healthcare’s most provocative voices, challenges the industry to rethink its fundamental assumptions and move toward a more sustainable, patient-centered future. He argues that despite years of discussion around value-based care and digital transformation, true disruption has been limited because stakeholders remain unwilling to fundamentally change existing business models.

    Dr. Klasko argues that the healthcare system is broken, fragmented, expensive, and inequitable and that true disruption, like what Uber did to taxis or Amazon to retail, will demand that some players fail. He makes the case that the annual physical visit is a farce, and that continuous health narratives powered by wearables and AI companions are the future of proactive, personalized care.

    On the tech-provider collaboration front, Dr. Klasko identifies – founder ego, misaligned incentives, and EHR-era skepticism as the biggest barriers. He advocates for co-developing solutions, sharing equity, and building genuine partnerships. Dr. Klasko’s message to healthcare leaders is unambiguous: stop turning things around 360 degrees and start making real, uncomfortable changes. Take a listen.

    This guest appearance was facilitated through conversations initiated at Health Tech Summit by Cornell Tech.

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    22 m
  • Autonomous AI Turning Evidence into Action
    Apr 1 2026

    

    The Big Unlock · Dr. Eric Stecker, Co-founder and Chief Medical Officer, Insight Health

    In this episode, Dr. Eric Stecker, Co-founder and Chief Medical Officer at Insight Health, explores how autonomous AI agents are reshaping cardiovascular care and population health in the United States.

    Dr. Stecker draws a critical distinction between autonomous action and autonomous decision-making, arguing that AI can deliver enormous clinical value today by acting autonomously on well-established care protocols, without waiting for fully autonomous diagnostic AI. He highlights that preventable conditions like hypertension and high cholesterol already have decades of evidence behind them; the real gap is in implementation, where AI-powered agents can identify at-risk patients, prompt appropriate prescriptions, and check in on medication adherence by reducing millions of avoidable cardiac events.

    Dr. Stecker emphasizes that clinician involvement, not just advisory oversight, is essential to avoid alert fatigue, documentation overload, and signal-to-noise failures. He states that meaningful AI adoption requires building trust with both healthcare workers and patients, starting with autonomous action today while responsibly advancing toward autonomous clinical decision-making tomorrow. Take a listen.

    This guest appearance was facilitated through conversations initiated at ViVE.

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    25 m
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