Ozempic and Wegovy Weight Loss: Benefits, Risks, and Expert Nutrition Guidance

Recent research from the University of Cambridge highlights a key concern with popular weight-loss drugs like Ozempic and Wegovy. These medications sharply reduce appetite, leading to calorie intake dropping by sixteen to thirty-nine percent, which drives effective weight loss for people with obesity. However, experts from University College London and the University of Cambridge warn that many users lack proper nutrition guidance, risking muscle loss of up to forty percent of total weight shed and deficiencies in protein, vitamins, and minerals that could cause fatigue, weakened immunity, hair loss, or osteoporosis. Dr. Adrian Brown from UCL stresses integrating nutritional care, such as prioritizing nutrient-dense foods and even protein distribution across meals, drawing from post-bariatric surgery practices to preserve lean mass and support long-term health.

Oprah Winfrey has been candid this week about her experience with these GLP-1 drugs, including Ozempic, sharing how they silenced the constant food noise in her brain and helped her lose over fifty pounds since starting in twenty twenty-three, combined with hiking and resistance training. In interviews on The Oprah Podcast and CBS Sunday Morning, the seventy-one-year-old media icon revealed she quit the drug after six months, only to regain twenty pounds despite strict diet and exercise, proving to her it is a lifetime tool, much like blood pressure medication. Oprah described overcoming deep shame from decades of self-blame and public ridicule, now viewing obesity as a clinical disease beyond personal willpower, not a moral failing. She emphasized to People Magazine and on The View that the medications feel like relief and redemption, enabling her to reach one hundred fifty-five pounds and feel in the best shape of her life, while rejecting stigma around using them responsibly alongside lifestyle changes.

These insights underscore the drugs transformative impact, though experts urge balanced approaches to avoid pitfalls.

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