• Introduction & Welcome — 0:17
• Jack's Background in Healthcare AI — 0:58
• Brief History of AI — 3:57
• The "Perfect Storm" That Created Modern AI — 5:48
• From General to Specialized: Fine-Tuning AI for Medicine — 7:04
• LLM Confidence & the Sycophancy Problem — 13:01
• The Benchmark Problem — 14:25
• Building Your Own Personal AI Benchmark — 17:44
• Can You "Turn Off" AI Sycophancy? — 20:00
• RAG Systems & How Specialty AI Tools Work — 22:09
• Choosing the Right AI Tool for Clinical Use — 26:18
• Why 95% of AI Pilots Fail in Deployment— 28:10
• How to Ask AI Questions Well (Prompt Quality) — 31:25
• Knowledge Base Currency & Sam's Drug Withdrawal Test — 35:06
• Closing & Contact Info — 37:12

In this episode, Sam Ashoo, MD and Dr. Dana Klavansky, MD discuss the March 2026 Emergency Medicine Practice article, Emergency Department Evaluation and Management of Severe Traumatic Brain Injury

• Introduction & Welcome (0:15)
• Guest Introduction (0:55)
• Epidemiology of Severe TBI (2:37)
• Pathophysiology: Primary vs. Secondary TBI (4:24)
• Types of Hemorrhage and Hematomas (5:25)
• Classification (7:31)
• Mild vs. Moderate vs. Severe TBI
• Impact Loading vs. Inertial Loading
• Differential Diagnosis (9:22)
• Prehospital Care (9:42)
• Emergency Department History (13:33)
• Diagnostics (15:13)
• CT Scan and the A-B-B-B-C Approach
• Repeat CT Timing
• Bedside Ultrasound for Optic Nerve Sheath Diameter
• Pupillometry
• Biomarkers
• Treatment (24:52)
• Airway Management
• Ventilation and CO2 Targets
• Hyperosmolar Therapy: Hypertonic Saline and Mannitol
• Cerebral Perfusion Pressure
• Blood Pressure Goals
• Temperature Management
• Coagulopathy Management
• Seizure Prophylaxis and EEG Monitoring
• Tiered ICP Management (35:29)
• Surgical Indications (38:40)
• Prognosis (40:33)
• Special Topics (41:30)
• Sports Injuries and CTE
• Tranexamic Acid (CRASH-3 Trial)
• Wrap-Up (43:46)

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In this episode, Sam Ashoo, MD and T.R. Eckler, MD discuss the February 2026 Emergency Medicine Practice article, Emergency Department Diagnosis and Management of Acute Coronary Occlusion

00:00 - Introduction & Welcome

01:21 - Episode Overview: Acute Coronary Occlusion

02:06 - Why This Topic Matters: Statistics & New Guidelines

03:35 - Nomenclature: ACO vs STEMI/NSTEMI

06:15 - Differential Diagnosis for STEMI

07:41 - Pre-Hospital Care & EMS Role

11:37 - Patient History & Presenting Symptoms

12:28 - Physical Examination Findings

14:54 - EKG: The Most Important Test

17:00 - STEMI Definition & Criteria

20:32 - STEMI Equivalents: Scarbosa Criteria

22:40 - Smith Modified Scarbosa Criteria

24:10 - Hyperacute T Waves

25:30 - Posterior STEMI

28:40 - De Winter Sign

29:38 - Non-STEMI EKG Findings

31:30 - AVR ST Elevation

32:47 - Wellens Syndrome

33:54 - Reciprocal ST Segment Changes

36:15 - Inferior MI Patterns

37:54 - Laboratory Testing

39:51 - Imaging: Chest X-Ray & Echocardiography

42:25 - Supplemental Oxygen: What the Evidence Shows

44:50 - Analgesia & Pain Management

46:35 - Pharmacotherapy: Aspirin & Antiplatelet Agents

49:18 - Reperfusion Therapies & Thrombolytics

53:05 - Cardiac Arrest in STEMI Patients

53:55 - Closing Remarks & CME Information