Let’s dive into the AI-powered future of fragrance—where machines are learning to predict, design, and even manipulate scent in ways we never imagined. Can artificial intelligence outsmart human perfumers? Why do some perfumes last for hours while others vanish in minutes? How are brands using captive molecules and trade secrets to lock out competitors and control the industry? Maria Meliora asks Rich Whitcomb from Osmo to reveal how neural networks and molecular data are mapping chemistry to scent perception. We explore the puzzles of longevity, the role of “silent enhancers,” and hear hot takes on useful vs. overrated molecules like Iso E Super, Ambroxan, and pheromone marketing—plus what even the almighty AI still struggles with. If you’ve ever wondered why perfume dupes never smell quite right, why some ingredients mysteriously disappear, or what the next Chanel No. 5 for Gen Alpha might be, this episode is for you.🔥 Challenge our guests! They’re eager to hear your burning questions and concerns about AI, perfumery, and the future of scent. Drop a comment or review!0:00:00 AI & Fragrance: The Future of Perfumery Begins Here0:01:30 Meet Richard Whitcomb: AI & Deep Learning Expert at Osmo0:03:23 Can AI Really Predict How a Perfume Will Smell?0:05:04 The Hidden Problem: Why the Perfume Industry Lacks Open Data0:07:03 Trade Secrets & the Challenges of Becoming a Perfumer0:09:18 Molecular Structure vs. Smell: The Unpredictable Science Behind Fragrance0:10:59 Vibrational Theories, Shape Theories & The Mystery of Olfaction0:12:59 How Does AI Actually Model Smell?0:15:15 Graph Neural Networks: The Secret to AI-Based Fragrance Creation?0:17:03 Are AI Scientists Just “Monkeys With Magic Boxes”?0:19:28 Why Different AI Models Dominate Different Fields0:21:35 Can We Ever Train AI to Think Like a Perfumist?0:24:54 Why Are Aromatic Molecules So Small? The Science of Volatility0:26:28 Embeddings, Perception & The Subjectivity of Smell0:29:12 Can AI Solve the “Clean Smell” Debate Once and for All?0:31:22 The Nightmare of Modeling Perfume Mixtures0:33:39 Silent Enhancers: The Hidden Forces That Shape Scent Perception0:36:18 Fixatives, Blooming Agents & The Chemistry of Longevity0:38:08 The Truth About Fragrance Layering & Why It Works0:39:44 The Iso E Super Debate: Silent Queen or Naked King?0:41:04 Ambergris & Ambroxan: Magnificent Beast or Nose Destroyer?0:42:24 Are Long-Lasting Perfumes a Hidden Environmental Hazard?0:44:21 The Future of Safe & Sustainable Fragrance Ingredients0:46:08 Hedione & Pheromones: Fact or Fiction?0:48:05 Fiskool & The Rise of Patented Aroma Molecules0:50:15 Are Captive Molecules the Future of Perfumery?0:52:25 Can New AI-Created Molecules Make Perfume More Creative?0:53:48 The Intellectual Property War Over Synthetic Fragrances0:55:55 Why Do Perfume Dupes Never Smell Quite Right?0:57:31 Synthetic vs. Natural: The Great Fragrance Debate1:00:39 Is AI Going to Replace Perfumers?1:02:20 The Future of Perfumery: What AI Can (and Can’t) Do1:04:16 Will Perfumers Become More Like Conceptual Curators?1:06:05 Are AI-Generated Perfumes Just Parrots of the Past?Guest Info:Website: https://www.osmo.ai/ Contact: fragrance@osmo.ai LinkedIn: https://www.linkedin.com/company/osmolabs/X: @osmo_labs IG: @osmo_labsSniff for yourself: https://www.melioraparfums.com/shopThank you for your trust and support, see you soon in the next video 💋Contribute to keep our community going: https://www.melioraparfums.com/checkout/donate?donatePageId=643dc3d558b7446e3e36b115Contact Info:Social media: @pefume.nation.podcast, @meliora.mariaOfficial Website: https://melioraparfums.comFashion + Aerial Arts: www.aerialgoth.com✍ Channel's Address: Maria Meliora P.O. Box 28279 Kenneth City, FL 33709✍ Email: info@melioraparfums.com