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We live in strange days... The research field is facing a very challenging situation (born out of some very stupid decision making). In this ChUG episode, Melissa Leone - sales expert extraordinaire, VP of all things complicated, and now the very best core director in the land, helps David come up with a plan to reduce expenses by 10%, or increase revenues by 10%. Then we end up creating a Chicago-based marketing effort.

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Here it is! The debate that will settle this business of post acquisition adjustment of your unmixing matrix. Is it an appropriate thing to do? Or will applying manual compensation to your data send you to the 9th circle of hell (the one with the puppy stuck in ice)? So fine, my awesome guests Florian Mair and Rui Gardner do not come up with the final answer during this very insightful discussion. But I think the discussion will get us flow cytometry nerds look at the issue in a different way, and offers valuable insights for anyone struggling with incomplete correction of their spectral overlap!

Two notable shoutouts:

• Colibri Cytometry blog: https://www.colibri-cytometry.com/blog
  
  
• Flow Discord Channel: / discord
  
  

The Panel Design Workshop in Zurich will be from January 26-30 2026. Stay tuned for details and registration!

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To Buy or to Lease? Finding funds for the purchase of flow cytometry equipment in your core facility can be challenging. In this first installment of the Tools of the Trade podcast, we discuss the leasing option offered by First American with Andrew Card and Nick Borkowski.

RAIFCA's Tools of the Trade podcast highlights lesser-known tools available to flow cytometry core facility staff and users. We do not necessarily endorse the products discussed; our goal is to help listeners gain a better understanding of them.