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80,000 Hours Podcast

80,000 Hours Podcast

De: The 80 000 Hours team
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The most important conversations about artificial intelligence you won’t hear anywhere else. Subscribe by searching for '80000 Hours' wherever you get podcasts. Hosted by Rob Wiblin, Luisa Rodriguez, and Zershaaneh Qureshi.All rights reserved
Episodios
  • How scary is Claude Mythos? 303 pages in 21 minutes

    How scary is Claude Mythos? 303 pages in 21 minutes
    Apr 10 2026

    With Claude Mythos we have an AI that knows when it's being tested, can obscure its reasoning when it wants, and is better at breaking into (and out of) computers than any human alive. Rob Wiblin works through its 244-page System Card and 59-page Alignment Risk Update to explain why:

    • Mythos is a nightmare for computer security
    • It has arrived far ahead of schedule
    • It might be great news for alignment and safety
    • But 3 key problems mean we can’t take its alignment results at face value
    • Mythos isn’t building its replacement yet, probably
    • Anthropic staff are, for the first time, kinda scared of Claude
    • He's losing sleep

    Learn more & full transcript: https://80k.info/mythos

    This episode was recorded on April 9, 2026.

    Chapters:

    • Why people are panicking about computer security (01:05)
    • Mythos could break out of containment (04:23)
    • Anthropic is losing billions in revenue by not releasing Mythos (06:21)
    • Mythos is actually the most aligned model to date, except… (07:48)
    • Mythos knows when it’s being tested (09:52)
    • Mythos can hide its thoughts (11:50)
    • Mythos can’t be trusted about whether it’s untrustworthy (14:02)
    • Does Mythos advance automated AI R&D? (17:03)
    • Mythos scares Anthropic (19:15)

    Video and audio editing: Dominic Armstrong, Milo McGuire, Luke Monsour, and Simon Monsour

    Camera operator: Dominic Armstrong

    Production: Elizabeth Cox, Nick Stockton, and Katy Moore
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    21 m
  • Village gossip, pesticide bans, and gene drives: 17 experts on the future of global health

    Village gossip, pesticide bans, and gene drives: 17 experts on the future of global health
    Apr 7 2026
    What does it really take to lift millions out of poverty and prevent needless deaths?In this special compilation episode, 17 past guests — including economists, nonprofit founders, and policy advisors — share their most powerful and actionable insights from the front lines of global health and development. You’ll hear about the critical need to boost agricultural productivity in sub-Saharan Africa, the staggering impact of lead poisoning on children in low-income countries, and the social forces that contribute to high neonatal mortality rates in India.What’s so striking is how some of the most effective interventions sound almost too simple to work: banning certain pesticides, replacing thatch roofs, or identifying village “influencers” to spread health information.Full transcript and links to learn more: https://80k.info/ghdChapters:Cold open (00:00:00)Luisa’s intro (00:00:58)Development consultant Karen Levy on why pushing for “sustainable” programmes isn’t as good as it sounds (00:02:15)Economist Dean Spears on the social forces and gender inequality that contribute to neonatal mortality in Uttar Pradesh (00:06:55)Charity founder Sarah Eustis-Guthrie on what we can learn from the massive failure of PlayPumps (00:14:33)Economist Rachel Glennerster on how randomised controlled trials are just one way to better understand tricky development problems (00:19:05)Data scientist Hannah Ritchie on why improving agricultural productivity in sub-Saharan Africa is critical to solving global poverty (00:24:36)Charity founder Lucia Coulter on the huge, neglected upsides of reducing lead exposure (00:47:48)Malaria expert James Tibenderana on using gene drives to wipe out the species of mosquitoes that cause malaria (00:53:11)Charity founder Varsha Venugopal on using village gossip to get kids their critical immunisations (01:04:14)Rachel Glennerster on solving tough global problems by creating the right incentives for innovation (01:11:31)Karen Levy on when governments should pay for programmes instead of NGOs (01:26:51)Open Philanthropy lead Alexander Berger on declining returns in global health, and finding and funding the most cost-effective interventions (01:29:40)GiveWell researcher James Snowden on making funding decisions with tricky moral weights (01:34:44)Lucia Coulter on “hits-based giving” approaches to funding global health and development projects (01:43:01)Rachel Glennerster on whether it’s better to fix problems in education with small-scale interventions versus systemic reforms (01:48:12)GiveDirectly cofounder Paul Niehaus on why it’s so important to give aid recipients a choice in how they spend their money (01:51:09)Sarah Eustis-Guthrie on whether more charities should scale back or shut down, and aligning incentives with beneficiaries (01:56:12)James Tibenderana on why we need loads better data to harness the power of AI to eradicate malaria (02:11:22)Lucia Coulter on rapidly scaling a light-touch intervention to more countries (02:20:14)Karen Levy on why pre-policy plans are so great at aligning perspectives (02:32:47)Rachel Glennerster on the value we get from doing the right RCTs well (02:40:04)Economist Mushtaq Khan on really drilling down into why “context matters” for development work (02:50:13)GiveWell cofounder Elie Hassenfeld on contrasting GiveWell’s approach with the subjective wellbeing approach of Happier Lives Institute (02:57:24)James Tibenderana on whether people actually use antimalarial bed nets for fishing — and why that’s the wrong thing to focus on (03:05:30)Karen Levy on working with governments to get big results (03:10:53)Leah Utyasheva on how a simple intervention reduced suicide in Sri Lanka by 70% (03:17:38)Karen Levy on working with academics to get the best results on the ground (03:29:03)James Tibenderana on the value of working with local researchers (03:32:15)Lucia Coulter on getting buy-in from both industry and government (03:35:05)Alexander Berger on reasons neartermist work makes sense even by longtermist standards (03:39:26)Economist Shruti Rajagopalan on the key skills to succeed in public policy careers, and seeing economics in everything (03:47:42)J-PAL lead Claire Walsh on her career advice for young people who want to get involved in global health and development (03:55:20)Audio engineering: Ben Cordell, Milo McGuire, Simon Monsour, and Dominic ArmstrongContent editing: Katy Moore and Milo McGuireMusic: CORBITCoordination, transcriptions, and web: Katy Moore
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    4 h y 7 m
  • What everyone is missing about Anthropic vs the Pentagon. And: The Meta leaks are worse than you think.

    What everyone is missing about Anthropic vs the Pentagon. And: The Meta leaks are worse than you think.
    Apr 3 2026

    When the Pentagon tried to strong-arm Anthropic into dropping its ban on AI-only kill decisions and mass domestic surveillance, the company refused. Its critics went on the attack: Anthropic and its supporters are some combination of 'hypocritical', 'naive', and 'anti-democratic'. Rob Wiblin dissects each claim finding that all three are mediocre arguments dressed up as hard truths. (Though the 'naive' one is at least interesting.)

    Watch on YouTube: What Everyone is Missing about Anthropic vs The Pentagon

    Plus, from 13:43: Leaked documents from Meta revealed that 10% of the company's total revenue — around $16 billion a year — came from ads for scams and goods Meta had itself banned. These likely enabled the theft of around $50 billion dollars a year from Americans alone. But when an internal anti-fraud team developed a screening method that halved the rate of scams coming from China... well, it wasn't well received.

    Watch on YouTube: The Meta Leaks Are Worse Than You Think

    Chapters:

    • Introduction (00:00:00)
    • What Everyone is Missing about Anthropic vs The Pentagon (00:00:26)
    • Charge 1: Hypocrisy (00:01:21)
    • Charge 2: Naivety (00:04:55)
    • Charge 3: Undemocratic (00:09:38)
    • You don't have to debate on their terms (00:12:32)
    • The Meta Leaks Are Worse Than You Think (00:13:43)
    • Three fixes for social media's scam problem (00:16:48)
    • We should regulate AI companies as strictly as banks (00:18:46)

    Video and audio editing: Dominic Armstrong and Simon Monsour
    Transcripts and web: Elizabeth Cox and Katy Moore
    Más Menos
    21 m
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For anyone who's interested in audiobooks, especially non-fiction work, this podcast is perfect. For people used to short-form podcasts, the 2-5 hour range may seem intimidating, but for those used to the length of audiobooks it's great. The length allows the interviewer to ask genuinely interesting questions, with a bit of back-and-forth with the interviewee.

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