Best Anti-Aging Skincare for Midlife Women: Estrogen, Retinol & More

In this episode of Menopause Rescue, Dr. Polly Watson sits down with nurse practitioner Kate Willis to cut through the noise of anti-aging skincare. Together, they explore science-backed strategies for midlife skin health, from topical estrogen and retinoids to vitamin C, hyaluronic acid, and sunscreen. Whether you’re curious about estrogen creams, frustrated with retinol irritation, or just want a clear guide to midlife skincare, this episode gives you practical, evidence-based advice to help your skin stay healthy, resilient, and radiant through menopause and beyond. This is the first in a three-part series with Kate covering skin and hair concerns in midlife.

Quotes

• “We’re not trying to make everyone look like Barbie. We want to help people feel comfortable in the skin they’re in.” – Dr. Polly Watson
• “Consistency is key. Skincare is not a six-month project — it’s daily maintenance for the long haul.” – Kate Willis NP-C
• “Both estradiol and estriol creams showed improvements in wrinkles, elasticity, collagen, and hydration — without changing systemic hormone levels.” – Kate Willis NP-C

Connect with Dr. Polly Watson and Kate Willis NP-C

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