A vaccine capable of protecting against multiple strains of avian influenza virus may be a step closer, according to new research. The H5 subtype of avian influenza viruses has spilled over into mammals and is particularly concerning to researchers due to the risk of them evolving to cause another pandemic. But because there are multiple variants of these viruses, it has been hard to pre-prepare vaccines. Now, a team have used information on how these viruses evolved over time to design a vaccine that in animal studies provided protection against different H5 strains. They hope their approach could be applied to create stockpiles of vaccine that could be used in the event of a pandemic, regardless of the strain that causes it.

Research Article: Kok et al.

Making muon beams without a huge particle accelerator — plus, the bats hunting migrating birds in mid-air.

Research Highlight: Portable muon beam could accelerate archaeology scans

Research Highlight: European bats capture migrating birds and eat them on the wing

A new search engine that can sift through the staggering volumes of biological data, and the multiple failings revealed by an assessment of 25 years of carbon offsetting data.

Nature: ‘Google for DNA’ brings order to biology’s big data

The Guardian: Carbon offsets fail to cut global heating due to ‘intractable’ systemic problems, study says​​​​​​​

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Stereotyped assumptions about women’s ages and their perceived job suitability are enhanced by Internet imagery, according to new research. A study of hundreds of thousands of online images shows that women appear younger than men. This stereotype extends to the jobs that people perceive women do, with men being associated with roles such as CEO or head of research, while women were linked to occupations like cook or nurse. The research shows that these biases have been embedded into the training data for AI models and could affect future hiring. The researchers caution that society is at risk of creating a ‘self-fulfilling prophecy’ where these stereotypes shape the real world.

Research Article: Guilbeault et al.

News and Views: Distorted representations of age and gender are reflected in AI models

A very hungry planet — plus, how climate change is leading to larger trees in the Amazon.

Research Highlight: ‘Rogue’ planet is fastest-growing ever observed

Research Highlight: Trees of the Amazon are becoming even mightier

Thirty years ago, astronomers announced the discovery of the first exoplanet around a Sun-like star, sparking a renewed passion into spotting these planets that lie beyond our Solar System. In celebration, Nature asked researchers to tell us about their favourites.

News: These alien planets are astronomers’ favourites: here’s why

Hear the music of a distant planetary system

Flora Graham from the Nature Briefing joins us to talk about the winners of this year’s science Nobel prizes.

Nature: Medicine Nobel goes to scientists who revealed secrets of immune system ‘regulation’

Nature: Groundbreaking quantum-tunnelling experiments win physics Nobel

Nature: Chemistry Nobel for scientists who developed massively porous ‘super sponge’ materials

Nature: Will AI ever win its own Nobel? Some predict a prize-worthy science discovery soon

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Research suggests that ancient viral-DNA embedded in the human genome is playing a key role in early embryo development. Around 8% of our genome consists of endogenous retrovirus DNA — the remnants of ancient infections, but knowledge of their activity is limited. Now, a team show that these sequences are required for the correct development of lab-derived embryo analogues, and for the switching on of human-specific genes.

Research Article: Fueyo et al.

News and Views: Ancient viral DNA in the human genome shapes early development

Longer whale mothers are more likely to give birth to daughters — plus, how the stink of the corpse flower waxes and wanes to attract pollinators.

Research Highlight: Big mother whales have more daughters than sons

Research Highlight: Corpse flowers waft out stinky compounds as fast as landfills do

Researchers have developed a way to use heat to recharge DNA-based computer circuits, which could help overcome one of the stumbling blocks preventing this technology from being scaled up. Although DNA strands have been used to perform computational tasks for some time, current methods can run out of energy or build up waste products, preventing their continued use. Now, using just heat a team have demonstrated a reuseable neural network based on DNA. They hope that ultimately this could be a step in the development of bigger and more powerful DNA computers that could be used to power targeted clinical therapies.

Research Article: Song & Qian

A one-time gene therapy for Huntington’s disease show promise at slowing the brain disorder’s progression — plus, how mitochondria throw out ‘tainted’ DNA.

Nature: Huntington’s disease treated for first time using gene therapy

Nature: Mitochondria expel tainted DNA — spurring age-related inflammation

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