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Summary

In this episode, Ed Delesky, MD, and Nicole Aruffo, RN, discuss the impact of GLP-1 medications on lean body mass and muscle mass during weight loss. They explore definitions of lean body mass and skeletal muscle mass, the effects of weight loss medications on muscle physiology, and strategies to preserve muscle mass through diet and exercise. The conversation emphasizes the importance of understanding muscle quality and the potential risks of sarcopenia, particularly in vulnerable populations. The episode concludes with practical advice for maintaining muscle health while using weight loss medications.

Takeaways

GLP-1 medications can impact muscle mass during weight loss.
Lean body mass includes all tissues except fat.
Skeletal muscle mass is crucial for strength and metabolism.
Different studies show varying impacts of GLP-1 on muscle mass.
Weight loss can lead to reduced resting energy expenditure.
Muscle quality is an important factor in health outcomes.
Sarcopenia may be concern for older adults on weight loss medications.
Increasing protein intake can help preserve muscle mass.
Resistance training is essential for maintaining muscle strength.
Consult your doctor for personalized dietary and exercise advice.

Keywords

weight loss, GLP-1 medications, muscle mass, lean body mass, obesity, health, nutrition, exercise, patient education, diabetes, zepbound, wegovy, ozempic, mounjaro

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Production and Content: Edward Delesky, MD & Nicole Aruffo, RN
Artwork: Olivia Pawlowski