In this episode of Listen In, see how emerging and global challenges of conducting ethical animal research have led to the 12Rs Framework to guide humane experimental techniques in animal studies and other research areas.

The Principles of Humane Experimental Technique, the 3Rs (Replacement, Refinement, and Reduction), have been the mainstay of humane research involving animals for over fifty years.

However, it is becoming increasingly apparent that to enable high-quality ethical and humane science involving animals, other ethical constructs and issues, for example, research culture, reproducibility, reliability, and responsibility, must also be considered.

The 12Rs Framework brings these different constructs together in a single visual framework. Furthermore, it applies to all areas of scientific research, not just research involving animals.

Watch the full presentation here: https://events.bitesizebio.com/the-12rs-framework-enabling/join

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

In this episode of Listen In, learn more about how the convergence of AI technology and scientific discovery can revolutionize our understanding of biology and disease.

Generating insights into tissue microenvironments is crucial to our understanding of normal and abnormal tissue development, such as during cancer progression.

Spatial biology methods using microscopy and multiplexing techniques have allowed researchers to bring together protein expression profiles and spatial information to dive into the complex biology needed for these insights. However, image analysis of these datasets, especially with high numbers of protein markers and/or large numbers of cells, remains a challenge.

Artificial Intelligence (AI) image analysis has significantly progressed through innovations in deep learning, segmentation, and detection, making it a powerful tool for researchers.

Hear about the latest release of Aivia image analysis software, including AI tools, to help you tackle this challenge in your large 2D multiplexed image datasets.

Watch the full presentation here: https://microscopyfocus.com/elevate-your-research-with-spatial-insights/

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

Glycosylation is a prevalent modification of proteins known to play diverse roles across a wide range of biological processes.

While glycoproteins are widely recognized as key molecular features involved in human health and disease, the analysis of protein glycosylation has historically been hampered by a lack of efficient and simple methods to characterize the analytically challenging glycan structures. Examples include structures exhibiting extensive heterogeneity and subtle isomeric features such as linkage and topological differences.

In this episode of Listen In, Dr. Thaysen-Andersen discusses opportunities and challenges in the burgeoning field of analytical glycoscience.

See the current landscape of glycobiology, learn about innovative analytical methods for N- and O-linked glycosylation profiling from biological specimens, and explore how advances in glycoanalytics enable new insights into human glycobiology.

MilliporeSigma is the U.S. and Canada Life Science business of Merck KGaA, Darmstadt, Germany.

Watch the full presentation here: https://events.bitesizebio.com/unleash-new-biological-insights/join

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/