Timestamps:

4:09 - Obstacles to innovation in corporates

10:53 - Starting a startup in your 40s

17:00 - Learning to endure pain

19:40 - Financial planning for your startup

27:36 - What if your startup fails?

About Danny Chatziprodromou:

Danny Chatziprodromou is the founder and CEO of REOR20, a company developing the next generation of models providing highly accurate flood hazard information at a significantly lower cost. He holds a PhD in Computational Fluid Dynamics and Mechanical Engineering from ETH. He worked for companies like Swiss Re and SAM Sustainable Asset Management before starting REOR20 in 2017.

The model Danny’s team developed is 100 000 times faster than traditional models, and his realization that the typical models were that simplified was precisely what motivated him to look into the issue. He also claims that his long and uneventful stay in corporate gave him the arrogance needed to believe he could build a business by himself. Reality, as it turns out, was more challenging, but REOR20 managed to be successful regardless.

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Timestamps:

5:20 - Making a business out of free water

8:12 - Competition in the advertising world

10:00 - The decrease in the quality of online advertising

13:09 - Distributing 25K bottles

17:21 - Fundraising through the Swisspreneur Syndicate

About Christoph Bertschy & Gaël Riesen:

Gaël Riesen is a co-founder and the Head of Production/Distribution at Gratiswasser, and his co-founder Christoph Bertschy is the owner of the company. Gratiswasser is a startup placing ads in free water bottles to be distributed in stores, at festivals, cafés and in general around town. They aim to offer companies a cost-effective advertising opportunity that also has a positive impact on the community.

Gaël and Christoph were motivated by a belief that water as a commodity should be free, and by the motivation to make this possible in a market economy: so they decided to use water bottle labels as advertising slots! One of their partners, VIU eyewear, receives the water bottles at their stores and distributes them to customers who drop by.

Placing ads in free water bottles has the benefit of associating the advertisement to the positive feeling of getting free stuff, instead of to the frustrating 30 second wait before you can watch a video on Youtube. It also is a more trustworthy form of advertising than online advertising, which nowadays seems to have become riddled with deepfakes and other shady ecommerce practices.

Gratiswasser is currently fundraising CHF 500K, part of which is being done through the Swisspreneur Syndicate (the 2M mentioned in the episode is a goal for future funding rounds). Click here to learn more about the deal.

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Timestamps:

1:30 - Working for neon

10:22 - Why you should start investing

15:41 - Start investing with findependent

21:44 - Fee structure

36:26 - 5 principles for personal finance

Click here to enjoy three months of NordPass Business for free by using the code “swisspreneur”.

About Matthias Bryner:

Matthias Bryner is the founder of findependent, an app to make investing transparent, easy and beneficial for everyone, regardless of prior knowledge. He holds an MA in Banking and Finance from HSG and interned at Credit Suisse and at neon before starting findependent in 2018.

findependent allows you to open an account online within approx. 15 minutes, easily select an optimally-tailored investment solution and get started with as little as CHF 500. Thanks to their investment app, findependent users are always informed transparently about their investments, earnings and fees.

But first things first: why should you start investing? Basically, because of inflation and the compounding effect. Inflation rises at least 1% or 2% every year, which means that over the long run your savings will be significantly devalued. Similarly, if you start investing now, even if you invest only a little bit each year, this compounds over time and will make a significant difference in your life later on.

findependent encourages its users to invest in ETFs, which is basically like buying a very small percentage of the world economy, instead of investing in a specific stock. This derisks your investment. And even if the numbers in the market fluctuate daily, their overall historical tendency is upwards, so you can rest assured that your money is being put to good use. findependent currently has 12'000 customers.

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Timestamps:

8:49 - Pivoting your marketing

12:17 - The key ingredients for sports recovery

17:43 - Distributing through several channels

23:22 - Importing CONDA to Switzerland

33:25 - Developing crowdfunding momentum

This episode was co-produced with CONDA.ch. If you want to invest in CONDA.ch with preferential conditions, contact them at investor@conda.ch.

About Pedro Schmidt & Linus Gabrielsson:

Pedro Schmidt is the founder and CEO of KaEx, the world’s first sports-recovery drink to significantly reduce the stress hormone. He holds a MSc in Management, Technology and Economics from ETH Zürich, and previously worked for companies like Siemens Management Consulting, Bristol-Myers Squibb and Teva Pharmaceuticals before founding KaEx in 2016.

Linus Gabrielsson is the managing director at CONDA.ch, the leading platform providing Swiss startups access to crowd investment capital as well as community building and campaigning opportunities. He holds a MSc in Technology Management from ETH and previously worked for companies like IBM Business Consulting Services, PwC and HSBC Private Bank before founding CONDA.ch in 2021.

KaEx was the result of many years of research for Pedro, whose undergraduate education is in Pharmaceutical Sciences. He originally branded it as a hangover remedy, and that’s how it began to be sold in pharmacies and at Coop supermarkets. At some point, Pedro and his team started getting messages from people who swore on the benefits of drinking KaEx post-workout. Pedro ignored these messages at first, since as a resource-constrained founder he couldn’t afford to split his focus — but then pro-athletes started contacting him as well, asking if drinking KaEx could be considered doping (which it couldn’t). This made Pedro and his team seriously question whether they should pivot their product’s branding and focus. They eventually did do so, and nowadays KaEx is known primarily as a sports drink, though it is of course also useful for hangovers or after a particularly stressful day.

In 2021, CONDA.ch was already one of the most successful crowdfunding platforms in Austria and Germany. Rather than try to compete with them, Linus and his co-founder Christian Klumpe decided to strike a franchising deal with their DACH counterparts in order to bring CONDA to Switzerland. As a crowdfunding platform, they focus on startups, SMEs and real estate, and allow users to invest as little as CHF 100. CONDA.ch always runs a 2 week pre-round with preferential conditions open only to VIP investors: that way, when the deal goes public, it never starts at 0, which helps it gain momentum.

KaEx has crowdfunded on CONDA.ch several times.

Timestamps:

5:15 - Having a co-founder pass away

10:33 - Drug resistance and cancer patients

18:24 - Clinical development

23:17 - Raising a series A as a biotech

26:43 - Striking partnerships

Check out the LinkedIn event for our livestream with Aurelio Perucca on May 22nd.

About Stefanie Flückiger-Mangual:

Stefanie Flückiger-Mangual is the co-founder and CEO at TOLREMO Therapeutics, a biotech startup on a mission to prevent non-genetic cancer drug resistance. She holds a PhD in Molecular and Translational Biomedicine from ETH and worked there as a Postdoctoral Researcher before starting TOLREMO in 2017 together with Wilhelm Krek, who has since tragically passed away.

There is no shortage of cancer therapies in biotech and medtech, and one common problem that they face is drug resistance: even if a certain therapy is at first successful in reducing the tumor’s size, patients sometimes develop a resistance to it, whether it be genetic or non-genetic, and the therapy stops working. To use a tech metaphor, genetic drug resistance is akin to a hardware problem, whereas non-genetic drug resistance is more similar to a software malfunction. Since non-genetic resistance is much more dynamic, it’s harder to measure and combat — this is what Stefanie and her fellow researchers have been studying for the past few years. They discovered a pivotal mechanism that governs critical transcriptional resistance pathways, i.e., that stops cancer drug resistance as it emerges without interfering with cancer-unrelated pathways.

TOLREMO recently completed its Series A financing, bringing their total amount raised to USD 39M. Their ultimate goal is to prove the efficacy of their treatment and join forces with a larger pharma company.

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Timestamps:

1:45 - Leaving Batmaid for Holistiq

8:52 - Holistiq’s incredible traction

10:05 - The healthcare market

12:10 - Hiring the right people as a startup

13:58 - Raising funds through the Swisspreneur Syndicate

Click here to apply to join our 2024 Lausanne Scaleup Cruise.

About Eric Laudet:

Eric Laudet is the founder and CEO of Holistiq, a startup offering an organic and personalized approach to healthcare which aims to solve health issues at their root, instead of just treating symptoms. Eric holds a master’s degree in Business Management from HEC Paris, and previously co-founded Batmaid and was active for 6 years as its CFO before starting Holistiq in 2022.

Holistiq’s approach combines different healing systems to create natural therapies that are tailored to the needs of patients and backed by research, lab tests and data science. They operate a digital platform and urban health centers with a team of complementary medicine therapists, life & health coaches, nutritionists, and functional medicine doctors, to support the healing of chronically-ill patients and help others find optimal health.

During his chat with us, Eric placed Holistiq’s offering between that of regular doctors, which are in his opinion currently better suited to treat acute disorders than chronic disorders, and the offering of longevity startups, which often only help people with the prevention of disease, not with treating existing diseases. He also criticized longevity startups for sometimes tracking biomarkers which do not move the (health) needle, merely for publicity’s sake. Eric added that Holistiq’s offering is partly covered by health insurance, and is meant for the masses, not just for the wealthy few.

Despite being in operation for only 2 years, Holistiq already has impressive traction: CHF 400K in revenue (with a 50% gross margin), 1000 paying patients, and both offline and online offerings. They are currently raising a seed round of CHF 3M, CHF 250K of which they’ve already raised from business angels, and CHF 250K which they expect to raise through the Swisspreneur Syndicate. The remaining CHF 2.5M will be raised from healthtech VCs. Click here to learn more about the deal.

Timestamps:

1:42 - The food industry

11:20 - Ensuring quality across suppliers

16:41 - Maintaining a high shelf life

26:10 - Markets Planted is tackling next

33:20 - Small pivots over time

About Pascal Bieri:

Pascal Bieri is the co-founder of Planted, a startup creating healthy plant-based meat alternatives. He holds an MA in Informations-, Media- and Technology Management from the University of St Gallen, and previously worked in companies like SweetWorks Confections and DeepTech Capital AG before starting Planted in 2019. He also co-founded the Green Liberal Party in Lucerne when he was 21, but the slowness of politics soon dissuaded him from getting further involved.

So what’s wrong with livestock farming?

From a cold, technocratic point of view, not taking into account the environment, animal well-being or workers’ rights, current livestock farming practices were great for the meat industry, since they allowed it to achieve a fantastic production ration, super efficient supply chains, pay almost no taxes and deliver very low margins to everyone involved. Meat became cheap and accessible to almost everyone. However, this came at the cost of…

• Destroying acres and acres of land to build livestock operations;

• Establishing intensive monoculture farming operations which deplete soils of nutrients in order to feed livestock, which requires 25x the amount of those crops than we do to meet their nutritional needs;

• Emitting 14.5% of all greenhouse gas emissions, which is about the same as the amount emitted by the entirety of the transportation system.

‍

Planted makes meat alternatives mainly out of pea protein, which can be grown locally and gives great taste. In 100 g of planted.chicken Nature, for example, there is 23.7 g of protein, which is about the same amount as found in conventional chicken meat. planted.chicken Nature consists of no more than four natural ingredients and a healthy portion of vitamin B12. What scares Pascal in the meat alternative market is not companies trying to produce equally healthy and tasty alternatives, but the companies making unhealthy products that taste terribly, which deter people from ever trying out a vegan product again.

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Timestamps:

3:49 - Startups & IP rights

8:56 - Trademarks and patents

17:45 - Startups getting into IP trouble

25:58 - Protecting your IP globally

33:34 - Open source code

This episode was produced in collaboration with startup days, taking place this year on May 30th 2024. Click ⁠here⁠ to purchase your ticket.

About Matthias Kaech & Adrian Riedo:

Adrian Riedo is the founder and owner of RNX, short for Riedo Networks, a provider and distributor of energy monitoring and control solutions which began back in 2005. Matthias Kaech is a Senior IP Trainer at the Institute for Intellectual Property.

Matthias and Adrian have a few IP recommendations for startup founders:

• Never discuss (the intricacies of) your (tech) invention in public. Once the information is leaked, your patent may be ruined;

• Look into the different types of IP protections and figure out which one is best for your company: patents for tech, trademarks for services, copyright/trademarks for software/apps, design rights for luxury products, etc..

• If you want to file for a trademark, the only register you have to be in is the National Trademark Register. Any other registers that contact you are private registers, and you’re not required to be listed on them, so don’t waste your money;

• Figuring out IP protection early on will give investors a positive view of your startup, partially because they know your product/service is protected, and partially because they see you took the trouble to make sure you had freedom to operate, and this shows competence;

• You have to apply for IP protection in each and every country. As a resource-constrained startup, you should think about which countries are your main markets and where your main competitors operate, so that you don’t waste money.

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