Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-386

Overview: Physical activity can be a key component of treating depression. In this episode, we discuss the powerful impact of exercise as a nonpharmacologic option, with a spotlight on the benefits of dance. Gain strategies to guide patients on depression therapies and discover why dance stands out among forms of exercise.

Episode resource links:

• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10870815/
• https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10813489/

Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-385

Overview: Through the framework of a case-based scenario, this episode explores both pharmacological and surgical treatment options for obesity. We discuss the efficacy and cost challenges of injectable medications, insurance coverage, and alternative payment solutions. Gain valuable insights into the cost-effectiveness of treatments, including recent research on endoscopic sleeve gastroplasty, to better advise patients.

Episode resource links:

• Haseeb M, Chhatwal J, Xiao J, Jirapinyo P, Thompson CC. Semaglutide vs Endoscopic Sleeve Gastroplasty for Weight Loss. JAMA Netw Open. 2024;7(4):e246221. doi:10.1001/jamanetworkopen.2024.6221
• https://obesitymedicine.org/blog/does-insurance-cover-weight-loss-medication/

Guest: Jillian Joseph, PA-C Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-384

Overview: This episode investigates the inaccurate correlation made between acetaminophen use during pregnancy and an increased risk of developmental disorders, including autism spectrum disorder, in children. Expert faculty discuss the history of these claims, followed by a study evaluating outcomes in children, and emphasize the importance of evidence-based decision-making for patients and clinicians.

Episode resource links:

• Ahlqvist VH, Sjöqvist H, Dalman C, et al. Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability. JAMA. 2024;331(14):1205–1214. doi:10.1001/jama.2024.3172
• Nat Rev Endocrinol. 2021 Dec;17(12):757-766. doi: 10.1038/s41574-021-00553-7

Guest: Aylin Madore, MD, MEd Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-383

Overview: This episode highlights a growing concern—the prevalence of food allergies is on the rise. We underscore the importance for clinicians to help keep vulnerable populations safe through risk reduction strategies as well as the use of medication therapy. Feel empowered to prepare and safeguard patients from adverse reactions to food allergies.

Episode resource links:

• Abrams, E. M., & Becker, A. B. (2015). Food introduction and allergy prevention in infants. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 187(17), 1297–1301. https://doi.org/10.1503/cmaj.150364
• Elghoudi, A., & Narchi, H. (2022). Food allergy in children-the current status and the way forward. World journal of clinical pediatrics, 11(3), 253–269. https://doi.org/10.5409/wjcp.v11.i3.253
• Wood, R. A., Togias, A., Sicherer, S. H., Shreffler, W. G., Kim, E. H., Jones, S. M., ... & Chinthrajah, R. S. (2024). Omalizumab for the Treatment of Multiple Food Allergies. New England Journal of Medicine.
• https://www.foodallergy.org/living-food-allergies/food-allergy-essentials/food-allergy-anaphylaxis-emergency-care-plan
• CDC.gov
• https://acaai.org/

Guest: Mariyan L. Montaque, DNP, FNP-BC Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-382

Overview: Tune in as we discuss the AHA’s newly validated risk calculator designed to assess the risk of developing cardiovascular disease and heart failure in certain patients. We review which risk factor variables were included in the development of this new tool and whether to consider incorporating it in your practice.

Episode resource links:

• https://doi.org/10.1161/CIRCULATIONAHA.123.067626
• The calculator: https://professional.heart.org/en/guidelines-and-statements/prevent-calculator

Guest: Robert A. Baldor MD, FAAFP Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-381

Overview: While the aerosol in e-cigarettes does contain toxicants and carcinogens, since it is not burned like combustible tobacco cigarettes, vaping exposes the user to fewer toxicants and chemicals. Many consider using e-cigarettes for smoking cessation, but evidence has been conflicting. Tune in as we discuss a recent review examining the efficacy of e-cigarettes in aiding smoking cessation and explore potential adverse effects associated with their usage.

Episode resource links:

• Lin, H. X., Liu, Z., Hajek, P., Zhang, W. T., Wu, Y., Zhu, B. C., Liu, H. H., Xiang, Q., Zhang, Y., Li, S. B., Pesola, F., & Wang, Y. Y. (2024). Efficacy of Electronic Cigarettes vs Varenicline and Nicotine Chewing Gum as an Aid to Stop Smoking: A Randomized Clinical Trial. JAMA internal medicine, 10.1001/jamainternmed.2023.7846. Advance online publication. https://doi.org/10.1001/jamainternmed.2023.7846
• Lindson, N., Butler, A. R., McRobbie, H., Bullen, C., Hajek, P., Begh, R., Theodoulou, A., Notley, C., Rigotti, N. A., Turner, T., Livingstone-Banks, J., Morris, T., & Hartmann-Boyce, J. (2024). Electronic cigarettes for smoking cessation. The Cochrane database of systematic reviews, 1(1), CD010216. https://doi.org/10.1002/14651858.CD010216.pub8
• Sanford BT, Brownstein NC, Baker NL, et al. Shift From Smoking Cigarettes to Vaping Nicotine in Young Adults. JAMA Intern Med. Published online November 13, 2023. doi:10.1001/jamainternmed.2023.5239

Guest: Susan Feeney, DNP, FNP-BC, NP-C Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-380

Overview: This episode brings you a comparison of thiazide diuretics, angiotensin-converting enzyme (ACE) inhibitors, and calcium channel blockers on cardiovascular outcomes, stroke, and all-cause mortality. Gain evidence-based insights to help you make informed choices for your patients’ care.

Episode resource links:

• https://pubmed.ncbi.nlm.nih.gov/38048133/#:~:text=JAMA%20Netw%20Open,10.1001/jamanetworkopen.2023.44998

Guest: Jillian Joseph, MPAS, PA-C Music Credit: Richard Onorato

Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-379

Overview: Recent data has shown that colchicine can improve outcomes in patients with known coronary artery disease (CAD), with consideration of colchicine now recommended by the American Heart Association (AHA). Hear valuable insights into the potential benefits and limitations to refine your clinical approach to managing CAD.

Episode resource links:

• Nidorf SM, Fiolet ATL, Mosterd A, et al. Colchicine in Patients with Chronic Coronary Disease. N Engl J Med. 2020;383(19):1838-1847.
• Mohammadnia N, Los J, Opstal TSJ, et al. Colchicine and diabetes in patients with chronic coronary artery disease: insights from the LoDoCo2 randomized controlled trial. Front Cardiovasc Med. 2023;10:1244529. Published 2023 Oct 6.
• Roubille F, Bouabdallaoui N, Kouz S, et al. Low-Dose Colchicine in Patients With Type 2 Diabetes and Recent Myocardial Infarction in the COLchicine Cardiovascular Outcomes Trial (COLCOT). Diabetes Care. Published online January 5, 2024.

Guest: Alan M. Ehrlich, MD, FAAFP Music Credit: Richard Onorato