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Welcome back to the Hotflash inc podcast, hosted by journalist and founder Ann Marie McQueen – the only reader-supported, evidence, expert opinion and human experience-based platform dedicated to all aspects of menopause and midlife. Today’s guest is Jennifer Block, an independent investigative journalist based in the United States. who reports on medicine, health, science and power. In this episode, Ann Marie and Jennifer explore the rising tide of estrogen-focused messaging in menopause care – and how it might not be as organic or evidence-based as it seems. Jennifer has just published three major articles — in The Free Press, The British Medical Journal and on her Substack Unpopular Science — that connect long-suspected dots between pharma-backed advocacy, conflicts of interest and the shifting tone around hormone therapy. Together, these pieces paint a picture of an industry-backed campaign influencing policy, public opinion, and clinical guidance. If you’ve been wondering why estrogen is suddenly everywhere, this is the conversation you’ve been waiting for.

Sponsor Shoutout: Thank you to our sponsor, Timeline Nutrition – makers of Mitopure™, the first clinically tested Urolithin A supplement that supports cellular energy and muscle strength. Visit www.timeline.com and use the code HOTFLASH for 20% off your first order.

Also, thank you to our friends at Bonafide. Visit hellobonafide.com and use code SUMMIT20 to receive 20% off your first month of any Bonafide subscription product.

Highlights

• How Jennifer’s recent reporting was sparked by the FDA black box warning change
• The behind-the-scenes forces pushing for estrogen’s big comeback
• Why the “menopause awareness movement” isn’t as grassroots as it seems
• What Jennifer uncovered about the industry ties behind the Menopause Society
• Why many doctors may not be aware of their own industry entanglements
• How these dynamics affect everyday women making decisions about HRT
• What informed consent really means in this climate
• The importance of journalistic scrutiny in medical debates

Fact check:

• Addyi (flibanserin) offers a modest benefit for certain premenopausal women with HSDD (hypoactive sexual desire disorder), averaging 0.5 to 1 additional satisfying sexual event per month compared to placebo.
• Compounded hormones typically do not carry standardized FDA boxed warnings or package inserts. These customized medications are exempt from federal labeling regulations, meaning key risk information may not be included.

About Jennifer

• Website: www.jenniferblock.com
• Substack: Unpopular Science

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In this episode of the Hotflash inc Podcast, host and journalist Ann Marie McQueen is joined by Dr. Rachel Pope, an OB-GYN, certified menopause practitioner, and urologist at University Hospitals Cleveland Medical Center, with an appointment in the Department of Reproductive Biology. Dr. Pope is also a public health researcher, currently working to clarify gaps in hormone therapy research that impact real women every day.

Dr. Pope’s recent study set social media on fire, with claims that hormone therapy in perimenopause reduces breast cancer, stroke, and heart attack risk by 60%. But is that actually what the data said? In this episode, Dr. Pope gives a clear, honest account of what her study really found – and what it didn’t. She speaks about the confusion that followed, why nuance matters, her belief in the power of hormone therapy and how to move forward in the menopause conversation with more care, accuracy and integrity.

This is a must-listen for anyone navigating perimenopause, hormone therapy decisions or working in the midlife health space.

Sponsor Shoutout

Thank you to our sponsor, Timeline Nutrition – makers of Mitopure™, the first clinically tested Urolithin A supplement that supports cellular energy and muscle strength. Visit www.timeline.com and use the code HOTFLASH for 20% off your first order.

Thank you to Bonafide, a gold sponsor at the Hotflash Inc Summit. To learn more, visit hellobonafide.com and be sure to use code SUMMIT20 to receive 20% off the first month of any Bonafide subscription product.

Highlights

• The truth behind the viral claim that hormone therapy “reduces risk by 60%.”
• Why misinterpretation of data spreads so fast — especially on social media.
• What the research actually says about breast cancer, stroke, and heart attack.
• The gaps in current evidence, especially around compounded hormones and long-term outcomes.
• How healthy-user bias and retrospective databases can distort study results.
• Why individualized care matters — and why hormone therapy isn’t universally preventative.

GUEST LINKS

• University Hospitals Cleveland Medical Center
• Instagram: @drrpope
• X: @drrpope

Join the Hotflash inc perimenoposse:

Web: hotflashinc.com
Newsletter: Hotflash inc. on Substack
TikTok: @hotflashinc
Instagram: @hotflashinc
X: @hotflashinc

Episode website: Hotflashinc

Listen on: Apple Podcasts | Spotify | Google Podcasts | YouTube | Substack

See hotflashinc.com/privacy-policy for privacy information

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In this solo episode of the Hotflash inc Podcast, host and founder Ann Marie McQueen dives into the rising conversation around ADHD and perimenopause. Drawing from personal experience, research, and lived insight, Ann Marie explores how midlife hormone shifts may intersect with neurodivergence – and how confusing, frustrating and illuminating that process can be. This episode is a candid, powerful reflection on mental health, executive function and how being a woman in midlife calls for compassion and curiosity.

Thank you to our sponsor, Timeline Nutrition – makers of Mitopure™, the first clinically tested Urolithin A supplement that supports cellular energy and muscle strength. Visit www.timeline.com and use the code HOTFLASH for 20% off your first order.

Highlights

• Ann Marie reflects on the constant battle to get information right in a world full of misinformation.
• The emerging connection between perimenopause, ADHD, and hormonal changes.
• Research shows ADHD traits can intensify menopausal symptoms—even in undiagnosed women.
• Ann Marie shares her own experience recognizing lifelong ADHD tendencies.
• Sensory sensitivity, rejection sensitivity, and how they show up in midlife.
• Why she hasn’t pursued an official diagnosis – and how nervous system healing has helped.
• The pain of not being taken seriously when you open up about neurodivergence.
• Testosterone’s overlooked role in executive function and how HRT may help.
• Why a holistic approach is essential for navigating neurodivergence in midlife.
• The power of being seen and heard – how a simple conversation at work changed everything.

This podcast is hosted by Ann Marie McQueen, journalist and founder of Hotflash inc, the world’s only reader-supported, research-based platform covering all aspects of menopause and midlife. With more than 30 years in journalism, Ann Marie provides evidence-based content, expert interviews, and deeply personal conversations to help women around the world navigate this pivotal life stage.

If you enjoyed this episode, please share it with someone who might benefit – and don’t forget to subscribe, rate, and review the show. To get the latest research and real talk on perimenopause, menopause, and midlife straight to your inbox, subscribe to the Hotflash inc newsletter at hotflashinc.com.

Join the Hotflash inc perimenoposse:

Web: hotflashinc.com
Newsletter: Hotflash inc. on Substack
TikTok: @hotflashinc
Instagram: @hotflashinc
X: @hotflashinc

Episode website: Hotflashinc

Listen on: Apple Podcasts | Spotify | Google Podcasts | YouTube | Substack

See hotflashinc.com/privacy-policy for privacy information