When Mike Watterson wakes to what he believes to be the best day of his life, his dreams are soon crushed as he is turned down for the job interview that could change his life. His world is turned upside down the next day as he wakes to a zombie apocalypse that he must survive.
When things look grim, Death himself saves Mike and brings his soul to the underworld. It is there that Mike finds out the apocalypse is affecting not only Earth but existence itself. He enlists Mike's aid to investigate the cause of the epidemic in the living world while he searches the afterlife with his fellow horsemen.