Spray Away Severe Depression

When severe depression becomes treatment-resistant depression, an unconventional medication is proving to be effective. It’s a specific form of ketamine that is administered by nasal spray in a supervised clinical setting, approved by the FDA for this purpose. Dr. Caleb Battersby, director of interventional psychiatry at UConn Health, explains how esketamine works and why this treatment approach has been providing hope for those who otherwise may be out of answers.

(Dr. Caleb Battersby, Carolyn Pennington, Chris DeFrancesco, April 2025, studio and technical support by Ethan Giorgetti and Ryan Bernat)

Dr. Caleb Battersby https://facultydirectory.uchc.edu/profile?profileId=Battersby-Caleb

UConn Health Department of Psychiatry https://health.uconn.edu/psychiatry/

Find a treatment center https://www.spravato.com/find-treatment-center/

UConn Health Minute: Treating Severe Depression (December 2024) https://today.uconn.edu/2024/12/uconn-health-minute-treating-severe-depression/