Reason, co-founder and CEO of Repair Biotechnologies and a longevity industry veteran with a background in astrophysics, joins us to talk about what it actually takes to test a therapy on humans, and why the system built to protect patients often keeps the best evidence hidden.

He breaks down why investors backing gene and cell therapies care more about a drug’s earning potential than whether it works, and why treatments already in use could be quietly adding years to human lifespan without anyone confirming it. Drawing on his own experience as a trial participant in Roatán, he also explains why Australia has become a faster, cheaper alternative for clinical trials, and how much of that gap comes down to culture rather than actual safety.

More about Reason’s work:

* Fight Aging!

Tim Urban, creator of Wait But Why and the mind behind one of the most-watched TED Talks of all time, joins us to talk about why progress does not happen automatically.

In this episode, he discusses the Space Race, longevity, AI safety, startup cities, and the social conditions that allow new ideas to survive. Tim explains why some technologies move fast while others stall for decades, why the best communities treat ideas like experiments, and why the future may depend less on prediction and more on building better environments for progress.

More about Tim Urban’s work:

* Tim Urban’s X

* What’s Our Problem?: A Self-Help Book for Societies

Antonio Garcia Martinez is a writer, entrepreneur, and director at Base, Coinbase’s Ethereum L2. Before that he sold a startup to Twitter, worked on ads at Facebook, and wrote Chaos Monkeys, his memoir about the early ad-tech world.

This session was recorded live in the Infinity Dome in Prospera. Antonio explains why crypto is not just a new financial system. It is a direct challenge to one of the oldest powers of the state: controlling money and deciding who owns what. If you can send USDC on Base to anyone in the room in less than a second for less than a cent, and no bank or government can stop it, the foundations of the current world start to shift.

From there, we move into the friction between digital freedom and physical geography. Antonio, Niklas and Eric talk about Próspera as a real world network state, why San Francisco stays a magnet even when it fails on the basics, and which places have the energy to become new tech hubs. Miami, Dubai, Singapore, and the American West all come up as examples. They also look at the hard questions: how to build a business model for charter cities, how the US might allow Prospera-style zones through interstate compacts, and what needs to change in education and citizenship to attract long-term residents.

This is a conversation about the future of crypto, but also about the future of how people live, build, and move. It is one of the clearest snapshots of where the network state movement is heading.

More about Antonio’s work:

* Website

* Books

* Linkedin

Explore Infinita City:

* Explore the Archive: The Infinita City Times

* Visit Infinita City

* Join the Builders’ Hub on Telegram

* Follow Infinita City on X