Did you know there's a new way doctors may diagnose obesity? For decades, obesity has been defined simply by your BMI number, but leading experts are now proposing a more comprehensive approach that looks beyond just weight and height.

Join Holly and Jim as they welcome Dr. Eric Ravussin, a renowned physiologist from the Pennington Biomedical Research Center who has spent over 40 years studying human metabolism and weight regulation. They explore how this new obesity definition could transform treatment approaches, insurance coverage, and our understanding of weight-related health risks. You'll also hear about the groundbreaking research with Pima Indians that shows the interaction between genetics and environment in weight regulation.

Whether you're struggling with weight issues or simply interested in the science of metabolism, this episode offers insights into how medical professionals might soon approach obesity diagnosis in a more personalized and effective way.

• Why BMI alone isn't enough to diagnose obesity (and what metrics may replace it)
• The key difference between "preclinical" and "clinical" obesity in the new definition
• How this new classification system might affect insurance coverage and medication access
• The powerful interaction between genetics and the environment in the study of two Pima Indian populations
• Why your metabolism might matter more than previously thought (but not in the way you expect)
• The physiological importance of not eating all day long
• Dr. Ravussin's bold thoughts on what environmental changes might actually reduce obesity rates

• The Lancet Diabetes & Endocrinology Commission Definition and diagnostic criteria of clinical obesity
• Study Design of the Maycoba Project: Obesity and Diabetes in Mexican Pimas

Intermittent fasting has become one of the most popular weight loss strategies but does it work better than traditional calorie restriction? This burning question finally has an answer, thanks to a groundbreaking year-long clinical trial.

Join Holly and Jim as they interview Victoria Catenacci, the lead researcher behind this landmark study on 4:3 intermittent fasting. As a physician and clinical researcher at the University of Colorado Anschutz Medical Campus, Dr. Catenacci has spent years investigating whether eating very little three days a week (while eating normally the other four days) produces better results than daily calorie restriction. After seven years of research, the results are finally in – and they might surprise you.

• What 4:3 intermittent fasting means (and how it differs from other fasting methods)
• The surprising finding about which approach produced more weight loss after one year
• Why women seemed to benefit more from intermittent fasting than men
• Whether fasting three days a week leads to muscle loss compared to daily restriction
• The truth about whether intermittent fasting triggers binge eating behaviors
• The unexpected finding about which approach might be easier to stick with in the long-term
• How to safely exercise on fasting days versus non-fasting days
• The simple strategy that made fasting days more manageable for study participants

This conversation cuts through the hype to reveal what science says about intermittent fasting for sustainable weight loss. Whether you're curious about trying fasting or want evidence-based weight management strategies, this episode delivers valuable insights from the researcher who led this revolutionary study.

Are you moving enough? While many of us focus on weight loss goals, we're often missing a critical piece of the puzzle: our drastic decline in daily movement. In this episode, Holly and Jim reveal how physical activity has quietly disappeared from our lives over the past decades.

Did you know that in the 1960s, people burned 300-400 more calories daily without ever setting foot in a gym? Join Holly and Jim as they explore America's "physical activity report card" and share startling statistics about how technology and modern lifestyles have engineered movement out of our daily routines. You'll discover practical strategies to reclaim physical activity in a world designed for sitting.

• How work and transportation-related movement has drastically declined since the 1960s
• Why meeting the recommended 150-300 minutes of weekly activity is harder than you think
• The three critical buckets of physical activity you need to consider
• Why strength training is the most overlooked form of exercise (with a surprising home "gym" equipment everyone owns)
• Personal challenges Jim and Holly face with staying active
• Why high-energy living (more calories in AND out) is easier to maintain than low-energy living