In this episode, we sit down with Alexander Hardy, President and CEO of BioMarin, to talk about his path to leading one of the world's premier rare disease companies. Alexander reflects on his experience across small molecules, biologics, oncology, and rare diseases, and how his work in access and patient services has shaped his thinking about leadership. We discuss the policy environment coming out of Washington — including the IRA and other pricing reforms — and how those factors influence long-term innovation and investment decisions. We also explore the real-world challenges facing rare disease patients, employer concerns about high-cost therapies, and what needs to change over the next five years to improve access and affordability.

• Alexander Hardy
• PathoGenesis
• Eli Lilly | GSK | Novartis
• Genentech — Access Solutions
• BioMarin — Rare Connections
• AUTHrd Act of 2026 (part of the EPIC Act, HR 1492/S832) — pending before Congress
• Health Technology Assessments in Rare Diseases

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In this episode of Prescription for Better Access, we’re joined by William (Bill) Sarraille, a legal expert on drug access and reimbursement. He discusses two developments shaping the pharmacy benefit landscape: the FTC’s enforcement action involving Express Scripts and PBM reforms in the Consolidated Appropriations Act of 2026. Bill explains what these policy changes could mean for benefit design, drug coverage, employer-sponsored plans, and transparency in the PBM market. We also explore potential impacts on formularies, utilization management, contracting practices, and patient out-of-pocket costs, along with possible unintended consequences for employers, manufacturers, and patients seeking timely and affordable access to medicines.

• William (Bill) Sarraille, University of Maryland School of Law
• LinkedIn
• Pharmacy Benefit Managers (PBMs)
• FTC Settlement
• 2024 Administrative Complaint
• Cigna Healthcare
• Fair Market Value in Healthcare
• Consolidated Appropriations Act of 2026
• Part D Plan
• PBMs No Longer Profit From Rebates But Plans Benefit – Pink Sheet
• TPA (Third Party Administrators)
• DOL Proposal
• Copay Accumulators and Maximizers
• Amicus Brief, HIV and Hepatitis Institute

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Employers sit at the center of the U.S. health system as the primary funders of coverage for more than 150 million Americans, yet they struggle with rising costs, fragmented vendors, and uneven outcomes. In this episode, we talk with Dan Mendelson, MPP, CEO of Morgan Health at JPMorgan Chase & Co. and Founder and former CEO of Avalere Health. We explore his journey from health policy to now leading Morgan Health’s efforts to improve the quality, affordability and equity of employer-sponsored healthcare. We’ll learn how Morgan Health evaluates the employer market, where they’re placing investment bets, and how they are testing new care models inside JPMorgan’s own benefit. We then turn to Washington: Dan shares his take on the policy currents that matter most for employers and innovators over the next few years.

• Dan Mendelson, CEO, Morgan Health
• LinkedIn
• Forbes Contributions
• Avalere Health
• Balanced Budget Act of 1997
• Jamie Dimon, Chairman and CEO of JPMorgan Chase & Co.
• Continuation of Health Coverage (COBRA)
• Vera Whole Health, Central Ohio Primary Care
• Centivo
• Embold Health
• Cigna Healthcare
• Quantum Health
• Thyme Care
• 60 Minutes, “$2 million gene therapy could save her baby’s life. But insurance wouldn’t pay”
• PBM Alternatives
• Pharmacy Benefit Managers (PBMs)
• Individual Coverage Healthcare Reimbursement Accounts (ICHRA)

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Email us at comments@prescriptionforbetteraccess.com.
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