Episodios

  • Possible: Lisa Su on semiconductors, compute, and big bets
    Nov 15 2025

    What’s the role of semiconductors—and the companies that make them—in powering human progress? What does it look like to innovate thoughtfully in a landscape where the demand for power may be higher than the supply? With AI evolving faster and faster, how can we keep up?

    Advanced Micro Devices (AMD) CEO Lisa Su joins the show to talk about hardware, global manufacturing, and risk-taking. She shares what she has learned leading AMD from near-bankruptcy a decade ago to its current standing as one of the world’s leading chipmakers. Lisa also weighs in on geopolitics, the AI arms race, startups, what makes her want to hire someone, and AI’s enormous potential to advance healthcare for humankind.

    For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    43 m
  • How AI can unlock life-saving cures, with Siddhartha Mukherjee
    Nov 12 2025

    Discovering new medicines has long been a slow, inefficient, and expensive process. Siddhartha Mukherjee, esteemed cancer biologist and author of the Pulitzer Prize-winning book The Emperor of All Maladies, is looking to change that. That’s why he partnered with Reid Hoffman to found Manas AI, a company that uses AI to accelerate drug discovery and develop life-saving cures faster and cheaper. He joins Pioneers of AI to discuss which parts of the drug development process are transformed by AI, how generative AI tools based on physics and chemistry differ from other LLMs, and why creating Manas AI was a leap of faith.

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    29 m
  • Designing AI for people and the planet, with Aza Raskin
    Nov 5 2025

    AI is rapidly changing what it means to be human, but is AI development truly human-centered? According to Aza Raskin, co-founder of the Center for Humane Technology, the answer is largely “no.” The man who invented the “infinite scroll” is now working to understand why the most powerful technology so often fails to prioritize the human experience and our collective well-being. Raskin is also leading the Earth Species Project — using AI to better understand the animals that live alongside us, by unlocking patterns in vast amounts of data on animal communication. He joins Pioneers of AI to talk about both of these dynamic endeavors, with the flourishing of humans and Earth at the core.

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    45 m
  • Baratunde Thurston wants us to reimagine our relationship with AI
    Oct 29 2025

    How we decide to live with AI, at home or at work, will greatly impact our personal and professional futures. Baratunde Thurston, a comedian, writer, and commentator, has had a long career exploring what a harmonious relationship between human beings and our machines could look like. Now, as host and co-creator of the podcast Life with Machines, he explores what it means to live and collaborate well with AI, by talking with the people helping to shape our new reality. Thurston joins Pioneers of AI for a dynamic conversation about Life with Machines’ first year, building and working with the show’s AI-producer named Blair, and how AI should help us reconnect with our own humanity.

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    37 m
  • Could this be the future of K-12 education?, with Alpha School’s Joe Liemandt
    Oct 22 2025

    Educators around the world are wrangling with AI in learning. At Alpha School, a private K-12 school based in Texas, students use AI-driven software to complete core subjects in about two hours’ time. They spend the rest of the school day with guides for social-emotional learning, project-based work, and life skills. Joe Liemandt, longtime software developer and investor, serves as the principal of Alpha School. Dr. Rana el Kaliouby joined him on stage at this year’s Masters of Scale Summit, along with Alex Matthew, an Alpha School high schooler. They discuss what students need to be prepared for the future, and the challenges in scaling Alpha School’s model.

    You can find all the Masters of Scale Summit stage sessions on our YouTube channel: https://www.youtube.com/playlist?list=PL4Tp7I0LquJtwF7CEU-B5sm7Eyuk3Aqma

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    25 m
  • Vibe coding and the one-person startup, with Lovable's Anton Osika
    Oct 15 2025

    “Vibe coding” is taking software development by storm, allowing users to build apps by simply chatting with AI. These tools will transform how digital products and companies are created – and who gets to create them. Anton Osika is the co-founder and CEO of Lovable, a vibe coding platform that’s garnered a reported $4 billion valuation since its founding in 2023. Host Dr. Rana el Kaliouby sat down with Osika live on stage at this year’s Masters of Scale Summit to discuss how vibe coding is rewriting the rules of creation and democratizing access to entrepreneurship, and how it will impact software engineering and computer science in the future.

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    21 m
  • Rapid Response: Hollywood’s hottest AI partner, with Runway’s Cristóbal Valenzuela
    Oct 8 2025

    AI tools are disrupting all types of creative content, and Runway AI is a pioneer making major waves in Hollywood. In this episode of Rapid Response, Runway’s co-founder & CEO Cristóbal Valenzuela dissects the company’s breakneck growth, the risks and responsibilities of AI tool makers, and how AI is redefining both business expectations and our notion of creativity.

    Visit the Rapid Response website here: https://www.rapidresponseshow.com/

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    33 m
  • How Harvey is reinventing legal work with AI
    Oct 1 2025

    Law is one of the oldest professions in the world, a storied occupation steeped in traditions, where innovation can be challenging. Gabe Pereyra wants to change that with the power of AI. As Co-founder and President of Harvey, he’s creating legal AI tools that augment lawyers in their daily work, from drafting proposals to conducting research. Pereyra joins Pioneers of AI to discuss how Harvey supports lawyers, what it takes to build a growing AI company, and how the legal playbook is shifting.

    Learn more about Pioneers of AI: http://pioneersof.ai/

    Follow Pioneers of AI on all channels: https://linktr.ee/pioneersofai

    At the center of AI is people, so we want to hear from you! Share your experiences with AI — or ask us a burning question — by leaving a voicemail at 601-633-2424. Your voice could be featured in a future episode!

    See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

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    34 m