This Week in Cardiology Podcast Por Medscape arte de portada

This Week in Cardiology

This Week in Cardiology

De: Medscape
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This podcast delivers Dr. John Mandrola's summary and perspective on top news of the week that cardiologists can't miss. This podcast is intended for US health professionals only.Copyright 2019, Medscape Ciencia Enfermedades Físicas Higiene y Vida Saludable
Episodios
  • Dec 12 2025 This Week in Cardiology

    Dec 12 2025 This Week in Cardiology
    Dec 12 2025

    An elegant study in post-TAVI atrioventricular block, a PSA for my structural colleagues, revascularization in women, and a CTO PCI trial are the topics John Mandrola, MD, discusses in this week's podcast.

    This podcast is intended for healthcare professionals only.

    To read a partial transcript or to comment, visit:

    https://www.medscape.com/twic

    I AV Block After TAVR

    Heart Blocks During vs After TAVR Show Distinct Patterns

    https://www.medscape.com/viewarticle/heart-blocks-during-vs-after-tavr-show-distinct-patterns-2025a1000ypp

    • Mechanisms Underlying Alterations in Cardiac Conduction After TAVR https://jamanetwork.com/journals/jamacardiology/fullarticle/2842748

    II Related PSA Announcement to My Structural Colleagues

    III Revascularization Strategies in Women with Severe Chronic CAD

    Women With Chronic Severe CAD Fare Better With CABG vs PCI

    https://www.medscape.com/viewarticle/women-chronic-severe-cad-fare-better-cabg-vs-pci-2025a1000ygd

    • PCI vs CABG in Women With Chronic CAD https://doi.org/10.1093/eurheartj/ehaf806
    • PCI vs CABG - Meta-Analysis of 4 RCTs https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02334-5/abstract
    • CABG vs Drug-Eluting Stent Implantation for CAD - Meta-Analysis https://www.jacc.org/doi/10.1016/j.jcin.2016.10.008
    • RECHARGE trial https://therechargetrial.com/

    IV A CTO PCI RCT – But don't get your hopes up

    • Early vs Late-Staged PCI After Subintimal Tracking and Re-entry for CTO https://doi.org/10.1016/j.jacc.2025.09.1598
    • DECISION CTO trial https://pubmed.ncbi.nlm.nih.gov/30813758/
    • National Inpatient Sample Database PCI CTO Associated With Higher Mortality https://pubmed.ncbi.nlm.nih.gov/37356643/

    V Mandrola's Top 10 Stories

    You may also like:

    The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

    Questions or feedback, please contact news@medscape.net
    Más Menos
    28 m
  • Dec 05 2025 This Week in Cardiology

    Dec 05 2025 This Week in Cardiology
    Dec 5 2025

    Less is more after PCI, the TARGET-FIRST trial, a negative blood pressure trial that is actually positive, aspirin vs OAC for bleeding, AEDs, and Factor XI is not dead yet are the topics discussed by John Mandrola, MD, on this week's podcast.

    This podcast is intended for healthcare professionals only.

    To read a partial transcript or to comment, visit:

    https://www.medscape.com/twic

    I Less is More: TARGET-FIRST

    • TARGET-FIRST Trial https://www.nejm.org/doi/10.1056/NEJMoa2508808
    • STOPDAPT-2 ACS Trial https://jamanetwork.com/journals/jamacardiology/fullarticle/2789701

    II A Negative Trial That Is Actually Positive

    • The RETREAT-FRAIL Study https://www.nejm.org/doi/full/10.1056/NEJMoa2508157

    III Major Bleeding With Aspirin vs Apixaban

    • Subanalysis of ARTESiA https://jamanetwork.com/journals/jamacardiology/fullarticle/2841075
    • ARTESiA Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2310234
    • AVERROES Trial https://www.nejm.org/doi/full/10.1056/NEJMoa1007432

    IV High Value Interventions – The AED

    • Experts Call for AED Placement on All Commercial Aircraft https://www.medscape.com/viewarticle/experts-call-aed-placement-all-commercial-aircraft-2025a1000xzf
    • In-Flight Sudden Cardiac Arrest and AED Use 10.1016/j.cjca.2025.10.010 External Link

    V Factor XI Inhibitors – OCEANIC STROKE trial

    • Bayer Press Release on Asundexian https://www.bayer.com/en/us/news-stories/oceanic-stroke

    You may also like:

    The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

    Questions or feedback, please contact news@medscape.net
    Más Menos
    30 m
  • Nov 21 2025 This Week in Cardiology

    Nov 21 2025 This Week in Cardiology
    Nov 21 2025

    Listener feedback, huge news in the world of carotid disease with the CREST-2 publication, prasugrel beats ticagrelor again, and a big coffee trial are the topics John Mandrola, MD, discusses in this week's podcast.

    This podcast is intended for healthcare professionals only.

    To read a partial transcript or to comment, visit:

    https://www.medscape.com/twic

    I Listener Feedback

    • Complete Revascularization for Acute MI Meta-analysis https://doi.org/10.1016/S0140-6736(25)02170-1

    II A Sea Change in the Treatment of Carotid Artery Disease — CREST-2 Published

    • ECST-2 https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00107-3/fulltext
    • SPACE-2 https://pubmed.ncbi.nlm.nih.gov/36115360/
    • CREST-2 Trial www.nejm.org/doi/full/10.1056/NEJMoa2508800
    • CREST Protocol paper https://pmc.ncbi.nlm.nih.gov/articles/PMC5987521/

    III Prasugrel Beats Ticagrelor in High-Risk Patients With Diabetes After PCI https://www.medscape.com/viewarticle/prasugrel-beats-ticagrelor-high-risk-patients-diabetes-after-2025a1000wbt

    • PLATO trial https://www.nejm.org/doi/full/10.1056/NEJMoa0904327
    • Ticagrelor or prasugrel vs clopidogrel in PCI https://eurointervention.pcronline.com/article/ticagrelor-or-prasugrel-versus-clopidogrel-in-patients-undergoing-percutaneous-coronary-intervention-for-chronic-coronary-syndromes
    • ISAR-REACT 5 trial https://www.nejm.org/doi/full/10.1056/NEJMoa1908973

    IV Another Coffee and AF study

    Can Coffee Cut the Risk for Atrial Fibrillation?

    https://www.medscape.com/viewarticle/can-coffee-cut-risk-atrial-fibrillation-2025a1000w11

    A Coffee a Day to Keep the AFib Away? The DECAF Trial Discussed https://www.medscape.com/viewarticle/coffee-day-keep-afib-away-decaf-trial-discussed-2025a1000v5z

    • DECAF trial https://jamanetwork.com/journals/jama/fullarticle/2841253

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    The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

    Questions or feedback, please contact news@medscape.net
    Más Menos
    29 m
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Dr Mandrola delivers excellent updates on recent publications. The podcast is just the thing for a commute: not too superficial, not too detailed, and do a great job placing the new clinical advances in the context of contemporary practice.

recommend to colleagues

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As a former Cardiology PA now working on the academic side of medicine, I’ve been out of practice for several years. Preparing to teach a cardiology course at a new program, I started brushing up on material—and stumbled across Dr. Mandrola’s podcast. Wow. I wish I had known about this resource back when I was still practicing clinically.

In just a short time, I’ve learned what’s new since I left practice, and even picked up on things I probably should have known better back then. More importantly, I’ve gained an entirely new appreciation for how to critically review clinical trials and recognize bias.

What sets this podcast apart is Dr. Mandrola’s humility and honesty: his willingness to point out flaws in studies, to admit when he doesn’t know something, and to change his perspective when the evidence supports it. That kind of intellectual honesty builds trust, and it makes him feel less like a distant expert and more like a fellow learner walking through the field with you.

I’ve flown through the last two years of episodes in just a week, and I’m looking forward to being a dedicated listener moving forward. Thank you, Dr. Mandrola, for approaching cardiology not as a lecture, but as a thoughtful, ongoing conversation.

Honest, Insightful, and Incredibly Valuable

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I absolutely love listening to this podcast and feel I practice medicine very similarly. I love your critical review of studies as it brings these areas to light. I especially loved your comment at the end of this podcast discussing the reasoning to go into EP. I agree with your reasons, and consider them the same for most fields of medicine, especially any in cardiology, which I practice as a PA in and have for 14 years. Going into medicine just for the money should never be the reason as it will only lead to frustration and burnout. Thank you for your honest reviews and feedback each week.

EP is not about the money -love this statement

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Me gusta el escepticismo del Dr Mandrola. Habla de su objetividad y su compromiso con la ciencia bien hecha

Muy informativo

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