TWiV 1275: An amazing sequence and a gutsy therapy

TWiV explains the Nobel Prize-winning discovery of pre-mRNA splicing, and engineering bacteriophage to deliver proteins to the human intestine.

Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker

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Links for this episode

• Support science education at MicrobeTV
• Immune 100 live at the Incubator
• Spliced segments of adenovirus mRNA (PNAS)
• An amazing sequence in adenovirus mRNA (Cell)
• Nobel Prize for mRNA splicing (Nobel)
• A predominant undecanucleotide in adenovirus late mRNAs (Cell)
• Splicing RNA with Phillip A. Sharp (ASM)
• Protein production in the gut by engineered phage (Nat Biotech)
• Engineered phage T4 (Curr Op Virol)
• Timestamps by Jolene Ramsey. Thanks!

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Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.