SIBO and IMO: Understanding Gut Overgrowth, Methane, and Archaea

In this follow-up to one of our most popular episodes, host Jacqueline Gaulin welcomes back Dr. Mark Pimentel, Executive Director of the Medically Associated Science and Technology (MAST) Program at Cedars-Sinai, to dive deeper into the science behind SIBO (Small Intestinal Bacterial Overgrowth) and IMO (Intestinal Methanogen Overgrowth).

Dr. Pimentel answers listener questions and explains how these complex conditions relate to IBS-D and IBS-M, why methane and archaea matter for gut health, and how motility and the Migrating Motor Complex (MMC) play a crucial role in prevention and treatment. You'll also learn about the latest insights and therapeutic approaches that can help patients find lasting relief.

Produced in collaboration with the American College of Gastroenterology's Patient Care Committee, this evidence-based discussion helps you better understand the "why" behind SIBO and IMO—and what steps you can take toward better gut health.