Following an alcohol-induced, relationship-combusting one-night stand, Isabelle Beckett finds herself suddenly single. Caught up in her big-city career with an art auction house, her life is an enviable whirl of glamorous gallery openings, avant-garde ironing boards, and once-in-a-lifetime discoveries. That is, until Isabelle faces the fact that being single in a strange city is an experience for which she is quite unprepared.
Forced to contend with hostile taxi drivers, fanged spiders in the shower, and the humiliation of being discovered by her latest crush in a wetsuit-tutu combo, she struggles to retain her dignity and belief in romantic destiny. And then, just when she seems to be regaining control of life, Isabelle finds herself on the hit list of a Serial Dater.