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Publisher's Summary

Welcome to Forbes for January 3rd, 2011 from Audible. This edition contains seven feature articles.

The cover story is "Gene Machine" - Jonathan Rothberg's desktop decoder could kick off a revolution in medicine, food, energy, even consumer products--and ignite the next $100 billion technology market.

Also, "The Man Behind Oprah" - David Zaslav is a longtime TV exec, but his new Oprah Winfrey Network will define him--one way or another.

Next, "Under the Gun" - As Pentagon budgets shrink, Linda Hudson must transform defense giant BAE Systems. It will not be easy or cheap.

We'll also tell you about "Genome Hackers" - In an era of cheap gene scans and vast DNA databases, will consumers be able to keep their sensitive genetic information private?

Then, "Shrink It, Cure It" - GlaxoSmithKline Chief Andrew Witty has a plan to save the struggling drugmaker: Turn it into a collection of entrepreneurial biotech outfits.

Followed by "The Resurrection of Alan Schwartz" - Humbled by the collapse of Bear Stearns he has found a new life--and new challenges--in turning Guggenheim Partners into Wall Street's newest comer.

And in our final story "One Pharma Entrepreneur's Never Ending Quest" Lisa Conte mustered $200 million to make prescription drugs from plants. Payoff may be in sight.

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