With former 49ers coach Jim Harbaugh and the Los Angeles Chargers visiting Levi's Stadium for Saturday's preseason finale, San Francisco's final roster decisions are becoming more clear. Matt Maiocco and Jennifer Lee Chan discuss what will play into the 49ers' roster choices, including injury updates, player suspensions and position-group competitions. Also, Matt and Jennifer review how the entire 2025 NFL Draft class has fared throughout training camp, and discuss Kyle Shanahan's update on veteran wide receiver Demarcus Robinson's suspension following his violation of the NFL's personal conduct policy last season.

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(1:00) Demarcus Robinson suspension update
(2:00) Roster decisions shaping amid numerous injuries
(10:00) Health top priority as backups set to play in preseason finale
(20:00) Jim Harbaugh returns to Levi's Stadium as known program-fixer
(25:00) 49ers rookie progress

The 49ers won their second preseason game in dramatic fashion over the Las Vegas Raiders on Saturday at Allegiant Stadium after kicker Jake Moody converted a career-long 59-yard field goal to seal San Francisco's 22-19 comeback victory. Matt Maiocco and Jennifer Lee Chan break down the 49ers' nail-biting performance and how they've grown since their Week 1 preseason loss to the Denver Broncos, including quarterback Brock Purdy and receiver Ricky Pearsall's burgeoning connection. Matt and Jennifer analyze this crucial relationship on offense, update on San Francisco's injuries and highlight other top 49ers performers from the win.

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(1:00) Breaking down Week 2 preseason win vs. Raiders
(3:00) Jake Moody's confidence shows tangible gains from win
(5:00) Injury updates on Dominick Puni, other key players
(15:00) Analyzing the Purdy-Pearsall connection
(25:00) Picking star of the game for 49ers' defense

The 49ers began their second joint practice of the NFL preseason in Las Vegas much like their first week, undermanned. Undeterred, they fielded enough players against the Raiders to see some progress from last week. "49ers Talk" hosts Matt Maiocco and Jennifer Lee Chan break down which players were making the biggest impact in the second week of preseason and discuss two emerging rookies on both sides of the ball already making a case for regular-season minutes. Also, Matt and Jennifer update San Francisco's expansive injury room and share Kyle Shanahan's strategy for getting his starters some live reps throughout the rest of the preseason.

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(1:00) 49ers in Las Vegas for Week 2 of preseason
(3:00) CMC seems back to his normal self; coaches and players vouch
(6:00) 49ers' expansive injury updates
(11:25) Two rookies on both sides of the ball making cases for regular-season playing time
(38:00) How Kyle Shanahan will play veterans for rest of preseason