Overview: Explore the evolving landscape of Alzheimer’s diagnosis, where blood tests are emerging as a critical tool in clinical practice. In this episode, we’ll examine how these tests add value to traditional diagnostic methods and the latest research validating their accuracy. Join us to discover the potential of blood tests in transforming Alzheimer’s diagnosis. Guest: Suzanne E. Schindler, MD, PhD, Associate Professor of Neurology, Washington University School of Medicine For more information, please visit: https://www.pri-med.com/clinical-resources/podcast/ceoi-alzheimers-diagnostics-pt-1

Overview: With the foundational knowledge from Episode 1, we transition from theory to practice. As these diagnostic tools become more widespread, primary care clinicians are at the forefront of their implementation. Listeners will gain insights from real-world experiences, learning actionable strategies to overcome challenges such as logistical barriers and resource limitations. By the end of this episode, primary care clinicians will have a roadmap for implementing blood tests into their practice. Guest: Deanna Willis, MD, MBA, FAAFP, FNAP; Jared Brosch, MD For more information, please visit: https://www.pri-med.com/clinical-resources/podcast/ceoi-alzheimers-diagnostics-pt-2

Overview: As blood tests for Alzheimer’s become more accessible, clinicians must navigate the ethical and emotional complexities of delivering life-changing results. We explore how to communicate these findings with care, manage the psychological impact on patients and families, and address uncertainty in ambiguous cases. Drawing on real-world experiences and research, discover practical guidance for balancing clinical responsibility with compassionate patient care. Guest: Michelle M. Mielke, PhD; Allyson Rosen, PhD, ABPP-CN For more information, please visit: https://www.pri-med.com/clinical-resources/podcast/ceoi-alzheimers-diagnostics-pt-3

Overview: In this episode, join us as we discuss the use of blood eosinophils as a biomarker in severe asthma and whether there is prognostic value in measuring eosinophil levels.

Episode key references and resource links:

• Bruselle GG, and Koppelman GH. N Engl J Med. 2022;386(2):157–171.
• Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention 2023. Available from: https://ginasthma.org/2023-gina-main-report/. Access date [June 2023].
• de Groot JC, et al. ERJ Open Research. 2015;1(1):00024–2015.
• Bousquet J, et al. N Engl J Med. 1990;323(15):1033–1039.
• Yancey SW, et al. J. Allergy Clin Immunol. 2017;140(6):1509–1518.

Guest: Dareen Siri, MD, FAAAAI, FACAAI and Matthew Mintz, MD, FACP

Overview: In this episode, join us as we discuss the risks of elevated eosinophil levels and exacerbations, and the role a specialist can play in the management of severe asthma.

Episode references and resource links:

• Price DB, et al. Lancet Respir Med. 2015;3(11):849–858.
• Dougherty RH and Fahy JV. Clin Exp Allergy. 2008;39(2):193–202.
• Chung LP, et al. Respirology. 2020;25(2):161–172.
• Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention 2023. Available from: https://ginasthma.org/2023-gina-main-report/. Access date [June 2023].
• Agusti A, et al. Respir Med. 2021;187:106572.

Guest: Dareen Siri, MD, FAAAAI, FACAAI and Matthew Mintz, MD, FACP

Overview: In this episode, join us as we discuss the importance of blood eosinophil testing for improving diagnosis and phenotyping in severe asthma.

Episode key references and resource links:

• Bruselle GG, and Koppelman GH. N Engl J Med. 2022;386(2):157–171.
• Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention 2023. Available from: https://ginasthma.org/2023-gina-main-report/. Access date [June 2023].
• Heaney LG, et al. Chest. 2021;160(3):814–830.
• de Groot JC, et al. ERJ Open Research. 2015;1(1):00024–2015.
• Fitzpatrick AM, et al. J Allergy Clin Immunol Pract. 2020;8(2):452–463

Guest: Dareen Siri, MD, FAAAAI, FACAAI and Matthew Mintz, MD, FACP

This podcast will review the unique pathophysiology in older adults with long-term Type 2 diabetes that underlie requirements for combination insulin therapy.

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This podcast reviews the specific considerations in appropriately individualizing care for older adults with T2D by reviewing health status, cognition, frailty and their living situation

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