President Trump has signed an order to reclassify cannabis, moving it from Schedule I to Schedule III drug. Savage discusses the impact of high THC marijuana on adolescent brain development and public health with Laura Stack, founder of Johnny's Ambassadors. Laura shares her personal tragedy of losing her son, Johnny, to suicide after he developed cannabis-induced psychosis. The conversation addresses the normalization and legalization of marijuana, its connections to mental health issues, increased potency in modern cannabis products, and its negative effects on youth, including psychosis, violence, and addiction. They discuss how emergency rooms nationwide have been plagued by 'scromiting' a debilitating condition that triggers episodes of relentless nausea, abdominal pain and severe vomiting in chronic weed users. Learn how profits are being prioritized over the health of the people. They also touch on political influences and the need for more public education to combat the growing epidemic of marijuana-related harms among teenagers.

Savage addresses the troubling proliferation of hate and rage on social media and its role in driving engagement, while traditional media declines. He discusses the shocking violence, including the murder of Rob Reiner and his wife by their own son, a massacre of innocent Jews by two Muslims, and the unexplained killings at Brown University. He questions why such events are becoming more frequent. Savage explains how hate has become commercialized and speculates what role marijuana may play in the rise of violence and psychosis.