
The Code Breaker
Jennifer Doudna, Gene Editing, and the Future of the Human Race
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Narrado por:
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Kathe Mazur
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Walter Isaacson
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De:
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Walter Isaacson
Acerca de esta escucha
A 2022 Audie Award Finalist
A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post
The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.
When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.
Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.
The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.
Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids?
After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an “enthralling detective story” (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species.
©2021 Walter Isaacson. All rights reserved. (P)2021 Simon & Schuster, Inc. All rights reserved.Los oyentes también disfrutaron...
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- De: Walter Isaacson
- Narrado por: Nelson Runger
- Duración: 24 h y 40 m
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Benjamin Franklin is the founding father who winks at us - an ambitious urban entrepreneur who rose up the social ladder, from leather-aproned shopkeeper to dining with kings. In best-selling author Walter Isaacson's vivid and witty full-scale biography, we discover why Franklin turns to us from history's stage with eyes that twinkle from behind his new-fangled spectacles. In Benjamin Franklin, Isaacson shows how Franklin defines both his own time and ours. The most interesting thing that Franklin invented, and continually reinvented, was himself.
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Good book, not crazy about the narrator
- De Cathi en 07-20-13
De: Walter Isaacson
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- De: Jennifer A. Doudna, Samuel H. Sternberg
- Narrado por: Erin Bennett
- Duración: 9 h y 22 m
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Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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In to the abyss we ascend, a scary future
- De Philomath en 06-17-17
De: Jennifer A. Doudna, y otros
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Steve Jobs
- De: Walter Isaacson
- Narrado por: Dylan Baker
- Duración: 25 h y 18 m
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Based on more than 40 interviews with Jobs conducted over two years—as well as interviews with more than a hundred family members, friends, adversaries, competitors, and colleagues—Walter Isaacson has written a riveting story of the roller-coaster life and searingly intense personality of a creative entrepreneur whose passion for perfection and ferocious drive revolutionized six industries: personal computers, animated movies, music, phones, tablet computing, and digital publishing.
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Good Biography, Fine narrator
- De Chris en 10-27-11
De: Walter Isaacson
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Elon Musk
- De: Walter Isaacson
- Narrado por: Jeremy Bobb, Walter Isaacson
- Duración: 20 h y 39 m
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When Elon Musk was a kid in South Africa, he was regularly beaten by bullies. One day a group pushed him down some concrete steps and kicked him until his face was a swollen ball of flesh. He was in the hospital for a week. But the physical scars were minor compared to the emotional ones inflicted by his father, an engineer, rogue, and charismatic fantasist.
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megalomania on display
- De JP en 09-12-23
De: Walter Isaacson
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Profiles in Leadership
- Historians on the Elusive Quality of Greatness
- De: Sean Wilentz, Alan Brinkley, Annette Gordon-Reed, y otros
- Narrado por: Nicholas Hormann
- Duración: 11 h y 54 m
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What made FDR a more successful leader during the Depression crisis than Hoover? Why was Eisenhower more effective as supreme commander during World War II than he was as president? Why was Grant one of the best presidents of his day, if not in all of American history? What drove Bobby Kennedy into the scrum of electoral politics? Find the surprising and revelatory answers to these questions and more in this collection of new essays by great historians.
De: Sean Wilentz, y otros
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The Code Breaker—Young Readers Edition
- Jennifer Doudna and the Race to Understand Our Genetic Code
- De: Walter Isaacson
- Narrado por: Kathe Mazur
- Duración: 7 h y 38 m
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When Jennifer Doudna was a sixth grader in Hilo, Hawaii, she came home from school one afternoon and found a book on her bed. It was The Double Helix, James Watson’s account of how he and Francis Crick had discovered the structure of DNA, the spiral-staircase molecule that carries the genetic instruction code for all forms of life. This book guided Jennifer Doudna to focus her studies not on DNA, but on what seemed to take a backseat in biochemistry: figuring out the structure of RNA, a closely related molecule that enables the genetic instructions coded in DNA to express themselves.
De: Walter Isaacson
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Invent and Wander
- The Collected Writings of Jeff Bezos, with an Introduction by Walter Isaacson
- De: Jeff Bezos, Walter Isaacson - introduction
- Narrado por: L. J. Ganser
- Duración: 8 h y 55 m
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In this collection of Jeff Bezos' writings - his unique and strikingly original annual shareholder letters, plus numerous speeches and interviews that provide insight into his background, his work, and the evolution of his ideas - you'll gain an insider's view of the why and how of his success. Spanning a range of topics across business and public policy, from innovation and customer obsession to climate change and outer space, this book provides a rare glimpse into how Bezos thinks about the world and where the future might take us.
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Do the right thing.
- De FULL Creative en 12-06-20
De: Jeff Bezos, y otros
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Editing Humanity
- The CRISPR Revolution and the New Era of Genome Editing
- De: Kevin Davies
- Narrado por: Kevin Davies
- Duración: 16 h y 17 m
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Engrossing and captivating, Editing Humanity takes listeners inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces listeners to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale.
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Excellent content, solid execution
- De Samuel Finlayson en 01-25-21
De: Kevin Davies
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Einstein
- His Life and Universe
- De: Walter Isaacson
- Narrado por: Edward Herrmann
- Duración: 7 h y 18 m
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Based on the newly released personal letters of Albert Einstein, Walter Isaacson explores how an imaginative, impertinent patent clerk, a struggling father in a difficult marriage who couldn't get a teaching job or a doctorate, became the mind reader of the creator of the cosmos, the locksmith of the mysteries of the atom and the universe. His success came from questioning conventional wisdom and marveling at mysteries that struck others as mundane.
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This is the abridged version!
- De Benjamin en 04-27-07
De: Walter Isaacson
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The Double Helix
- A Personal Account of the Discovery of the Structure of DNA
- De: James D. Watson
- Narrado por: Grover Gardner, Roger Clark
- Duración: 4 h y 8 m
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By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.
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Star for Watson, Crick, Wilkins, AND for FRANKLIN
- De Darwin8u en 04-26-14
De: James D. Watson
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Cryptography
- The Key to Digital Security, How It Works, and Why It Matters
- De: Keith Martin
- Narrado por: Matthew Waterson
- Duración: 7 h y 45 m
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Despite its reputation as a language only of spies and hackers, cryptography plays a critical role in our everyday lives. Though often invisible, it underpins the security of our mobile phone calls, credit card payments, web searches, internet messaging, and cryptocurrencies - in short, everything we do online.
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Greatly enjoyed and learned
- De Glenn Nunes en 03-30-21
De: Keith Martin
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The Catalyst
- RNA and the Quest to Unlock Life's Deepest Secrets
- De: Thomas R. Cech
- Narrado por: Joshua Saxon
- Duración: 6 h y 54 m
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A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.
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Captivating
- De Auinash Kalsotra en 09-16-24
De: Thomas R. Cech
Lo que los oyentes dicen sobre The Code Breaker
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- Amazon Customer
- 01-13-22
Wonderful listen
Worth every minute it takes to digest this entire novel. Hard working folks who have such incredible imagination will move mankind’s health forward at incredible leaps and bounds. But even these scientists can’t save the lives of the anti-vaxers. Go science
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- Rick B
- 04-25-21
The Absolute Best!
This is a fantastic voyage beyond imagination that is highly relevant to our current COVID -19 pandemic. The story starts off narrated by the author, Walter Isaacson and closes with his excellent out look of the future of this technology. The majority of the audio book is read by Kathe Mazur who creates for the listener an enthusiastic venture by involving you deeply into the lives of all the scientists and researchers. This is a book for today and everything we are experiencing as it relates to microbiology and gene editing. The passion and competition for the solutions to our genetic understanding and ultimate use of the CRISPR tools will someday create a new world. I can not stress the importance of this excellent and dynamic story. Walter Isaacson is a master at taking a very advanced technology and breaking it down for easy understanding. Jennifer Doudna and Emmanuelle Charpentier, two very different personalities won the 2020 Nobel Prize in Chemistry. This is the first time in history that two women achieved this prestigious award for the same Science of Chemistry. The story starts off with a little girl, Jennifer who's father gives her a copy of the famous book "The Double Helix" by James Watson and Francis Crick as she learns of the most important detective story in history. Jennifer also finds out about Rosalind Franklin, who also could have won a Noble prize if the timing to her discovery was recognized correctly. Today we face the fact that through genetic modifications our science has the ability to modify our genes even down to the Germ line, which is where babies are created. We can fix broken genes to cure diseases like Huntington's or Sickle-cell anemia and many more by inserting corrections or by removing broken genes and completely change the direction of society if we so choose. Science as in all things can be used for positive or negative solutions. Let us hope through sharing important lessons such as in this book it will shape the future in the positive direction for the absolute best!
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- Archana
- 12-11-21
Much more than a book on Jennifer Doudna
Jennifer Doudna has certain contributed significantly, however, given Walter Isaacson prior books I thought it was too early to write a book on Jennifer. I picked up anyways as I am fan of all his prior booked. The book turned out to be much more than a biography of Jennifer. in fact the central character of the book really is the code of life - Gene or you can even say virus and bacterial which inspired the pioneering work on Crispr and Gene Editing. My favorite sections of the booked were though experiments on bioethics and how scientists put their differences aside to compare the Coronavirus pandemic. Section on Bioethics explore the slippery slope of allowing humanity to change their own genes, from treating diseases to producing designer babies. The section on Coronavirus elaborated how the time of crisis brings the entire world together to solve a problem that affects all. the innovation and collaboration spawned by COVID taught us how the basic sciences can find practical applications in matter of months and not years. Will be spending next week's and months quenching my curiosity on CRISPR, Gene Editing, and thorny topic of Bioethics.
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- Kathleen Johnsen
- 09-07-21
fascinating!
New thinking. Way over my knowledge, but repetitive enough on key pts to be instructional.
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- NRG
- 05-13-21
Powerful Priceless PrecisionX
Thank You For Priceless Education Information
Very Pleasant Listen
Rearranging Our Landscape
Mind Opening Excitement When You Know You Know
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- Amazon Customer
- 03-26-21
The future is here, the beginning of the beginning
The future is here, the beginning of the beginning has arrived. Our world will change a LOT in the next 20 years. A terrific and important read.
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- Scott Holman
- 11-26-21
Great and very informing read
I’ve read this book twice and sent copies to friend, they mostly loved it too
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- Maureen
- 04-20-21
Narration can be improved
The narration was confusing. Issacson did it. He was great. I think it could have been improved if there were a female narrator when Doudna was presenting her story. Sometimes I did not know if it was Issacson's point of view or hers.
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- Anonymous User
- 04-23-21
kindness succeeds even in the competitive world of
would have preferred it being read by Walter Isaacson. it was confusing who was speaking was a Jennifer doudna with a woman's voice or Walter Isaacson.
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- Hunter D. Black
- 07-01-21
Interesting read
This book is a bit technical, but very interesting and timely. It’s good to know there are so many super smart people working together, unlike our politicians.
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