Your Microbiome, GLP-1 & Next-Generation Probiotics | Dr. Colleen Cutcliffe

What if your metabolism, cravings, immune system — even your hormones — are being shaped by your gut?

In this episode of The Gabby Reece Show, Gabby sits down with microbiome scientist and Pendulum co-founder Dr. Colleen Cutcliffe to break down the real science behind gut health — beyond the buzzwords.

From premature birth and early antibiotic exposure to GLP-1, estrogen, cravings, and perimenopause, this conversation connects the dots between your microbiome and nearly every major system in your body.

If you’ve ever thought:

“Why am I gaining weight when nothing changed?”

“Why am I suddenly sensitive to foods?”

“Is this just aging… or something else?”

“Are GLP-1 drugs the only option?”

This episode will shift how you think about your body.

In This Episode, We Cover:

Why the microbiome is connected to all 11 organ systems

How early antibiotic use may affect long-term metabolic health

The truth about GLP-1 — and how your body produces it naturally

Why Akkermansia is considered a “keystone strain”

Gut health and perimenopause: what’s really happening

Estrogen, menopause, and emerging microbiome research

Why cravings may not be about willpower

How stress, aging, and travel deplete your gut

Fecal microbiome transplants — what they are and why they matter

How to rebuild a resilient gut (without extremes or shame)

Key Takeaway

The goal isn’t perfection.

It’s resilience.

A strong, diverse microbiome helps your body handle stress, hormonal shifts, aging, and even dietary slip-ups. And unlike your genetics — your gut can change.

Start with food.

Use tools wisely.

Pay attention to your body.

Connect with Dr. Colleen Cutcliffe

Website: https://pendulumlife.com

Instagram: @pendulumlife

Dr. Cutcliffe on Instagram: @drcolleencutcliffe

Connect with Gabby

Website: https://gabbyreece.com

Instagram: @gabbyreece https://www.instagram.com/gabbyreece

YouTube: The Gabby Reece Show https://www.youtube.com/@GabbyReece

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