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The Tangled Tree
- A Radical New History of Life
- Narrated by: Jacques Roy
- Length: 13 hrs and 48 mins
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Publisher's summary
Nonpareil science writer David Quammen explains how recent discoveries in molecular biology can change our understanding of evolution and life’s history, with powerful implications for human health and even our own human nature.
In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field - the study of life’s diversity and relatedness at the molecular level - is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection - a type of HGT.
In The Tangled Tree David Quammen, “one of that rare breed of science journalists who blends exploration with a talent for synthesis and storytelling” (Nature), chronicles these discoveries through the lives of the researchers who made them - such as Carl Woese, the most important little-known biologist of the 20th century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.
“Quammen is no ordinary writer. He is simply astonishing, one of that rare class of writer gifted with verve, ingenuity, humor, guts, and great heart” (Elle). Now, in The Tangled Tree, he explains how molecular studies of evolution have brought startling recognitions about the tangled tree of life - including where we humans fit upon it. Thanks to new technologies such as CRISPR, we now have the ability to alter even our genetic composition - through sideways insertions, as nature has long been doing. The Tangled Tree is a brilliant guide to our transformed understanding of evolution, of life’s history, and of our own human nature.
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- Unabridged
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The atom, the big bang, DNA, natural selection - all are ideas that have revolutionized science; and all were dismissed out of hand when they first appeared. The surprises haven't stopped in recent years, and in At the Edge of Uncertainty, best-selling author Michael Brooks investigates the new wave of radical insights that are shaping the future of scientific discovery.
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All smoke, no fire
- By Kenton on 07-25-15
By: Michael Brooks
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Herding Hemingway's Cats
- Understanding How Our Genes Work
- By: Kat Arney
- Narrated by: Kat Arney
- Length: 8 hrs and 39 mins
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The language of genes has become common parlance. We know they make your eyes blue, your hair curly or your nose straight. The media tells us that our genes control the risk of cancer, heart disease, alcoholism or Alzheimer's. The cost of DNA sequencing has plummeted from billions of pounds to a few hundred, and gene-based advances in medicine hold huge promise. So we've all heard of genes, but how do they actually work?
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A non-scientists misguided interpretation
- By AraSevera on 05-15-16
By: Kat Arney
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The Cosmic Serpent
- DNA and the Origins of Knowledge
- By: Jeremy Narby
- Narrated by: James Patrick Cronin
- Length: 4 hrs and 55 mins
- Unabridged
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This adventure in science and imagination, which the Medical Tribune said might herald "a Copernican revolution for the life sciences", leads the listener through unexplored jungles and uncharted aspects of mind to the heart of knowledge. In a first-person narrative of scientific discovery that opens new perspectives on biology, anthropology, and the limits of rationalism, The Cosmic Serpent reveals how startlingly different the world around us appears when we open our minds to it.
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Very Good Religious Text
- By Blair K. Hartman on 08-09-17
By: Jeremy Narby
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Time, Love, Memory
- A Great Biologist and His Quest for the Origins of Behavior
- By: Jonathan Weiner
- Narrated by: Kevin Pariseau
- Length: 11 hrs and 37 mins
- Unabridged
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Jonathan Weiner, winner of the Pulitzer Prize for The Beak of the Finch, brings his brilliant reporting skills to the story of Seymour Benzer, the Brooklyn-born maverick scientist whose study of genetics and experiments with fruit fly genes has helped revolutionize or knowledge of the connections between DNA and behavior both animal and human.
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This is a profound science book
- By Timothy A. Smith on 05-12-10
By: Jonathan Weiner
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A Crack in Creation
- Gene Editing and the Unthinkable Power to Control Evolution
- By: Jennifer A. Doudna, Samuel H. Sternberg
- Narrated by: Erin Bennett
- Length: 9 hrs and 22 mins
- Unabridged
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Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.
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In to the abyss we ascend, a scary future
- By Philomath on 06-17-17
By: Jennifer A. Doudna, and others
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13 Things That Don't Make Sense
- The Most Baffling Scientific Mysteries of Our Time
- By: Michael Brooks
- Narrated by: James Adams
- Length: 8 hrs and 58 mins
- Unabridged
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Science starts to get interesting when things don't make sense. Science's best-kept secret is that there are experimental results and reliable data that the most brilliant scientists can neither explain nor dismiss. If history is any precedent, we should look to today's inexplicable results to forecast the future of science. Michael Brooks heads to the scientific frontier to meet 13 modern-day anomalies and discover tomorrow's breakthroughs.
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10 interesting chapters-read epiloge first
- By Stephen on 06-10-09
By: Michael Brooks
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Headstrong
- 52 Women Who Changed Science-and the World
- By: Rachel Swaby
- Narrated by: Lauren Fortgang
- Length: 7 hrs and 1 min
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In 2013, the New York Times published an obituary for Yvonne Brill. It began: “She made a mean beef stroganoff, followed her husband from job to job, and took eight years off from work to raise three children.” It wasn’t until the second paragraph that readers discovered why the Times had devoted several hundred words to her life: Brill was a brilliant rocket scientist who invented a propulsion system to keep communications satellites in orbit, and had recently been awarded the National Medal of Technology and Innovation.
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Role models for young women
- By mtsuda90 on 06-25-16
By: Rachel Swaby
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The Upright Thinkers
- The Human Journey From Living in Trees to Understanding the Cosmos
- By: Leonard Mlodinow
- Narrated by: Leonard Mlodinow
- Length: 12 hrs and 29 mins
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In this fascinating and illuminating work, Leonard Mlodinow guides us through the critical eras and events in the development of science, all of which, he demonstrates, were propelled forward by humankind's collective struggle to know. From the birth of reasoning and culture to the formation of the studies of physics, chemistry, biology, and modern-day quantum physics, we come to see that much of our progress can be attributed to simple questions - why? how? - bravely asked.
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10/10 Got What I Wanted.
- By Austin on 09-22-15
By: Leonard Mlodinow
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Evolution
- The Remarkable History of a Scientific Theory
- By: Edward J. Larson
- Narrated by: John McDonough
- Length: 9 hrs and 41 mins
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Edward J. Larson is a Pulitzer Prize-winning author and eminent science historian. This marvelously readable, yet sumptuously erudite work traces the development of the scientific theory of evolution. From Darwin's essential trip to the Galápagos, to the most contemporary studies in sociobiology, this work takes listeners both into the field and laboratories of the world's greatest evolutionary scientists, and shows how the theory of evolution has itself evolved.
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An Excellent History!
- By Bradly D. Elder on 08-13-07
By: Edward J. Larson
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The Lives of a Cell
- Notes of a Biology Watcher
- By: Lewis Thomas
- Narrated by: Grover Gardner
- Length: 4 hrs and 12 mins
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In The Lives of a Cell, Dr. Lewis Thomas opens up to the listener a universe of knowledge and perception that is perhaps not wholly unfamiliar to the research scientist; but the world he explores is also one of men and women, of complex interrelationships, old ironies, peculiar powers, and intricate languages that give identity to the alienated and direction to the dependent. This remarkable work offers a subtle, bold vision of humankind and the world around us - a sense of what gives life - from a writer who seems to draw grace and strength from the very substance of his subject.
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So enlightening and enjoyable!
- By Flora on 03-15-18
By: Lewis Thomas
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Brief Candle in the Dark
- My Life in Science
- By: Richard Dawkins
- Narrated by: Richard Dawkins
- Length: 13 hrs and 53 mins
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In this hugely entertaining sequel to the New York Times best-selling memoir An Appetite for Wonder, Richard Dawkins delves deeply into his intellectual life spent kick-starting new conversations about science, culture, and religion and writing yet another of the most audacious and widely read books of the 20th century - The God Delusion.
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I'm a Dawkins Groupie but...
- By Anne on 10-18-15
By: Richard Dawkins
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The Seven Daughters of Eve
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In 1994 Professor Bryan Sykes, a leading world authority on DNA and human evolution, was called in to examine the frozen remains of a man trapped in glacial ice in northern Italy. News of both the Ice Man's discovery and his age, which was put at over 5,000 years, fascinated scientists and newspapers throughout the world. But what made Sykes's story particularly revelatory was his successful identification of a genetic descendant of the Ice Man, a woman living in Great Britain today. How was Sykes able to locate a living relative?
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Eurocentric
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What listeners say about The Tangled Tree
Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Dennis
- 08-18-18
Very Enjoyable and Readable
This book provides an extremely interesting, enjoyable, and readable overview of the history of the theory of evolution, from Darwin and before, up to the most current ideas. The central figure in the book is Carl Woese, who discovered Archaea, and there are also many engaging mini-biographies of other important figures (Charles Darwin, of course, but also Ernst Haeckel, Lynn Margulis, Ford Doolittle, and several others), and explanations of their contributions to the science.
The author explains a lot about biology, and cellular biology in particular, in support of the author’s central thesis; that different forms of life are far more interrelated that we realized just a few decades ago (hence the name of the book). This greater degree of interrelation arises because of Horizontal Gene Transfer (“HGT”), by which means living organisms can transfer their genes to organisms in other species or even other kingdoms or domains. The transplanted genes might not have any impact on the new host, or they might be harmful, or they might be beneficial. An example of the latter category is the gene that enables mammals to develop placentas.
The author also explains a great deal about cellular biology, with clear explanations of how scientists painstakingly figured out how cells work, from the first observations of bacteria in the 1600s, to the functions of ribosomes and DNA, to Carl Woese’s discovery of archaea, and, ultimately, to the importance of Horizontal Gene Transfer in both evolution and medicine.
In addition to the science, the book goes into conflicts between scientists with different points of view, or scientists who agree on the science but disagree about who should get credit, and the importance of getting credit for grant applications and tenure awards. As an outsider, I found this insight into the human side of the scientific community fascinating.
I come at the subject of evolution from the Intelligent Design point of view (though I am a Christian, I don’t believe that science supports a literal interpretation of the book of Genesis). One of the things I found refreshing about this book is that it didn’t contain attacks on people like me who believe that evolution could only make sense if it was intelligently guided.
I won’t lie about the science; at times, it got pretty dense. But the author does a good job of explaining the science in an understandable way, and I was able to get the important concepts, though I have no science background.
I purchased and listened to the audiobook. The narrator did a fantastic job – his pacing and enunciation were terrific, and his voice was very pleasant.
This book is highly recommended.
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- 11-15-18
Not as good as I had hoped
I feel so disappointed. It was like being a kid and getting a half eaten chocolate Santa on Christmas as your only gift. This seems like a book half written. When I got the the end, I just sat there in completely disbelief. Some parts of this book are exceptional. For example, this is an incredibly detailed and informative history of how scientists and the public came to understand the tree of life, how our understanding changed to see it as a web, and finally, merely a starting point with no shape. In many ways, biology mimics physics in this regard. Newton gave us the laws of the universe that work very well on the larger scale, but when you dig deeper, it is clear that the very small has quantum rules all its own. A similar thing is going on with the tree of life. The tree Darwin played around with works very well for later evolved species. We can, with great success, trace our ancestry back to earlier branches. However, when we get to the earliest species on the tree, archaea and bacteria, there was so much horizontal gene transfer (bacteria and archaea swapping genes instead of handing them down through generation) that we cannot trace a universal common ancestor. This story needed to be told. The only problem is, this story really wasn't told completely! And what a shame. Parts of this story never made it onto the page. This seems to be because Quammen wanted to focus on a biography of Carl Woese. Woese was a pioneer who discovered archaea and fought for their place on the tangled tree. He went to war with giants like Lynn Margulis, George Fox, and so many others. All of that was essential to include. However, there was a shocking turn of events when Quammen wrote about visiting Bill Martin (who he refers to as William F. Martin, and not Bill, which seemed odd to begin with). It was almost as if Quammen didn't really understand the work Martin has devoted his life to. Quammen talked about endosymbiosis being a single event; so he understood that part of Martin's research. He even discussed hydrothermal vents, but not in relation to Martin's work and discussed it so very briefly and it was clear he wasn't making the connections he was supposed to. He wrote about Martin and then *immediately* discussed that Woese guess that the RNA world is the correct hypothesis of how the first cells came to assemble. Did this just not come up when he spoke with Martin? I find that almost impossible to fathom. I find Qaummen not having read Martin, Russell, or Lane's work on the origin of life almost an impossibility. But yet, it seems he really wasn't familiar with it. Quammen went so far as to say he thought Woese was probably right about the RNA world. He then said that other people disagree but didn't say *how* they disagree. He never talked about Martin, Russell, and Lane's work (among others) who accounted for the energy needed for the cells to assemble. He never quite showed an understanding of how the hydrothermal vent hypothesis (or other processes that focus on the laws of thermodynamics and can show how free energy was available for the assembly of RNA, DNA, amino acids, fats, etc) challenge the RNA world hypothesis (and for damn good reason). I kept thinking, "Oh he must be saving Martin's objections to the RNA world for later in the book." Later never came.
There is too much missing in this extremely important story to rate this book well. How we view the tree is extremely important. So, I appreciate how much detail was included. There are incredible sections about the work of Margulis. She really got her due in this book. Quammen wrote about the things she got right and what she got wrong, but he had equal respect for her and her male peers. I don't find this is always the case and was extremely happy to see how he managed her story. His sections of horizontal gene transfer were some of the most important sections included in this book (but probably could have been done better). His depiction of the many fights people had over the tree (is it a web, 5 kingdoms, 3 domains), and if we should even call archaea bacteria (no, we should not) were great. The sections on Darwin, and even Woese hatred for Darwin, were wonderful. Jumping genes and how they created a womb were all top notch, and things the public really needs to know. Quammen even included exciting little tidbits, such as how sponges can be both a multicellular organism and yet a single cell organisms if the environment dictates (but this really lacked the wow factor that other writers have managed to capture) or the tale of wolbachia, one of my very favorite bacteria, who control the sex of the new wolbachia produced (again, told in much more captivating manner by Ed Yong, who Quammen recommends reading, as do I).
But none of his spectacular writing made up for the loss of what was missing from this story. I appreciate that Quammen chose this topic at all. But, I was left feeling like I do when I read a NYT science article that picked up the ball and ran with it before it was ready. When I finished this book, I found myself wishing, so desperately, that Nick Lane had chosen to write about this subject. It would have been a much better (more complete) book.
#tagsgiving #sweepstakes
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- NJ
- 08-26-18
Should've had pdf with at least some illustrations
Love the story and the narrator. So much is related to visual presentation of ideas and book would have benefited from the pdf many titles have with at least some of the illustrations.
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- JohnS
- 08-23-18
Quammen at his usual best
The Tangled Tree is a wonderful mixture of human and non human characters. D. Quammen has done an excellent job at distilling the fascinating aspects of C. Woese's work his collaborators and detractors. Like his writing in The Song of the Dodo and The Flight of the Iguana, for example, his work is clear and should reach a wide audience of folks interested in science in general and biology in particular. Sure, some passages demand a little more effort by the reader/listener, but this is expected given the intricacies of the topic involved. The narration by Jacques Roy is right on, including the few passages where he added an accent to the person quoted. All in all a deserving 5-star.
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- Anne S Wagner
- 07-22-19
Partly Science, Partly Biography .
The science in this book was very challenging! I will remember the gist but not the detail. The stories about the individuals involved were really interesting. Because I love Quammen's writing so much, and because I wanted some understanding of the historic changes in our knowledge that were being discussed, I hung it in. And, I'm glad I did although sometimes it was a slog.
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- Rachel
- 09-08-18
kind of interesting topic, but not engaging book
The topic sounds interesting and it kind of was, but I had trouble keeping with it. I listened, but my mind would wander or I'd immediately forget what was being discussed. Somehow it wasn't as engaging as I'd hoped for.
The main story throughout the book is a history of the different ways folks thought about and represented the "tree" of live throughout it's history. That's actually just fine, but not really radical. I was hoping for a bit more "action" about how people didn't used to think that we had other forms of life inside our bodies and now we know we do. But besides gut microbes and their ilk, there wasn't much discussion of what that means. There was some discussion of viral DNA in placentas, but it could have been presented in a more engaging way, I felt.
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- ASakaeva
- 09-24-18
Another great book from David Quammen
As always, David Quammen delivers a very well researched and well written book on a complicated scientific subject. His works make tough scientific topics super approachable! Personally, I was a Molecular biology major, so all of the big words and concepts were familiar to me, but I really enjoyed the history aspect of the storyline and I think people of all backgrounds will find this book interesting.
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- Gary
- 09-06-18
Life's a funny riddle, solve it
There is no one correct way of dividing a world, identity is fleeting and reification leads to oversimplification. All of that is within this book as the author looks at where the incredibly interesting world of microbiology stands today and what it means for understanding our current understanding of the world we find ourselves in. I have read many stimulating books on the early 20th century development of quantum physics and gravitational theory and this book has that feel to it and lays out the recent and just as exciting history of why micro and molecular biology’s recent discoveries about whom we are and where we came from is just as exciting.
I have to expand on my first sentence above because it might not be obvious how this book embraces that sentence in such a succinct way. First, ‘no correct way of dividing the world’, Darwin’s greatest realization was that there is no absolute ‘nature of things’ in and of themselves (i.e. ‘a unique world structure’ or an unique ontological foundation), essences are human imposed order on to the world, and for his theory to work ‘species’ needed a fluid nuanced definition and its own inherent truth was a myth (‘essences’ and species are not things they are human constructs). Even though Darwin titles his book ‘On the Origin of Species’ he dances around the meaning of the word ‘species’ because without fluidity he can’t get to evolution by way of natural selection.
Second ‘identity is fleeting’, the individual under consideration might not always be as obvious as common sense dictates. The author gave the example by asking is it the ant, the colony or all of the colonies that make the entity worthy of consideration, and the author made note of the ship of Theseus and its paradox as related to self identity of the individual. In other words, if we were to analyze every single oyster would we understand the oyster? Or as Nietzsche once mockingly said by way of criticizing philosophy ‘would we be any nearer to the truth of understanding women by asking every woman what they want’. Or, moreover, are bacteria best thought of as individuals or can they be thought of in their totality as one? Descartes takes the world away from us with his cogito by literally assuming it away, but Kierkegaard, Nietzsche and Heidegger think we are not separate from the world and the world needs to be considered in order to understand our Being.
The third item from my opening sentence is on ‘reification’. Is the map actually the thing? Or in the case for this book is the ‘tree of life’ such as nature demands it, or do we as humans make nature fit our model, the tree of life. I love Darwin and I love his book and I love when people say that they accept ‘evolution by way of natural selection’ as the best description to explain how life developed over the eons, but in reality the truth is more nuanced and especially for the first 3 billion years of life on earth and even in our more recent history (check out what the author tells the reader about the placenta and what we think we know about it!).
The power plant that produces the universal currency of life by creating ATP (little battery like energy sources) by way of the cells mitochondria and are within all living creatures that have complexity with structure and that are more complicated than bacteria or archaea or fungi or blue-green algae and which are not plants (i.e. get their energy directly from the sun through chloroplast) for each and every eukaryote that has ever lived (humans are eukaryotes since we are made up of cells that usually have a nucleolus and organelles and mitochondria) or are alive today that original event of endobiosis happened only once in the history of the world (endobiosis is a big theme within this book and will be explained in great detail for the observant reader). The fact that event only happened once as stated in this book always floors me and anyone who thinks that the galaxy or the universe is teeming with complex intelligent life first needs to explain why that event only happened once on earth as far as we know today.
The chapters on Lynn Margulis were fascinating and illustrated why this book was so very fun to read. First, I had no idea she was Carl Sagan’s first wife. She latched on to a concept that was only on the fringes of microbiology and made it mainstream. Scientists in general hate nothing more than to have their paradigms be overturned while an individual scientist likes nothing more than to challenge the status quo and overthrow a paradigm. Science knows itself by correcting itself. Lynn Margulis took what was known within footnotes and mostly obscure corners (including, most probably, a Russian pedophile) and popularized HGT (horizontal gene transfer) and gave it a pedigree that was lacking. Margulis is a scientist worth knowing and remembering, and oddly, she couldn’t help herself in later days by goofingly thinking 9/11 was an inside job or thinking HIV did not cause Aids (fringe thinking also, but wrongheaded).
I had previously read Margulis’ book ‘The Five Kingdoms’, and therefore I have a bias towards how she sees the world and it explains why I think archaea are different from bacteria and prokaryote is the wrong label for them. I would recommend that book not to read but to look at the beautiful pictures of single cell life, and one day when you happen to be in a used book store do yourself a favor and pick it up at least to glance through.
Overall this book doesn’t make a definitive statement on how many life kingdoms there are and how the tree of life should be designed. That’s a feature not a bug with this book because in the end there aren’t absolutely correct ways of categorizing the world or if there are we don’t know it when we get it right. I don’t want to give away the punch line in this book, but the very last sentence of this book made me laugh out loud, and will make you laugh too.
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- Max
- 09-18-18
exceptional
exceptional. i am a researcher in the field and the science here is exceptional. much appreciation.
and i also loved the acting.
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- Klara June
- 09-13-18
One of the Best of 2018 Science Books
I thoroughly enjoyed this book and was sorry when I came to the end. The Tangled Tree explains the current thinking in evolutionary theory in terms that are understandable by anyone, even those without a background in biology. Horizontal gene transfer is the most exciting discovery in the field since Darwin. David Quammen has done an excellent job of describing the history of evolutionary theory to date as well as humanizing the scientists involved. Highly recommended!
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