The Human Upgrade: Biohacking for Longevity & Performance Podcast Por Dave Asprey arte de portada

The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

De: Dave Asprey
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For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.

Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.

This isn’t just self-improvement - it’s human enhancement backed by data.

Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.

Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

© Copyright © Bulletproof Media 2023 Ciencia Desarrollo Personal Higiene y Vida Saludable Éxito Personal
Episodios
  • Low Testosterone Starts In Your Eyes (Avoid This Before Bed) : 1416

    Low Testosterone Starts In Your Eyes (Avoid This Before Bed) : 1416
    Feb 15 2026

    https://truedark.com/discount/DAVETUBE


    Most people believe testosterone declines simply because of age. That explanation is easy, familiar, and wrong. Testosterone is not primarily controlled by how hard you train, how clean you eat, or how stressed you feel during the day.


    It is controlled by what happens in your brain at night. This video explains how sleep architecture works, why deep sleep is the foundation of hormone production, and how common nighttime habits flatten testosterone signals at the source.


    It also walks through practical ways to restore proper sleep timing, protect deep sleep, and rebuild the hormonal rhythm the body depends on.



    Timestamps:

    00:00 - Why testosterone decline is not just about aging

    01:12 - When testosterone is actually made in the body

    01:37 - Deep sleep explained (slow-wave sleep / N3)

    02:14 - “Fake aging”: why you feel older than you are

    03:35 - Why 8 hours of sleep can still fail you

    05:39 - How to protect deep sleep

    09:45 - How light at night confuses your brain’s clock

    12:11 - How to protect your eyes and sleep at night

    14:20 - What happens when sleep is finally fixed


    Thank you to our sponsors!

    • Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave.
    • EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.


    Resources:

    • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/

    • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.

    • Danger Coffee: https://dangercoffee.com/discount/dave15

    • My Daily Supplements: SuppGrade Labs (15% Off)

    • Favorite Blue Light Blocking Glasses: TrueDark (15% Off)

    • Dave Asprey’s BEYOND Conference: https://beyondconference.com

    • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

    • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/

    • Upgrade Labs: https://upgradelabs.com

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
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    14 m
  • Jet Lag Superdrug, 25% Dementia Drop, Coffee Brain Aging, Kratom Shakeup : 1415

    Jet Lag Superdrug, 25% Dementia Drop, Coffee Brain Aging, Kratom Shakeup : 1415
    Feb 13 2026
    This episode covers: • Mic-628 Could Reset Your Body Clock and Cut Jet Lag in Half A new circadian drug candidate, Mic-628, has demonstrated the ability to shift the body’s internal clock and significantly reduce jet-lag recovery time in early human studies. In controlled simulations, participants experienced faster realignment of their sleep-wake cycles and improved daytime performance compared to standard approaches like melatonin and light timing alone. Dave explains how this compound targets a core clock pathway, why eastbound travel is biologically harder than westbound, and how pharmacologic chronotherapy could become a serious performance tool for frequent travelers and shift workers. He also connects circadian alignment to obesity, insulin resistance, cardiovascular risk, and cognitive decline, outlining what this breakthrough could mean if safety data continues to hold. • Source: https://www.sciencedaily.com/news/top/ • Late-Life Depression May Signal Parkinson’s or Dementia New research from Shanghai Jiao Tong University found that new-onset depression in older adults is strongly associated with increased risk of Parkinson’s disease and dementia. Dave reframes this finding as a brain health signal rather than a purely psychiatric issue, explaining how inflammation, microglial activation, vascular health, and neurodegeneration intersect with mood changes. He breaks down why sudden depression in someone with no prior history may warrant deeper cognitive testing, sleep evaluation, and metabolic screening instead of simply prescribing an antidepressant and moving on. This story highlights the importance of treating mood shifts as early biological data in a longevity framework. • Source: https://www.sciencedaily.com/releases/2026/02/260210040623.htm • Speed-Training Brain Games Reduced Dementia Risk by 25 Percent The long-running NIH-funded ACTIVE trial found that a specific speed-of-processing training program reduced dementia incidence by roughly 25 percent over two decades. Unlike memory or reasoning exercises, this visual processing speed protocol produced measurable long-term protection. Dave explains why reaction time and processing speed may be core capacities tied to cognitive resilience, and how structured brain-training programs descended from this research can be treated like strength training for the mind. Instead of vague advice to “stay mentally active,” this data supports building deliberate, trackable cognitive training into a midlife longevity plan. • Sources: – NPR summary: https://www.npr.org/2026/02/09/nx-s1-5702423/modest-mental-exercise-can-reduce-risk-of-dementia-for-decades-study-finds – Psychology Today analysis: https://www.psychologytoday.com/us/blog/build-your-brain/202602/new-study-means-the-age-of-dementia-prevention-begins-now • Moderate Coffee Intake Linked to Slower Brain Aging A large analysis of roughly 130,000 participants found that moderate coffee consumption, about one to three cups daily, was associated with markers of slower brain aging and lower dementia risk. Dave explains why moderate, morning-weighted caffeine intake may align acute performance benefits with potential long-term brain protection. He breaks down the dose curve, why more is not necessarily better, and how to use coffee strategically without compromising sleep or circadian rhythm. Rather than framing caffeine as either a miracle or a villain, this study supports intelligent, personalized dosing as part of a broader brain-health stack. • Source: https://www.nature.com/articles/d41586-026-00409-y • Kratom Crackdowns and the Future of Supplement Freedom Regulators are tightening restrictions on high-potency kratom derivatives such as 7-hydroxymitragynine, with new bans and stricter warning requirements emerging at the state level. The FDA continues to treat kratom and its concentrated derivatives as unapproved drugs with opioid-like effects, while local jurisdictions are targeting specific formulations linked to adverse events. Dave breaks down how this represents a broader shift in how edge-case compounds are regulated, why supply volatility and underground markets can increase risk, and what this means for biohackers who experiment with gray-area tools. He also explains how evolving enforcement strategies could shape future access to peptides, nootropics, and other advanced compounds. • Sources: – Kansas City coverage: https://www.kshb.com/news/local-news/strong-high-weak-laws-7-oh-ban-kratom-regulation-moves-forward-in-kansas-city-missouri – Florida policy coverage: https://www.wgcu.org/health/2026-02-04/kratom-advocates-tout-its-properties-but-legislators-want-strict-warnings-about-the-herbal-supplement – Legal landscape analysis: https://www.lumalexlaw.com/2025/10/09/kratoms-legal-future-how-states-and-the-federal-government-are-responding/ – FDA background: https://www.fda.gov/news-events/...
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    10 m
  • Turn Off Your WiFi Tonight and See What Happens to Your Sleep : 1414

    Turn Off Your WiFi Tonight and See What Happens to Your Sleep : 1414
    Feb 12 2026
    Your phone, your lighting, and your WiFi can mess with your sleep and energy more than your diet, and this episode shows you the simplest fixes that actually move the needle. -Watch this episode on YouTube for the full video experience:https://www.youtube.com/@DaveAspreyBPR -Grab a generous discount from BONCHARGE by using code ‘DAVE’ on your next purchase: https://boncharge.com/ Host Dave Asprey sits down with Andy Mant, Co-Founder and CEO of BON CHARGE, and Katie Mant, Co-Founder and Chief Visionary Officer, to unpack how modern light, WiFi, and nonstop screen exposure are quietly shaping your sleep, hormones, and energy. After facing their own struggles with fatigue and poor sleep, they built BON CHARGE around science-backed biohacking tools designed to improve sleep, recovery, and overall wellness. They start with blue light at night and content overload, why light acts as biological information, and how simple changes like wearing blue light blocking glasses before bed can shift your circadian rhythm. The conversation moves into EMFs, native versus non-native frequencies, and what happened when they lived in an apartment flooded with WiFi and 5G. Dave shares his DEXA scan showing about 15% lower bone density where he used to carry his phone and explains why he now limits direct exposure. You’ll also get a practical breakdown of red light therapy and PEMF, including the difference between visible red and near-infrared light, how dosing affects results, and how mat-based PEMF is used to support relaxation and recovery. This episode stays grounded: you do not have to give up technology, you just have to learn how to hack your environment so it works for your biology instead of against it. You’ll Learn: • Why blue light at night can disrupt sleep and circadian rhythm • How light acts as information that shapes hormones and metabolism • Practical EMF reduction strategies you can test immediately • The difference between native and non-native EMFs • Red light vs near-infrared light and how each is used • Why dosing matters with red light therapy • What Dave noticed on his DEXA scan after years of carrying a phone • How PEMF mats aim to support relaxation and recovery Dave Asprey is a four time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. Thank you to our sponsors! • BEYOND Conference 2026 | Register now at https://beyondconference.com/ with code DAVE300 for $300 off • KillSwitch | Order at https://www.switchsupplements.com/ and use code DAVE for 20% off • Igniton | Head to https://igniton.com and use code DAVE for 15% off your first order • LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: blue light sleep, red light therapy benefits, EMF health effects, 5G radiation health, WiFiradiation exposure, circadian rhythm sleep, PEMF therapy mat, pulsed electromagnetic field therapy, near infrared light therapy, biohacking sleep optimization, mitochondrial ATP production, airplane mode at night, low EMF devices, Dave Asprey biohacking, BON CHARGE red light Resources: • BONCHARGE Website. Use Code ‘Dave’ For A Discount: https://boncharge.com/ • Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-biohacking-trends-report/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast ...
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    47 m
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Wealth of information from these podcasts. I binge these at work every single day.

Dave is the best

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I am so enlightened by cutting edge research and the years of experience and practice Dave has put in.

Top notch

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Great way to reframe wanting to pack everything in but figuring out what is best for you.

Info everyone needs to know!

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I am so excited to use these ideas and use the equipment and supplements I have already purchased and to tweak and add others. Thank you for this concise and valuable podcast! So excited to share this with loved ones that are stuck and looking for what to focus on next. This is a must listen episode!

Loved this episode! Reminded me and inspired me,!

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I’ve been listening to Dave Aspreys interviews for many years. I recommend his podcasts for anyone actively seeking health education.

Valuable health information!

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