MASH Explained: Symptoms, Diagnosis, Testing, and What Patients Need to Know

MASH—metabolic dysfunction–associated steatohepatitis (formerly known as NASH)—is a progressive form of fatty liver disease that often develops silently, without obvious symptoms. Many people don't realize their liver is being damaged until the disease has already advanced.

In this episode of the Gastro Girl Podcast, host Jacqueline Gaulin is joined by Dr. Pooja Singhal, a board-certified gastroenterologist, hepatologist, obesity medicine specialist, and founder of the Oklahoma Gastro Health and Wellness Center.

Dr. Singhal explains:

• The difference between MASLD and MASH
• Why MASH is frequently missed or diagnosed late
• Why testing—not symptoms—is the only reliable way to assess liver health
• Who is at risk for developing MASH
• How MASH is diagnosed and what liver testing involves
• Why fibrosis (liver scarring) matters
• Current treatment, prevention, and long-term management strategies
• How early identification can help reduce the risk of cirrhosis and liver cancer

This episode focuses specifically on MASH, the progressive form of fatty liver disease. MASLD is discussed only to help listeners understand how MASH develops and why timely testing matters.

Designed to reduce confusion, raise awareness, and empower patients, this conversation equips listeners with the knowledge they need to have informed discussions with their healthcare providers.

Thank you to Madrigal Pharmaceuticals for supporting this episode.