What is consciousness, really? Why does it not simply switch on at a single moment? Neuroscientist Niko Kukushkin explains how even single cells can show primitive forms of memory and agency, why the human mind is not a mysterious force floating above biology, and why reducing it to “just neurons” misses what actually matters.

He also discusses the evolutionary gamble of complexity, why bacteria still dominate the planet, and how abstraction and memory together give rise to thought.

At the center of the conversation is an unsettling question: Why does it feel so special to be you when science says that you are nothing but a chemical reaction—a collection of atoms and molecules, like rocks, paperclips, and everything else in the physical universe?

Nikolay Kukushkin is a clinical associate professor at New York University and a research fellow at NYU’s Center for Neural Science, where he studies how temporal patterns shape memory formation. He holds degrees from St. Petersburg State University and Oxford University, and completed postdoctoral training at Harvard Medical School. He is the author of a recent paper in Nature Communications demonstrating canonical memory in non-neural cells. His book is One Hand Clapping.

Francis Crick is best known as one of the figures behind the discovery of the double-helix structure of DNA, but the familiar story leaves out as much as it explains. Historian of science Matthew Cobb looks closely at how Crick’s life actually unfolded, revealing a career shaped less by inevitability than by luck, conflict, false starts, and a series of highly contingent moments.

The double helix itself may have been waiting to be found, but what followed was anything but predetermined. Crick’s influence came from asking uncomfortable questions about what the structure of DNA implied for genetics, evolution, and life itself. Along the way, myths hardened around personalities, credit, and rivalries, especially in the case of Rosalind Franklin, whose role has been both misunderstood and oversimplified.

The conversation also traces Crick’s later turn away from molecular biology toward the problem that fascinated him from the beginning: consciousness. From visual perception to the search for neural correlates of experience, his ambition was to push back against mystical explanations and insist that even the most elusive aspects of the mind belonged to the material world.

Matthew Cobb is a professor in the School of Biological Sciences at the University of Manchester. He is the author of numerous works of science and history. His new book is Crick: A Mind in Motion, a biography of the legendary scientist Francis Crick, co-discoverer of the structure of DNA.

What do you do when someone believes you shouldn’t exist?

Daryl Davis didn’t protest. He didn’t shout. He sat down, asked questions, and kept showing up. Over decades, that approach has led more than 200 Ku Klux Klan members and white supremacists to walk away from their robes for good.

In this conversation, Davis explains why people radicalize, and what happens psychologically when prejudice collides with a real human being. He shares stories from inside Klan meetings, lessons learned from neo-Nazis, and why today’s climate of polarization may actually be an opportunity rather than a dead end.

Daryl Davis earned his Bachelor of Music degree from Howard University and an Honorary Doctorate in Humane Letters from Post University. He is the author of Klan-Destine Relationships and the subject of the multi-award-winning documentary Accidental Courtesy, which chronicles his work in race reconciliation. A lifelong musician, he has performed with Chuck Berry and President Bill Clinton, and as an actor appeared in HBO’s The Wire.