In this episode of the Neurocritical Care Society Podcast Masterclass series, hosts Stephan Mayer, MD, FCCM, FNCS, and Jon Rosenberg, MD, are joined by Hooman Kamel, MD, MS, professor of neurology at Weill Cornell Medicine, to discuss how clinical trials take shape in practice. Dr. Kamel reflects on his path into research, the importance of strong mentorship and what it takes to grow from early-stage projects to large multicenter trials.

Their conversation explores practical aspects of trial design in neurocritical care, including building robust data sets, leveraging EMR-based tools, designing pragmatic studies and fostering collaboration across institutions. They also discuss the Arcadia trial and the broader mindset required to stay engaged in research, even when results do not go as expected.

The views expressed on the NCS Podcast are solely those of the hosts and guests and do not necessarily reflect the opinions or official positions of the Neurocritical Care Society.

In this episode of the NCS Podcast Perspectives series, Nicholas Morris, MD, welcomes Tom Lawson, PhD, ACNP-BC, FNCS, lead advanced practice provider at The Ohio State University, as a recurring co-host who will bring APP perspectives to future NCS podcast discussions. Lawson reflects on his path into neurocritical care and explains how the specialty's unique blend of neurologic focus and broad ICU medicine continues to keep him engaged.

He also discusses persistent gaps in APP onboarding and mentorship, highlighting why the NCS Advanced Practice Orientation Bundle is a key resource for programs integrating new APPs into neurocritical care teams. Lawson previews upcoming APP-focused education initiatives, including planned masterclasses on EEG and MRI interpretation, and shares insights on balancing the need for standardized practices with the flexibility required across different institutions.He closes with a call for deeper APP engagement within NCS, from membership to committee involvement, to further strengthen collaboration across the field.

The views expressed on the NCS Podcast are solely those of the hosts and guests and do not necessarily reflect the opinions or official positions of the Neurocritical Care Society.

In this episode of the NCS Podcast Hot Topics series, host Richard Choi, DO, FNCS, is joined by Wendy Ziai, MD, professor of neurology and critical care medicine at Johns Hopkins University, to discuss the article "Prophylactic Anti-Seizure Medication in Patients with Lobar Intracerebral Hemorrhage", recently published in Neurocritical Care.

Their conversation explores the ongoing debate surrounding prophylactic antiseizure medication use in patients with lobar intracerebral hemorrhage. They review current guideline recommendations, highlight limitations in the existing evidence and consider the challenge of balancing seizure prevention with the risk of adverse effects.

Dr. Ziai reviews key findings from prior trials as well as the featured study, which demonstrated lower rates of early seizures among patients who received prophylaxis. She also addresses questions related to patient selection, nonconvulsive status epilepticus and long-term cognitive outcomes. The discussion further considers the role of continuous EEG monitoring in the first 48 hours and how future study designs may help clarify which patients, if any, are most likely to benefit.

The views expressed on the NCS Podcast are solely those of the hosts and guests and do not necessarily reflect the opinions or official positions of the Neurocritical Care Society.