The Human Upgrade: Biohacking for Longevity & Performance Podcast Por Dave Asprey arte de portada

The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

De: Dave Asprey
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For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.

Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.

This isn’t just self-improvement - it’s human enhancement backed by data.

Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.

Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

© Copyright © Bulletproof Media 2023 Ciencia Desarrollo Personal Higiene y Vida Saludable Éxito Personal
Episodios
  • Why Breathwork Feels Like a Euphoric Drug | Biohacker Tips : 1369

    Why Breathwork Feels Like a Euphoric Drug | Biohacker Tips : 1369
    Nov 25 2025
    Breathwork is one of the most powerful tools in biohacking, yet most people only experience the surface level techniques. When you use it the right way, breathwork can upgrade your brain, strengthen your nervous system, improve sleep, and open awareness states that amplify longevity and human performance. This episode features Ishan Shivanand, a globally celebrated yogic scholar, mental health researcher, and bestselling author who was raised in the monasteries of India under Mahasiddha Avdhoot Shivanand. He carries one of the world’s oldest Shiv Yogi lineages and created the clinically validated Yoga of Immortals method, which has helped millions reverse anxiety, depression, insomnia, burnout, and trauma. Together, Host Dave Asprey and Ishan reveal how lineage level breath practices shape consciousness, neuroplasticity, and emotional resilience. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey and Ishan explore the full arc of ancient yogic training, from how breathwork directs prana through the body to how chanting alters brain states, emotional regulation, and nervous system function. They break down the role of visualization in building neuroplasticity, the symbolism and physics of sacred sound, and the science of moving awareness through the spine. The conversation moves into rarely discussed topics including the yogic art of choosing one’s death, how advanced practitioners leave the body, the meaning of immortality in spiritual traditions, and how dharma shapes whether long life becomes a blessing or a burden. You will hear how ancient monks trained through martial arts, mantra repetition, sacred geometry, gold symbolism, alchemy, and the cultivation of higher states of consciousness, and how these practices compare to modern biohacking tools like fasting, ketosis, nootropics, supplements, sleep optimization, functional medicine, and mitochondrial support. This episode shows you how Eastern mystical training and Western performance science intersect and how these teachings fit naturally within the Smarter Not Harder framework. This conversation also covers plant medicine, psychedelics, and the difference between ancient ceremonial use and modern recreational misuse. You will hear how lineage based training uses breath, awareness, and mantra to alter redox balance, regulate the autonomic nervous system, strengthen energy production, and shape brain optimization at the deepest levels. You’ll Learn: • Why breathwork changes brain states faster than basic meditation and how it drives neuroplasticity • How chanting affects the vagus nerve, emotional regulation, and nervous system balance • How visualization strengthens nerve pathways, trauma resolution, and sleep optimization • The meaning behind sacred sound, vibration, and the origins of consciousness in ancient lineage training • Why monks train with martial arts, mantra repetition, and sacred geometry to enhance awareness • How yogic philosophy approaches immortality, choosing one’s death, and leaving the body consciously • Why dharma shapes whether long life becomes a blessing or a curse • How plant medicine differs when used ceremonially versus recreationally • How to integrate these teachings into your own longevity, performance, and human potential strategy Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: advanced breathwork techniques, prana movement training, mantra induced trance states, sacred sound vibration science, visualization neuroplasticity practice, yogic spinal awareness training, autonomic nervous system regulation, ancient Himalayan lineage meditation, art of conscious death practice, yogic immortality teachings, dharma based longevity strategy, astral body leaving techniques, yogic alchemy and transformation, sacred geometry meditation, pranic channel activation, ceremonial plant medicine use, trauma release breathwork, nervous system coherence chanting, biohacking consciousness optimization, mitochondrial and prana synergy Thank you to our sponsors! -Generation Lab | Go to http://generationlab.com/, use code Dave20 for $20 off, and see what your body’s really doing behind the surface. -Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off ...
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    51 m
  • Dead Water Is Making You Sick! (Biohacking Bonus Episode) : 1368

    Dead Water Is Making You Sick! (Biohacking Bonus Episode) : 1368
    Nov 24 2025

    Here’s the hidden story behind why you can chug “pure” water all day and still feel foggy, drained, and oddly thirsty: most of what we drink is missing something essential. In this video you’ll learn what “dead water” really is, how to tell if yours is part of the problem, and the simple shifts that keep your brain sharp, energy steady, and cells fully charged—without gimmicks, hype, or drinking a gallon a day.


    Chapters:


    00:00 – The “dead water” problem

    00:23 – Why minerals matter for your brain, heart & energy

    01:07 – 5,000 hydration scans: what the data shows

    01:33 – The 8-glasses myth (and who benefited)

    03:11 – Bottled water marketing vs reality

    04:17 – Tap water: safe ≠ complete

    06:00 – Hyponatremia: when “more water” backfires

    07:05 – Electrolytes your cells run on

    07:56 – What to do: filters, mineralizing, simple add-ins

    09:03 – Timing hydration + daily micro-habits


    Connect with Dave Asprey!



    Thank you to our sponsors!

    -LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser.

    -Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave.


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    Danger Coffee: https://dangercoffee.com/DAVE15

    Dave Asprey’s BEYOND Conference: https://beyondconference.com/

    Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

    Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15

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    14 m
  • 10-Minute Biohacking News Update : 1367

    10-Minute Biohacking News Update : 1367
    Nov 21 2025
    This episode covers: • Nano CBD Pain Relief Without Cognitive Side Effects A new nano-micelle formulation of CBD called CBD-IN delivers fast, non-addictive pain relief in mice without memory issues, motor impairment or the usual cannabinoid “fog.” Because it crosses the blood brain barrier and directly targets hyperactive pain circuits, it sidesteps many opioid-type drawbacks. Dave explains why precision-designed cannabinoids could reshape chronic pain treatment and longevity support. Source: https://www.sciencedaily.com/releases/2025/11/251117095652.htm • Moderate Calorie Restriction Slows Biological Aging A long-term trial from the National Institute on Aging found that cutting calories by about 12% over two years slowed the pace of aging — measured by methylation clocks and metabolic markers — in lean and mildly overweight adults alike. Dave breaks down why small, manageable dietary tweaks can deliver big longevity gains, without crash dieting or extreme fasting. Source: https://www.nia.nih.gov/news/cutting-calories-may-slow-pace-aging-healthy-adults • FDA Approves AI-Guided Robotic Surgery Trials for Alzheimer’s The U.S. Food and Drug Administration (FDA) has granted IDE approval for the first robotic microsurgical study targeting early stage Alzheimer’s disease using AI and deep imaging. The trial uses adaptive robotics to target deep brain lymphatic pathways, potentially clearing amyloid/tau deposits with surgical precision. Dave explains why this signals a new era in neurodegeneration – moving from drug-only to machine-assisted brain repair. Source: https://www.mmimicro.com/ide-approval-for-first-robotic-microsurgery-alzheimers-study/ • Antibiotic Reprograms Gut Bacteria to Produce Anti-Aging Molecules Researchers demonstrated that the veterinary antibiotic cephaloridine can reprogram gut microbes to secrete colanic acid — a molecule linked to better mitochondrial health, reduced gut permeability and improved cholesterol/insulin balance in mice. Dave explores how this could evolve into a pipeline of engineered probiotics that act as internal “longevity factories.” Source: https://newatlas.com/aging/antibiotic-longevity-microbiome/ (link remains unchanged) • Klotho: The Longevity Protein Nears Clinical Reality The longevity protein Klotho, known for clearing toxic by-products, calming inflammation and protecting brain/organ networks, is now advancing toward human trials via injectables, oral formats and gene therapy. Dave explains why Klotho is shaping up as a foundational target for next-gen age-reversal strategies and stacking protocols. Source: https://investingnews.com/longevity-focused-health-fueling-u-s-anti-aging-products-market-projected-to-reach-27-billion-by-2033/ (link remains unchanged) All source links provided for easy reference to the original reporting and research above. This episode is essential listening for fans of biohacking, human performance, functional medicine and longevity who want practical tools from Host ­Dave Asprey and the latest breakthroughs shaping the future of health. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade gives you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence and conscious living. New episodes are released every Tuesday, Thursday, Friday (audio only) and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: nano CBD, CBD-IN, pain relief research, non opioid pain therapies, chronic pain and aging, caloric restriction aging, methylation clocks, metabolic resilience, AI robotics, Alzheimer’s microsurgery, neurotech advancement, microbiome engineering, colanic acid, longevity probiotics, mitochondrial support, Klotho protein, anti aging gene therapy, cellular rejuvenation, longevity news, biohacking updates Thank you to our sponsors! LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. Vibrant Blue Oils | Grab a full-size bottle for over 50% off at https://vibrantblueoils.com/dave. Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com...
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    10 m
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Wealth of information from these podcasts. I binge these at work every single day.

Dave is the best

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I am so enlightened by cutting edge research and the years of experience and practice Dave has put in.

Top notch

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Great way to reframe wanting to pack everything in but figuring out what is best for you.

Info everyone needs to know!

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I am so excited to use these ideas and use the equipment and supplements I have already purchased and to tweak and add others. Thank you for this concise and valuable podcast! So excited to share this with loved ones that are stuck and looking for what to focus on next. This is a must listen episode!

Loved this episode! Reminded me and inspired me,!

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I’ve been listening to Dave Aspreys interviews for many years. I recommend his podcasts for anyone actively seeking health education.

Valuable health information!

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Hi Dave: I have survived life listening to your podcast. I started listening to you a couple years ago, & you bought me back to life. The first episode on analemma you did I immediately bought the wand I think it was October 2022. I take care of plants in office buildings & residents & I thought it would help some of my plants that seem not to take up nutrients from the soil. But it requires too much time to stir the water.
So when this episode came out about the whole house system I ordered it. also rebloom orchids & will use this system for it as well as my dogs & husband. I love the wand but am super excited for the whole house system, I know this will be another Hugh turning point in my life from you. Thank you so much for bringing this information to the world. You make this plant more amazing.


Kathy Dodd Green & Ever Growing

Analemma inspirations in my world

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Dave Asprey says, always learn the most you can so when you do make changes to your health in the best way and the most correct and complete way possible. So don't just listen to only one episode, more research and homework is always needed when trying to add or make changes to your health. The more you know!
I love Dave Asprey! I'm grateful!

listen and read more

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