Why We Store Fat Differently: The Science Behind Metabolism and Obesity with Dr. Kafi Ealey

Research shows that adipose (fat) tissue isn’t just stored energy—it plays a critical role in metabolism, inflammation, and disease risk. Biological, environmental and nutritional factors contribute to differences in how people store fat and develop conditions such as obesity and type 2 diabetes. Dr. Kafi Ealey is an assistant professor in the School of Nutrition at Toronto Metropolitan University. Dr. Ealey obtained her MSc and PhD from the Department of Nutritional Sciences at the University of Toronto and completed postdoctoral training at the RIKEN Center for Integrative Medical Sciences in Yokohama, Japan, as well as in the Department of Translational Medicine at the Toronto Hospital for Sick Children Research Centre. Dr. Ealey’s research is focused on understanding the biological and cellular processes that govern the diverse functions of metabolic tissues to promote overall health. Her work employs a range of experimental models to determine how nutrition can affect fat storage, the immune system, and how the body uses energy, and helps us better understand how to prevent or manage chronic metabolic diseases. Dr. Ealey is particularly passionate about examining the biological variations in metabolic systems that contribute to racial and ethnic disparities in the prevalence of obesity-related conditions, including type 2 diabetes. In this episode, Dr. Ealey discusses how fat storage and metabolism vary across individuals and populations, and why these differences matter for health.