The Human Upgrade: Biohacking for Longevity & Performance Podcast Por Dave Asprey arte de portada

The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

De: Dave Asprey
Escúchala gratis

OFERTA POR TIEMPO LIMITADO | Obtén 3 meses por US$0.99 al mes

$14.95/mes despues- se aplican términos.

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.

Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.

This isn’t just self-improvement - it’s human enhancement backed by data.

Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.

Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

© Copyright © Bulletproof Media 2023 Ciencia Desarrollo Personal Higiene y Vida Saludable Éxito Personal
Episodios
  • This Legal Boner Pill Is Hiding A Future Heart Attack : 1392

    This Legal Boner Pill Is Hiding A Future Heart Attack : 1392
    Jan 4 2026

    Most men think ED is just a performance issue. It’s not. It’s one of the earliest warning signs of cardiovascular decline and it often appears years before chest pain, shortness of breath, or heart attack symptoms.


    Thank you to our sponsors!

    -EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.

    -GOT MOLD? | Go to http://gotmold.com/shop and use DAVE10 to save 10% and see what’s in your air.


    Chapters

    00:00 - The “Legal Blue Pill” Myth & Hidden Danger

    00:57 - What ED Actually Is (Not the Commercial Version)

    01:45 - Circulation, Arteries & the Real Root Cause

    03:27 - The Problem with Relying on ED Pills

    05:03 - Treat ED as a Cardiovascular Symptom

    05:55 - Patterns That Reveal Vascular Decline

    07:10 - The ED–Heart Attack Countdown Window

    08:14 - How To Fix This Problem

    10:10 - Microdosing Cialis for Vascular Support

    10:45 - Aspirin as Another Option

    11:15 - Lifestyle Drivers of Vascular Damage & Solutions

    13:15 - Movement, Walking & Circulation Basics

    13:40 - The Mitochondria–Erection Connection

    15:00 - Recharging Mitochondria

    16:02 - Chronic Inflammation: The Silent Culprit

    17:17 - Smoking, Vaping, Obesity & Diabetes

    18:30 - How To Reduce Inflammation


    Resources:

    • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.

    • Danger Coffee: https://dangercoffee.com/discount/dave15

    • My Daily Supplements: SuppGrade Labs (15% Off)

    • Favorite Blue Light Blocking Glasses: TrueDark (15% Off)

    • Dave Asprey’s BEYOND Conference: https://beyondconference.com

    • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

    • Upgrade Collective: https://www.ourupgradecollective.com

    • Upgrade Labs: https://upgradelabs.com

    • 40 Years of Zen: https://40yearsofzen.com


    Connect with Dave Asprey!

    Website: https://daveasprey.com

    TikTok: https://www.tiktok.com/@daveaspreyofficial

    Instagram: https://www.instagram.com/dave.asprey/

    Facebook: https://www.facebook.com/Daveaspreyofficial/

    X: https://x.com/daveasprey

    YouTube: https://www.youtube.com/c/daveaspreybpr



    The Human Upgrade Podcast:

    Instagram: https://www.instagram.com/TheHumanUpgradePodcast/

    Facebook: https://m.facebook.com/Thehumanupgrade/

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
    Más Menos
    19 m
  • Biohacking News Weekly Update : 1391

    Biohacking News Weekly Update : 1391
    Jan 2 2026
    This episode covers: • Colon Cancer in the Young and Why Risk May Start in Infancy New reporting highlights a troubling rise in early-onset colon cancer, including cases in highly fit endurance athletes. Researchers identified a distinct DNA damage signature linked to colibactin, a toxin produced by certain strains of E. coli, with evidence suggesting the damage may occur in infancy. Dave explains why fitness alone isn’t protective, how early-life microbiome disruption and low-fiber modern diets stack long-term risk, and why earlier screening and gut-supportive habits like fiber, resistant starch, and circadian alignment matter more than ever. Source: https://www.businessinsider.com/why-so-many-young-people-getting-colon-cancer-answer-infancy-2025-12 • Kefir-Derived Bacteria, Immune Aging, and the Thymus A mouse study found that a kefir-derived bacterial strain, even when heat-inactivated, reduced age-related thymus shrinkage and lowered inflammatory signaling like IL-6. Dave breaks down why the thymus is central to immune aging, how chronic inflammation accelerates immune decline, and why your immune system responds to microbial signals, not just live probiotics. He explains how consistent fermented foods can act as immune training rather than a one-off supplement strategy. Source: https://economictimes.indiatimes.com/magazines/panache/popular-drink-can-reverse-aging-this-beverage-can-improve-immunity-and-help-achieve-longevity-finds-research/articleshow/126162250.cms • Why Vitamin D Doesn’t Work Without Magnesium A human trial shows that magnesium status strongly determines how vitamin D behaves in the body. Magnesium is required for the enzymes that activate vitamin D, and deficiency can block its effects. Dave explains why some people see no improvement despite supplementing vitamin D, how magnesium restored low levels and normalized high ones, and why nutrient networks matter more than megadosing a single vitamin. Source: https://www.sciencedaily.com/releases/2025/12/251228020010.htm • The Selenium Sweet Spot and Mortality Risk A large population analysis found a U-shaped relationship between dietary selenium intake and mortality. Low selenium increased all-cause and cardiovascular mortality, while higher intake offered no additional benefit and may increase risk. Dave explains selenium’s role in antioxidant defense, thyroid function, and immunity, why deficiency and excess are both problems, and how to approach selenium as a precision nutrient rather than a blanket supplement. Source: https://www.nature.com/articles/s41598-025-29228-3 • Time-Restricted Eating: Why the Window Matters More Than the Meal A randomized controlled trial compared early time-restricted eating, late time-restricted eating, and unrestricted eating. Both time-restricted groups naturally ate fewer calories without dieting, mainly by reducing snacking, while the unrestricted group drifted upward. Dave explains why the real benefit isn’t metabolic magic but behavioral control, how eating windows reduce decision fatigue and metabolic noise, and why consistency beats perfection when using time-restricted eating as a long-term tool. Source: https://www.nature.com/articles/s41467-022-28662-5 Keywords: early onset colon cancer, colon cancer in young adults, gut microbiome infancy, colibactin E. coli, precancerous colon polyps, fiber and colon health, kefir immune aging, fermented foods immunity, thymus aging, T-cell decline aging, IL-6 chronic inflammation, immune resilience longevity, vitamin D magnesium interaction, magnesium deficiency vitamin D, nutrient cofactor metabolism, vitamin D activation enzymes, selenium intake mortality, selenium deficiency risk, selenium over supplementation, antioxidant enzymes selenium, time restricted eating study, eating window metabolism, skip breakfast vs skip dinner, circadian eating patterns, behavioral calorie reduction, metabolic health biohacking, longevity science news Thank you to our sponsors! - BEYOND Conference 2026 | Register now at https://beyondconference.com/ -Timeline | Go to http://timeline.com/dave and get 35% off a subscription with their New Year offer. Resources: • Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://upgradelabs.com • 40 Years of Zen: https://40yearsofzen.com Timestamps: 0:00 – Intro 0:18 – Story #1: Colon Cancer in Young Athletes 1:40 – Story #2: Immune Aging and Microbial Signals 2:...
    Más Menos
    8 m
  • The Secret Federal Plan to Feed Us Legal Poison : 1390

    The Secret Federal Plan to Feed Us Legal Poison : 1390
    Jan 1 2026
    You’re about to learn how government approved food policies, regulatory loopholes, and corporate lobbying have quietly reshaped what’s allowed in the food supply and why these decisions are driving chronic inflammation, immune dysfunction, and neurological breakdown at scale. This episode exposes how biotoxins, ultra processed ingredients, and systemic regulatory failures contribute to long COVID, POTS, mold illness, chronic fatigue, and dysautonomia and why so many people feel sick despite following official health guidance. Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR Host Dave Asprey sits down with Dr. Will Cole, a functional medicine expert who works extensively with autoimmune disease, mold illness, hormonal dysfunction, digestive disorders, and complex brain related symptoms. Dr. Cole brings years of clinical experience analyzing lab data and treating patients with biotoxin exposure, neuro immune dysregulation, and chronic fatigue patterns. Together, they connect the dots between mold exposure, post viral illness, mast cell activation, low blood pressure, and why many people with long COVID or POTS feel dizzy, inflamed, and cognitively impaired. They explain how histamine overload, electrolyte depletion, cortisol imbalance, and genetics combine to disrupt blood flow to the brain and shut down human performance. The conversation focuses on practical functional medicine and biohacking tools that help rebuild resilience at the mitochondrial and nervous system level. You’ll Learn: • Why long COVID, mold illness, POTS, and chronic fatigue often share the same biological drivers • How biotoxins like mold and viral exposure dysregulate the neuro immune endocrine axis • Why low blood pressure reduces blood flow to the brain and causes brain fog and fatigue • What mast cell activation syndrome is and how histamine overload affects the body and brain • Why electrolytes, especially sodium, potassium, and magnesium, are foundational for recovery • How creatine supports brain energy, hydration, and mitochondrial function • The role of cortisol in inflammation, stress tolerance, and nervous system stability • When antihistamines and mast cell stabilizers can improve quality of life • How nicotine acts as a low dose neuroprotective compound when used carefully • The benefits and risks of methylene blue for mitochondrial and cognitive support • Why removing the trigger matters more than chasing symptoms • How a functional medicine approach rebuilds resilience instead of masking dysfunction • Why creatine absorption improves when added to hot coffee • How Danger Coffee fits into performance, hydration, and brain energy Thank you to our sponsors! - IGNITON | Go to http://igniton.com/ and use code DAVE for 15% off your first order. -TRU KAVA | Go to https://trukava.com/ and use code DAVE10 for 10% off. -Caldera + Lab | Go to https://calderalab.com/DAVE and use code DAVE at checkout for 20% off your first order. -LYMA | Go to https://lyma.sjv.io/gOQ545 and use code DAVE10 for 10% off the LYMA Laser. Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: long COVID, POTS syndrome, dysautonomia, mold illness, biotoxin illness, mast cell activation, histamine intolerance, low blood pressure brain fog, chronic fatigue syndrome, mitochondrial dysfunction, cortisol imbalance, electrolytes sodium potassium, creatine brain energy, functional medicine long COVID, nicotine neuroprotection, methylene blue mitochondria, brain fog causes, neuro immune dysfunction, will cole dave asprey, will cole biohacking Resources: • Dr. Will Cole’s Website: https://drwillcole.com/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey’s BEYOND Conference: https://beyondconference.com • Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Upgrade Collective: https://www.ourupgradecollective.com • Upgrade Labs: https://...
    Más Menos
    53 m
Todas las estrellas
Más relevante
Wealth of information from these podcasts. I binge these at work every single day.

Dave is the best

Se ha producido un error. Vuelve a intentarlo dentro de unos minutos.
I am so enlightened by cutting edge research and the years of experience and practice Dave has put in.

Top notch

Se ha producido un error. Vuelve a intentarlo dentro de unos minutos.
Great way to reframe wanting to pack everything in but figuring out what is best for you.

Info everyone needs to know!

Se ha producido un error. Vuelve a intentarlo dentro de unos minutos.
I am so excited to use these ideas and use the equipment and supplements I have already purchased and to tweak and add others. Thank you for this concise and valuable podcast! So excited to share this with loved ones that are stuck and looking for what to focus on next. This is a must listen episode!

Loved this episode! Reminded me and inspired me,!

Se ha producido un error. Vuelve a intentarlo dentro de unos minutos.
I’ve been listening to Dave Aspreys interviews for many years. I recommend his podcasts for anyone actively seeking health education.

Valuable health information!

Se ha producido un error. Vuelve a intentarlo dentro de unos minutos.
Ver más opiniones