Pitstop: APOL1 and Kidney Disease: From Theory to Practice

Advances in genetics have transformed how we understand kidney disease, and the discovery of APOL1 has been a major milestone. In this episode of Kidney Commute: Pitstop, host Dr. Osama El Shamy is joined by Meyeon Park, MD, MAS and Denay Richards, PhD to explore the role of APOL1 genetic variants in kidney disease development and progression.

The discussion covers the epidemiology of APOL1, the interplay between genetic risk and environmental factors, and scenarios in which APOL1 genetic testing may be considered. Speakers also address how test results are communicated to patients and families, implications for disease management, emerging research into APOL1 targeted therapies, and the significance of newly introduced ICD 10 codes for APOL1 mediated kidney disease.

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This educational episode is supported by Vertex Pharmaceuticals.